LigandsDetergents20212018BifunctionalEDTADesferalGadoliniumAbstractDerivatives2017BoundAdditivesSolventForecast PeriodTherapeuticMetalsProceedingsToxicWater-solubleIronSubstancesSynthesisIonsSodiumNitrogenLikelihoodMetalAssessmentCancerContrast agentsGOODAcidLiverSurvivalProductsReviewGroupGrowthIncreaseTreatmentProvideShare

Ligands5

• In theory, once the chelating ligands have bound to the actinides, the heavy metal complexes can exit the body naturally by urination. (wikipedia.org)
• The chelating ligands act as more active agents than non-chelating ligands. (ijsr.net)
• Benzaldehyde and substituted benzaldehydes react with hydroxyl amine, semicarbazide, hydrazine etc. to give derivatives like oximes, semicarbazones, and hydrazones which act as good chelating ligands. (ijsr.net)
• When the chelating ligands are complexed with the metal ions their activities may alter. (ijsr.net)
• In chemistry , a coordination complex or metal complex consists of a central atom or ion , which is usually metallic and is called the coordination centre , and a surrounding array of bound molecules or ions, that are in turn known as ligands or complexing agents. (naturehacker.org)

Detergents2

• The scope of clean alternatives in multiple industries such as the oil processing market, detergents, and garment market combined with the augmented expansion of eCommerce sectors in developing countries like India, Brazil, and Mexico owing to the large scale supply of the products is expected to create lucrative opportunities for the natural chelating agents market. (marketresearchcommunity.com)
• Ethylenediamine (EDA) is a bifunctional amine used for several different purposes such as for production of the Ethylenediaminetetracetric acid (EDTA) that is used as a chelating agent in detergents but also for fungicides, bleaching activators etc. (chalmers.se)

20211

• Natural Chelating Agents Market was valued at USD 4.5 Billion in 2021, registering a CAGR of 4.5% during the forecast period (2022-2030), and the market is projected to be worth USD 6.8 Billion by 2030. (marketresearchcommunity.com)

20183

• 2018. Prevention of Metal Exposure: Chelating Agents and Barrier Creams . (instem.res.in)
• This reduction was based on the 97.5% percentile level in the general population measured in the 2015-2016 and 2017-2018 National Health and Nutrition Examination Survey cycles (NHANES) (Ruckart PZ, Jones RL, Courtney JG et al. (cdc.gov)
• To reinforce the antimicrobial drug pipeline, the European Union's European Medicines Agency authorized the clinical use of ceftazidime/avibactam (CZA) in 2016, meropenem/vaborbactam (MVB) in 2018, and cefiderocol (FDC) in 2020. (cdc.gov)

Bifunctional1

• Bifunctional chelating agent with a free primary amine. (chematech-mdt.com)

EDTA3

• Additionally, the harmful impacts of toxic synthetic chelating agents such as nitrilotriacetic acid and ethylenediaminetetraacetic acid (EDTA) owing to the non-biodegradability and high water insolubility also restrict the growth of natural chelating agents market during the forecast period. (marketresearchcommunity.com)
• Chelation therapists around the world incorporate EDTA treatments in their daily practice, often unaware of the chemical differences of the various chelating agents. (microtrace.eu)
• The chelating agents most commonly used to treat chronic metal overexposures are DMSA, DMPS and EDTA. (microtrace.eu)

Desferal1

• Desferal belongs to a group of drugs called chelating agents. (rxwiki.com)

Gadolinium5

• An article published today (6 April) in the Springer journal BioMetals raises serious questions about the safety of the gadolinium-based contrast agents that are used in about 30 percent of magnetic resonance imaging (MRI) scans. (medicaldesignandoutsourcing.com)
• According to lead author Moshe Rogosnitzky, "Although gadolinium is bound to chelating agents designed to flush out the rare metal following an MRI, it has been found to deposit in the brain, bone, and other organs. (medicaldesignandoutsourcing.com)
• In 2007, the U.S. Food and Drug Administration (FDA) ordered a black box warning for gadolinium-based contrast agents following the discovery that patients with kidney disease were developing nephrogenic systemic fibrosis (NSF) due to the inability to clear gadolinium from their bodies. (medicaldesignandoutsourcing.com)
• In July 2015, the FDA announced it was evaluating the risk of brain-deposits in patients who undergo repeated exposure to gadolinium-based contrast agents. (medicaldesignandoutsourcing.com)
• Used in LGE assessment, gadolinium is an extracellular chelating agent that permeates the interstitial space of both normal and abnormal myocardium . (medscape.com)

Abstract1

• Abstract: Today's printing inks are composed of a pigment a binder (an oil, resin or varnish of some kind), a solvent and various additives such as drying and chelating agents. (ijirg.com)

Derivatives1

• Haddad, H. (2016) A New Schiff Base Derivatives Designed to Bind Metal Ion (Cu, Co): Thermodynamics and Biological Activity Studies. (scirp.org)

20173

• According to the latest report published by Credence Research, Inc. Phosphorous Trichloride Market - Growth, Future Prospects and Competitive Analysis, 2017-2025, the global phosphorous trichloride market was valued at US$ 1.37 Bn in 2016, and is expected to reach US$ 2.27 Bn by 2025, expanding at a CAGR of 5.0% from 2017 to 2025. (activeboard.com)
• 2017. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition . (lsrnw.ac.uk)
• 2017. Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents . (lsrnw.ac.uk)

Bound1

• We evaluated and compared the effectiveness of each of those chelating agents and statistically determined what metals are best bound. (microtrace.eu)

Additives1

• Based on application areas, this report studies the global phosphorous trichloride market for organophosphorus pesticides, flame retardants, organophosphorus chelating agents, Plastic additives and other applications. (activeboard.com)

Solvent1

• 1 wt% chelating compound in the solvent. (aiche.org)

Forecast Period2

• Thus, favorable regulations for increased demand for vegan cosmetic products are expected to boost the natural chelating agents market during the forecast period due to the large usage of natural chelating agents. (marketresearchcommunity.com)
• The market for organophosphorous chelating agents is anticipated to witness the fastest growth rate during the forecast period due to growing research and commercialization initiatives taken in biotechnology, life sciences and pharmaceutical space. (activeboard.com)

Therapeutic3

• Therapeutic potential of silymarin as a natural iron-chelating agent in β-thalassemia intermedia. (greenmedinfo.com)
• This study reports conversion of a previously reported 68Ga-imaging agent, [68Ga]Ga-P16-093, to a Lu-177 radionuclide therapeutic agent. (bvsalud.org)
• The switch from chelator HBED-CC to DOTA(GA)2 and the switch from the imaging isotope gallium-68 to the therapeutic isotope lutetium-177 have successfully transformed a PSMA-targeting agent from diagnosis to promising radionuclide therapeutic agents. (bvsalud.org)

Metals1

• We propose herein a novel combination therapy consisting of an agent for chelating redox-active metals (Fe2+) and/or an antioxidant to reduce damage caused by residual oxygen free radicals, in addition to resveratrol, a modulator of AMPK and sirtuin pathways (nuclear transcription). (mundoseculoxxi.com.br)

Proceedings1

• The proceedings were held on March 21, 2016 beginning at 3:00 p.m. (cdc.gov)

Toxic2

• It would function by coordinating as a chelating ligand with toxic actinides in the body before they can cause significant damage. (wikipedia.org)
• The surging use of natural chelating agents especially in the manufacturing of cosmetic products is expected to contribute to the growth of the natural chelating agents market due to non-toxic and environment-friendly applications. (marketresearchcommunity.com)

Water-soluble2

• The chelating agent is known as a chemical compound that reacts with the metal ions for the formation of water-soluble and stable metal complexes. (marketresearchcommunity.com)
• It is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry. (mohebtc.com)

Iron3

• Alpha-lipoic acid possesses excellent iron chelating properties. (greenmedinfo.com)
• For her doctoral work, she synthesised and characterised siderophore analogs to investigate how bacteria transport iron and to develop new iron chelating agents. (wikipedia.org)
• Among them, Deferasirox, 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid, is an iron chelating agent and it is indicated for the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis). (google.com)

Substances1

• A synergistic combination of a selected antioxidant substances, Fe2+ chelating agents and resveratrol may be expected to provide a more clinically successful treatment. (mundoseculoxxi.com.br)

Synthesis1

• 2016. Design and synthesis of potent in vitro and in vivo anticancer agents based on 1-(3′,4′,5′-Trimethoxyphenyl)- 2-Aryl-1H-Imidazole . (lsrnw.ac.uk)

Ions1

• Natural chelating agents are biodegradable chemical compositions that bind with the metal ions and play a vital role in the efficacy and stability of multiple products such as agrichemicals, cosmetics, and food & beverage. (marketresearchcommunity.com)

Sodium2

• For instance, natural chelating agents received acceptance from regulatory authorities like the National Institute of Health and Food and Drugs Administration in terms of safe for use on the skin and eyes, which resulted in the large usage of natural chelating agents such as sodium gluconate and glutamic acid diacetate (GLDA) in cosmetic products. (marketresearchcommunity.com)
• The factors such as rising inclination towards natural substitutes like sodium gluconate to conventional sequesters especially in cosmetic, detergent, and cleaning products, rising cleaning applications due to increased hygiene awareness among the population, and growing expenditure from major industry players for facilitation of innovative, clean products are projected to accelerate the natural chelating agents market in the Asia Pacific region. (marketresearchcommunity.com)

Nitrogen1

• Furthermore, the rising demand for natural chelating products due to low nitrogen toxicity and biodegradability are the major factors that fuel the growth of the natural chelating agents market. (marketresearchcommunity.com)

Likelihood1

• The agent rearranges the chemical composition of metal to improve the general bonding likelihood and stability. (marketresearchcommunity.com)

Metal3

• At present, it is assumed that the application of higher amounts of a chelating agent increases metal binding and thus the detoxification process. (microtrace.eu)
• As it is a good chelating agent, many metal II complexes have been synthesized with anti-tubercular activity. (jatstech.org)
• Substitution of the HBED-CC metal chelating group with DOTA(GA)2 led to P17-087 (4) and P17-088 (7). (bvsalud.org)

Assessment1

• They are working to assess the long-term risk in a full environmental public health assessment expected by fall 2016. (multco.us)

Cancer1

• Results suggest that [177Lu]Lu-P17-079 ([177Lu]Lu-1) is a promising candidate for further development as a hetero-bivalent radionuclide therapy agent targeting both PSMA expression and bone metastases for the treatment of prostate cancer. (bvsalud.org)

Contrast agents3

• The introduction of hepatobiliary contrast agents that are actively taken up by hepatocytes gives an opportunity to assess liver function. (docksci.com)
• This is needed to guide the choice of preventive methods, achieve accurate diagnoses, implement effective treatment approaches, and spark research for the design of safer contrast agents and imaging protocols. (medicaldesignandoutsourcing.com)
• Taking alpha-lipoic acid by mouth with or without standard hydration therapy during a coronary angiography doesn't seem to prevent kidney damage caused by contrast agents. (medlineplus.gov)

GOOD1

• Schiff bases are known to be good chelating agents and easily prepared and characterized. (scirp.org)

Acid4

• The agent under investigation is an octadentate ligand consisting of four cross-linked dipicolinic acid components (Figure 2). (wikipedia.org)
• The increased rising demand from the cosmetic industry for reduced risks of oxidation and rancidity and increased awareness of biodegradable sequestering agents such as ethylene diamine disuccinate (EDDS) and glutamic acid diacetate (GLDA) are the major factors that boost the growth of natural chelating agents market. (marketresearchcommunity.com)
• As an alkylating agent, the mechanism of action of the active metabolites may involve cross-linking of deoxyribonucleic acid (DNA), which may interfere with the growth of normal and neoplastic cells. (medscape.com)
• Some physicochemical characteristics influence the erosivity of food like the type of acid, pH, titratable acidity, chelating potential, calcium and phosphate concentration, temperature and adhesion 4 . (bvsalud.org)

Liver1

• These agents are proving to be valuable in the evaluation of functional reserve in patients undergoing major liver resections and for liver donors. (docksci.com)

Survival1

• Several preliminary studies have demonstrated that the addition of cytokines (eg, granulocyte colony-stimulating factor [G-CSF], granulocyte-macrophage colony-stimulating factor [GM-CSF]) may hasten the neutrophil recovery and that these agents may improve response rate and survival, although long-term use may increase the risk of clonal evolution. (medscape.com)

Products1

• Thus, rising demand for clean, animal cruelty products among the population is estimated to contribute to the growth of the natural chelating agents market. (marketresearchcommunity.com)

Review1

• Resources Third Quarter Review 2016 Hexion Inc. (azurewebsites.net)

Group2

• In recent work by the BioActinide Research group, different actinide chelating agents have been synthesised which could be used to selectively bind radionuclides in the human body in order to safely remove them. (wikipedia.org)
• 2012-03-22 Assigned to DEUTSCHE BANK AG, LONDON BRANCH, AS SECURITY AGENT reassignment DEUTSCHE BANK AG, LONDON BRANCH, AS SECURITY AGENT PATENT SECURITY AGREEMENT SUPPLEMENT Assignors: ACTAVIS GROUP PTC EHF. (google.com)

Growth3

• Additionally, increased demand for vegan cosmetics is also expected to support the growth of natural chelating agents owing to the growing use of natural chelating agents in cosmetic production. (marketresearchcommunity.com)
• In the context of the region, Asia Pacific is anticipated to contribute to the growth of the natural chelating agents market. (marketresearchcommunity.com)
• The lack of awareness of natural chelating agents hampers the growth of the natural chelating agents market due to reduced industry penetration. (marketresearchcommunity.com)

Increase1

• Approximately 6.2 million people in the United States had heart failure (HF) between 2013 and 2016, and prevalence of the condition continues to increase over time as the population ages. (medscape.com)

Treatment2

• The use of diagnostics aids the physician in setting therapy schedules, allows proper selection of the most useful chelating agent for the patient's condition, and monitors treatment success. (microtrace.eu)
• Treatment decisions should not be based on urine leads, particularly those done after administration of a chelating agent. (cdc.gov)

Provide1

• Dr. Knutson reported that NCEH/ATSDR became involved in the Flint response on January 11, 2016 to provide federal leadership of the scientific and communication activities. (cdc.gov)

Share1

• Being the largest downstream consuming area, organophosphorous pesticides capture over 65% of the global market share in 2016. (activeboard.com)