HCoV-229E is one of the seven human coronaviruses which include HCoV-NL63, HCoV-OC43, HCoV-HKU1, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 and are globally distributed. (wikipedia.org)
The other six are: Human coronavirus NL63 (HCoV-NL63) Human coronavirus OC43 (HCoV-OC43) Human coronavirus HKU1 (HCoV-HKU1) Middle East respiratory syndrome-related coronavirus (MERS-CoV) Severe acute respiratory syndrome coronavirus (SARS-CoV-1) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Chloroquine, a zinc ionophore, inhibits the replication of Human coronavirus 229E in cell culture. (wikipedia.org)
Human HCoV-229E, and human HCoV-NL63, likely originated from bats. (wikipedia.org)
These comprise the Beta-coronaviruses OC43 and HKU-1, which have 38% and 35% amino acid homology with SARS-CoV-2, and the more distantly related Alpha-coronaviruses NL63 and 229E, each with around 31% homology 11 . (nature.com)
Four of those, HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU1, are non-zoonotic and cause worldwide outbreaks of upper respiratory tract infections (URTI) predominantly in the winter period [ 2 ]. (biomedcentral.com)
Samples were tested for anti-spike IgG against SARS-CoV-2, HCoV-229E, HCoV-HKU1, HCoV-NL63, and HCoV-OC43 antigens. (frontiersin.org)
however, levels for HCoV-229E and HCoV-NL63 were similar (suggesting that vaccination did not affect these baseline values). (frontiersin.org)
Among vaccinated individuals without prior COVID-19 infection, SARS-COV-2 anti-spike IgG demonstrated a weak positive relationship between both HCoV-229E (r = 0.11) and HCoV-NL63 (r = 0.12). (frontiersin.org)
From the adjusted log-log multiple regression model, higher HCoV-229E and HCoV-NL63 anti-spike IgG antibodies were associated with increased SARS-COV-2 anti-spike IgG antibodies. (frontiersin.org)
Anti-HCoV-229E and HCoV-NL63 antibodies were unaffected by vaccination, and higher levels were associated with significantly higher COVID-19 vaccine-induced SARS-COV-2 antibodies. (frontiersin.org)
They were caused by coronaviruses 229E, NL63 and OC43, influenza B virus, respiratory syncytial virus A, rhinovirus and human metapneumovirus. (bmj.com)
Coronaviruses 229E, OC43, NL63, and HKU1 cause about 15 to 30% of cases of the common cold. (msdmanuals.com)
Most people are infected with common coronaviruses throughout their lives, but only four of them cause common cold symptoms: alpha coronavirus 229E and NL63 and beta coronavirus OC43, HKU1 (V) 1 . (bvsalud.org)
Coronavirus 229E3
Human coronavirus 229E (HCoV-229E) is a species of coronavirus which infects humans and bats. (wikipedia.org)
Coronavirus 229E, a Group 1 CoV, is propagated in the HeLa or MRC-5 cell line. (h-h-c.com)
NS oil was tested as an antivirus against low pathogenic coronavirus (229E). (bvsalud.org)
OC432
In addition to SARS-CoV, there are two pathogenic human coronaviruses that are adapted to propagation and assay in cell culture, 229E and OC43, which could serve as surrogates for SARS-CoV in survival studies. (asm.org)
However, previous studies suggested that the survival of 229E and OC43 on surfaces may be shorter than that of SARS-CoV ( 10 , 35 ). (asm.org)
Pathogenic1
Therefore we investigated the virucidal and antiviral potential of Echinacea purpurea (Echinaforce®) against human coronavirus (HCoV) 229E, highly pathogenic MERS- and SARS-CoVs, as well as the newly identified SARS-CoV-2, in vitro. (biomedcentral.com)
Human3
HCoV-229E is also among the coronaviruses most frequently codetected with other respiratory viruses, particularly with human respiratory syncytial virus (HRSV). (wikipedia.org)
The investigators used the human coronavirus HCoV‐229e as a surrogate for SARS-CoV-2. (medscape.com)
the new paradigm for the global havoc that can be pro- coronavirus (CoV) 229E reverse primer (7), and human duced by an emerging infectious disease (1). (cdc.gov)
Alphacoronavirus1
HCoV-229E is a member of the genus Alphacoronavirus and subgenus Duvinacovirus. (wikipedia.org)
Respiratory3
HCoV-229E is associated with a range of respiratory symptoms, ranging from the common cold to high-morbidity outcomes such as pneumonia and bronchiolitis. (wikipedia.org)
there is a single published case report to date of a 229E infection that caused acute respiratory distress syndrome (ARDS) in an otherwise healthy patient having no detectable co-infection with another pathogen. (wikipedia.org)
However, we did observe a protective effect in an organotypic respiratory cell culture system by exposing pre-treated respiratory epithelium to droplets of HCoV-229E, imitating a natural infection. (biomedcentral.com)
Infection3
A NCBI-study found a previous HCoV-229E infection in 42.9% - 50.0% of children of 6-12 months of age and in 65% of those 2.5-3.5 years of age. (wikipedia.org)
Antibacterial and anti-corona virus (229E) activity of Nigella sativa oil combined with photodynamic therapy based on methylene blue in wound infection: in vitro and in vivo study. (bvsalud.org)
Pre-treatment of cell lines, however, did not inhibit infection with HCoV-229E and post-infection treatment had only a marginal effect on virus propagation at 50 μg/ml. (biomedcentral.com)
Symptoms1
229E, for example, causes symptoms like those present in the common cold according to one paper . (as.com)
Cell culture1
These results show that Echinaforce® is virucidal against HCoV-229E, upon direct contact and in an organotypic cell culture model. (biomedcentral.com)
Found1
In the current study, we found that HCoV-229E was irreversibly inactivated when exposed to Echinaforce® at 3.2 μg/ml IC 50 . (biomedcentral.com)
Coronaviruses2
HCoV-229E is also among the coronaviruses most frequently codetected with other respiratory viruses, particularly with human respiratory syncytial virus (HRSV). (wikipedia.org)
HCoV-229E is one of seven known coronaviruses to infect humans. (wikipedia.org)
Coronavirus HCoV-229E2
1. Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells. (nih.gov)
Dr. Gerba found in his studies that these coated surfaces were effective against human coronavirus (HCoV) 229E, 'reducing the concentration of these viruses by greater than 90% in 10 minutes and by greater than 99.9% after two hours of contact. (go.com)
Spike1
Gentaur Protein Type: Human coronavirus 229E (HCoV-229E) Spike glycoprotein Design Principles: 291 polypeptides, each peptide contains 15aa, 11aa. (proteomecommons.org)
Humans1
The researchers were studying another coronavirus, called 229E, that causes only a mild cold in humans. (keranews.org)
Strains1
People imprinted with first CoV-229E they are infected by, but still generally neutralize later strains to which they are exposed. (slides.com)