• Preliminary study on the association of AQP4 promoter polymorphism with anti-aquaporin-4 antibody positivity in southern Han Chinese patients with idiopathic demyelinating disorders of central nervous system. (cdc.gov)
  • In most cases, NMO is caused by antibodies that the body develops to a protein called aquaporin-4 (AQP4). (medicalxpress.com)
  • Association Between the Single Nucleotide Polymorphism and the Level of Aquaporin-4 Protein Expression in Han and Minority Chinese with Inflammatory Demyelinating Diseases of the Central Nervous System. (cdc.gov)
  • To address this, the researchers used a clinically relevant rat model of NMO to test the effects of the anti-RGMa antibody on disease symptoms, as well as gene and protein expression. (medicalxpress.com)
  • Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hypertensive disorders in women. (ircabral.com)
  • Some of the single-nucleotide polymorphisms (SNPs) in TONEBP introns are cis -expression quantitative trait loci that affect TONEBP transcription. (nature.com)
  • Interstitial tonicity controls TonEBP expression in the renal medulla. (nature.com)
  • Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression. (nature.com)
  • Association of the HLA-DPB1*0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders. (cdc.gov)
  • This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology. (hindawi.com)
  • This notion has been challenged by the discovery of new membrane transport functions, especially those exerted by aquaporins (AQPs), a family of membrane channel proteins widespread in nature [ 10 , 11 ]. (hindawi.com)
  • The incubation and fledging durations 23±3 days 43±6 days (Medway 1957;Langham 1980;Lim 2002) Swiftlets engage in yearround breeding activities between the months of October and February (Langham 1980) Construction of a single nest by swiftlets typically requires around 30-45 days during the breeding season, but in the nonbreeding season, this process takes approximately 60-80 days (Aowphol et al. (researchgate.net)
  • Aquaporin-4-autoimmunity in patients with systemic lupus erythematosus: A predominantly population-based study. (cdc.gov)
  • Systemic sublethal administration of Shiga toxin 2 increased the expressions of astrocytic GFAP and microglial Iba1, and decreased the expressions of endothelial glycocalyx, NeuN neurons from CA1 pyramidal layer and oligodendrocytic MBP myelin sheath from the fimbria of the hippocampus. (biomedcentral.com)
  • Acutely and chronically, lithium salts produce a natriuresis that is associated with an impaired regulation of the expression of the epithelial sodium channel in the cortical collecting tubule. (medscape.com)
  • ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. (thermofisher.com)
  • 2018 . Visceral leishmaniasis-associated nephropathy in hospitalised Brazilian patients: new insights based on kidney injury biomarkers . (ajtmh.org)
  • Red cell membranes isolated from individuals with autosomal recessive HS have only 40-50% of the normal amount of spectrin (relative to band protein 3). (medscape.com)
  • Characterization of RAGE and CK2 Expressions in Human Fetal Membranes. (igred.fr)
  • Aquaporins and Fetal Membranes From Diabetic Parturient Women: Expression Abnormalities and Regulation by Insulin. (igred.fr)
  • Gene expression profiling is increasingly used in the field of infectious diseases for characterization of host, pathogen and the nature of their interaction. (cambridge.org)
  • The purpose of this study was to develop a robust, standardized method for comparative expression profiling and molecular characterization of Leishmania donovani clinical isolates. (cambridge.org)
  • Intracellular amastigote protocols need further refinement, but we describe a first generation tool for high-throughput comparative molecular characterization of patients' isolates, based on the changing expression profiles of promastigotes during in vitro differentiation. (cambridge.org)
  • Fulcrum reports interim data from 29 patients enrolled in the 48-week, 80 patient, Phase IIb ReDUX4 trial, where treatment with losmapimod did not reduce DUX4-driven gene expression in affected skeletal muscle biopsies at 16-weeks, compared to placebo in patients with facioscapulohumeral muscular dystrophy. (prescriberight.com)
  • Despite the lack of effect in an interim analysis, Fulcrum plans to continue the ReDUX4 trial, because in patients with the highest pre-treatment DUX4-driven gene expression, losmapimod reduced DUX4-driven gene expression more than placebo. (prescriberight.com)
  • The anti-mog spectrum in children is equally variated: Out of a sample of 41 children with MOG-antibodies 29 had clinical NMOSD (17 relapsing), 8 had ADEM (4 relapsing with ADEM-ON), 3 had a single clinical event CIS, and 1 had a relapsing tumefactive disorder. (mdwiki.org)
  • Journal of neuroimmunology 2012 Oct 251 (1-2): 110-3. (cdc.gov)
  • Journal of neuroimmunology 2013 Feb 255 (1-2): 75-80. (cdc.gov)
  • We identified 98 candidate genes containing rare variation that in aggregate show association with SLE many of which have recognized immunological function, but also function and expression related to relevant tissues such as the joints, skin, blood or central nervous system. (frontiersin.org)
  • Expression is regulated in some tissues by VITAMIN D. (lookformedical.com)
  • O echipă medicală din Turcia a raportat un caz de endometrioză la un bărbat de 49 de ani care suferea de hernie inghinală, având 3 intervenții chirurgicale în zona respectivă. (endoro-online.org)
  • ZO-1 expression is significantly reduced in many breast cancer lines. (thermofisher.com)
  • As the grade of severity in HUS cases is usually associated with neurological dysfunctions, the mortality rate rises significantly between 2 to 3-folds when the CNS is involved [ 7 ]. (biomedcentral.com)
  • Structure and function of aquaporin water channels. (nih.gov)
  • Both groups will be treated with standard therapy of ST-segment elevation myocardial infarction (STEMI), with the CDDP group administrating 20 tablets of CDDP before pPCI and 10 tablets 3 times daily after pPCI, and the control group treated with a placebo simultaneously. (bvsalud.org)
  • Mice were intraperitoneally injected with 25 mg/kg CHK1 inhibitor AZD7762 and 20 mg/kg gemcitabine for 3 weeks. (bvsalud.org)
  • We chose to use expression-curves rather than single, specific, time-point measurements to capture this biological variation. (cambridge.org)
  • These SNPs are associated with increased risk of type 2 diabetes mellitus, diabetic nephropathy, inflammation, high blood pressure and abnormal plasma osmolality, indicating that variation in TONEBP expression might contribute to these phenotypes. (nature.com)
  • All-trans-retinoic acid regulates aquaporin-3 expression and related cellular membrane permeability in the human amniotic environment. (igred.fr)
  • Tissue extracts of Mouse Testis (Lane 6) and Mouse Kidney (Lane 7) were electrophoresed using NuPAGE™ 3-8% Tris-Acetate Protein Gel (Product # EA0378BOX). (thermofisher.com)
  • I have become particularly interested in variations of creatinine and glomerular filtration rate and declining levels of function at the stage 2 and stage 3 kidney disease. (drprincetta.com)
  • However, I am interested in how to improve kidney function in early kidney decline such as with stage 2 and 3 kidney disease on an outpatient basis. (drprincetta.com)
  • Stage 2 kidney disease is defined as an eGFR between 60 to 89 milliliters per minute, and stage 3 kidney disease is defined as an eGFR between 30 and 59 milliliters per minute. (drprincetta.com)
  • After signaling the research treatment, you include three systems:( 1) IBIDS Consumer Database,( 2) Full IBIDS Database, or( 3) Peer Reviewed interventions So. (seabaygame.com)
  • The Molecular Chaperone CCT Sequesters Gelsolin and Protects it from Cleavage by Caspase-3. (gu.se)
  • Besides Stx2 pathogenicity, lipopolysaccharide (LPS) is another virulence factor that is also released form EHEC [ 3 ], for being a Gram negative bacteria. (biomedcentral.com)
  • Neurobiology of disease 2010 Feb 37 (2): 349-55. (cdc.gov)