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  • suppressor genes
  • AT/RT has been linked to somatic and germline mutations of SMARCB1 and, less commonly, SMARCA4 , both of which are tumor suppressor genes. (cancer.gov)
  • Here, we present an overview of AN in the SVZ-OB and olfactory epithelium (OE) in mice and humans followed by a comprehensive update of the distinct roles played by cell cycle proteins including major tumors suppressor genes in various steps during neurogenesis. (frontiersin.org)
  • resection
  • Infants with brain tumors may clearly benefit from surgical resection with favorable results even for prolonged periods of time. (springer.com)
  • We retrospectively analyzed a consecutive cohort of 30 patients in their first 6 months of life (aged 183 days or younger) who underwent resection for a brain tumor in the Department of Neurosurgery, The National Hospital, Oslo, Norway, between 1973 and 2012. (springer.com)
  • Resection is not an option and the tumors are resistant to other therapeutic measures. (frontiersin.org)
  • 1999
  • A potential association was found for exposure to ambient air concentrations of suspected neurotoxicant hazardous air pollutants, specifically aromatic solvents, among place of residence in 2002 and 1999 and risk of Amyotrophic Lateral Sclerosis. (mdibl.org)
  • In the adult participants of NHANES from 1999 to 2002, total thyroxine was negatively associated with serum dioxin-like toxic equivalents in a dose-dependent fashion, with stronger associations in women than men. (mdibl.org)
  • Infantile
  • The authors report on their institutional experience with both tumors, focusing on radio-graphic features, especially the diffusion studies, which might be useful in distinguishing between infantile GBM and DIT. (thejns.org)
  • A retrospective review was undertaken of all infantile brain tumors treated at British Columbia's Children's Hospital between 1982 and 2012, and cases of GBM and DIT were recorded. (thejns.org)
  • Magnetic resonance imaging, especially diffusion-weighted imaging, may be a useful aid in distinguishing between infantile GBM and DIT tumors, with infantile GBM demonstrating restricted diffusion. (thejns.org)
  • World Health Organ
  • In a 2002-2003 World Health Organization exposure study, 13 pools of breast milk comprising samples from 316 primiparous women in Hong Kong in 2002 were analyzed by gas chromatography/mass spectrometry for 29 polychlorinated dibenzo-para-dioxins /dibenzofurans and dioxin-like poly-chlorinated biphenyls congeners. (mdibl.org)
  • fibrosarcoma
  • In current practice, many tumors that were classified in older literature as fibrosarcoma, malignant fibrous histiocytoma, or hemangiopericytoma are now more reliably classified as other entities. (redorbit.com)
  • survival
  • Anaplastic histological features as high mitotic rate, microvascular proliferation and perinecrotic palisading tumor cells had no influence over survival [ 3 , 8 ]. (panafrican-med-journal.com)
  • distinct
  • A molecularly distinct entity, embryonal tumor with multilayered rosettes (ETMR), C19MC -altered, has been added, encompassing embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma. (cancer.gov)
  • residual
  • Postoperative MR images of the head and spine for 17 patients were reviewed for the presence of locally recurrent or residual tumor and disseminated neoplasm. (ajnr.org)
  • It is remarkable in that it has a documented spontaneous rate of resolution and is also one of the few tumors in which the surgical capsule can be violated and a good outcome might be achieved, even if residual tumor is left behind. (medscape.com)
  • cancerous
  • Nevoid basal cell carcinoma syndrome ( NBCCS ), also called Gorlin syndrome, is an inherited, multisystemic disorder that is associated with an increased risk of certain cancerous and noncancerous tumors. (invitae.com)
  • mutations
  • Up to 35% of patients may present with germline mutations and be prone to synchronous, multifocal tumors. (cancer.gov)
  • Fifteen tumors had homozygous deletions of one or more exons of the INI1 gene, and the other 14 tumors demonstrated mutations. (aacrjournals.org)
  • Although germ-line mutations in INI1 were not observed, the homozygous loss or inactivation of the INI1 gene is consistent with its function as a tumor suppressor gene. (aacrjournals.org)