2002 drug industry. Medical search. Frequent questions

This draft guidance supersedes the draft guidance for industry titled "Inhalational Anthrax (Post-Exposure) - Developing Antimicrobial Drugs," published in March 2002. (centerwatch.com)
FDA believes it is important to include veterinary oversight in the use of medically important antimicrobial drugs to ensure their appropriate and judicious use. (avma.org)
FDA believes that the judicious use of medically important antimicrobial drugs in the feed or water of food-producing animals needs the scientific and clinical training of a licensed veterinarian. (avma.org)

In 2002, then President Gloria Macapagal Arroyo asked the pharma industry for help in making available affordable drugs. (inquirer.net)
However, given the sheer number of analytical chromatography instruments in use throughout the pharma industry, the greening of analytical chromatography remains an important focus as well. (ddw-online.com)
Publication of the Process Validation Guidance by the U.S. Food and Drug Administration in January 2011 (FDA 2011) with its Stage 3 addressing "Continued Process Verification" has renewed Pharma and Biopharma's s interest in process monitoring. (pharmamanufacturing.com)
This alone is enough to explain why the pharma industry increasingly favours biotech-like specialty products versus the old blockbuster model. (pharmatimes.com)

Shortly after the 2002 draft guidance issued, the FDA amended its regulations to provide a regulatory mecha-nism to approve drugs and biological prod-ucts when human efficacy studies are not ethical or feasible. (centerwatch.com)
Bionorica just started to manufacture dronabinol, and according to personal communication, intends to manufacture a cannabis extract and to start with clinical research shortly (Grotenhermen 2002). (420magazine.com)

A prime concern is simply not having enough blockbuster drugs in the developmental pipeline. (areadevelopment.com)

Others court controversy -- like the song about John Walker Lindh, the 'American Taliban,' or the British drag queen who pokes fun at the entertainment industry's egocentric response to the attacks. (rferl.org)
One act at the Edinburgh Fringe, British drag queen Tina C, generated a lot of media coverage for her satire of the entertainment industry's response to 11 September. (rferl.org)
Angell disputes the industry's reputation as an "engine of innovation," arguing that the top U.S. drug makers spend 2.5 times as much on marketing and administration as they do research. (motherjones.com)
Another trend over the last several years is the industry's shift away from "blockbuster" drugs (chemistry-based drugs for broad patient populations) to promising new "specialized" products that are geared toward specific disorders and are increasingly biotech in design - that is, biologically derived, rather than chemically produced. (areadevelopment.com)
The National Retail Federation (NRF) is the world's largest retail trade association, with membership that comprises all retail formats and channels of distribution including department, specialty, discount, catalog, Internet, and independent stores, chain restaurants, drug stores and grocery stores, as well as the industry's key trading partners of retail goods and services. (cdc.gov)

The World Health Organization (WHO) has barred a life sciences industry association from participating in setting global standards protecting food and water supplies because its members have a financial stake in the outcome. (corpwatch.org)
GPhA became a powerful lobbying organization during Ms. Jaeger's tenure-a period which also corresponded to an increase in the retail generic dispensing rate (GDR) from about 40% in 2002 to more than 70% today. (drugchannels.net)

Every day Americans are subjected to a barrage of advertising by the pharmaceutical industry. (nybooks.com)

AHRP board members, Allen Jones and Dr. Stefan Kruszeuski, are prominently featured as the authorities who blew the whistle on (a) covert relationships between state mental health officials and TMAP, the pharmaceutical industry driven prescribing guidelines (Jones), and (b) about the abusive prescribing of toxic drug cocktails that have killed (Kreuszeuski). (ahrp.org)

Effectivness of Workplace Drug Prevention Policies: Does 'Zero Tolerance' Work? (ojp.gov)

LOS ANGELES, Aug. 25 - The attorney general of California sued 39 drug companies on Thursday, accusing them of bilking the state of hundreds of millions of dollars by overcharging for medicines. (corpwatch.org)
Switches occur when patients receive medicines formally designated as biosimilars, but may also occur after manufacturing process changes have occurred, if the process changes lead to structural modifications or changes in the impurity profile of the biologic drug [ 5 ]. (springer.com)
It was only during the Cheaper Medicines Act campaign in 2006, when then Health Secretary Francisco Duque III and Intellectual Property Office Director-General Adrian Cristobal Jr. explained that many of the well-known brands are, in fact, generic drugs, did the public understand that generics are not necessarily "inferior" if coming from a reputable company. (inquirer.net)
The pharmaceutical industry is showing not only increasing interest in synthetic modulators of the endogenous cannabinoid system, but also industry members are funding several clinical studies with cannabis whole plant extracts in Europe and Canada with the intention to develop approved cannabis based medicines. (420magazine.com)
Currently, it is responsible for the care of about 200 patients/day, offering vacancies for curricular internships for students in the Pharmacy course, it has become a reference in the manipulation of many drugs neglected by the pharmaceutical industry and provides access to medicines for low-income users playing an important social function. (bvsalud.org)

However the present Schedule I classification of cannabis and THC is an impediment to the pharmaceutical development of cannabinoid drugs becaused of the costly restrictions it places on research. (420magazine.com)

At the close of 2002, Complainant operated 4,087 retail and specialty pharmacies in 32 states and the District of Columbia. (wipo.int)
The costs of distributing and dispensing a traditional (non-specialty) generic drug far exceed the actual cost of the medicine, which is the opposite of brand-name drugs. (drugchannels.net)

The technological dynamics in the pharmaceutical R&D obliges companies to cope up with different competences and technologies outside their knowledge base and, of course, their boundaries ( GAMBARDELLA, 1995 GAMBARDELLA, A. Science and innovation: The US pharmaceutical industry during the 1980s. (scielo.br)
DE MATOS, 2016 DE MATOS, M.M. Changes in Innovation Dynamics of the Pharmaceutical Industry: A Study of the Interaction between Large pharmaceutical Companies and the Acquired Small Biotechnology Enterprises. (scielo.br)
compelling both to interact ( BAUMOL, 2002 BAUMOL, W.J. Entrepreneurship, Innovation and Growth: The David-Goliath Symbiosis. (scielo.br)

The high price of prescription drugs has put U.S. pharmaceutical companies in the news recently, but Dr. Marcia Angell argues that problems with the industry run even deeper. (motherjones.com)

The Food and Drug Administration yesterday released a warning letter it sent to the Guidant Corporation, restricting the ability of the company to win approval for some new medical products. (corpwatch.org)
Yet what Clark and others are doing is technically illegal, since the U.S. forbids the import of prescription drugs by anyone other than the original U.S. manufacturer, and even then only when the drugs meet all the approval requirements of the U.S. Food and Drug Administration (FDA). (cnn.com)
The December 2004 Food and Drug Administration (FDA) approval of clofarabine (Clolar, Genzyme) for refractory pediatric acute lymphoblastic leukemia was a milestone in the history of pediatric cancer drug development. (aacrjournals.org)
Historically, the US Food and Drug Administration (FDA) has had a pregnancy category labeling system that uses letters- A, B, C, D, and X -to convey reproductive and lactation safety. (psychiatrist.com)
On January 26, 2004, the US Food and Drug Administration (FDA) announced new rules to further strengthen existing protection against BSE, including banning a wide range of bovine material from human food ( United States Department of Health and Human Services, Expanded "Mad Cow" Safeguards Announced To Strengthen Existing Firewalls Against BSE Transmission ). (medscape.com)
Consumers and lawmakers pushing for cheaper alternatives to the EpiPen, an antidote for life-threatening allergic reactions, and other high-priced drugs are seeking answers about a stubborn backlog of generic drug applications at the Food and Drug Administration. (wfdd.org)
Ahead, Idec faced the daunting task of developing an effective drug and shepherding it through the numerous regulatory stages required to gain approval from the U.S. Food and Drug Administration ( FDA ). (encyclopedia.com)
We may soon find out, if W. David Hager becomes chairman of the powerful Food and Drug Administration panel on women's health policy. (tampabay.com)
Despite these mixed results with sunitinib, in 2017, the U.S. Food and Drug Administration (FDA) granted approval for adjuvant sunitinib in patients with renal cell carcinoma. (ascopost.com)
The same concept has been used by the US Food and Drug Administration (FDA) to establish ``thresholds of regulation'' for indi- rect food additives and adopted by the Joint FAO/WHO Expert Committee on Food Additives for flavoring substances. (cdc.gov)

The NIOSH Hazardous Drug Committee has reviewed all new FDA drug approvals and new drug warnings for the period January 2014 through December 2015. (cdc.gov)
The committee reviewed 73 new drug approvals and 198 drugs with new warnings. (cdc.gov)

2002]. OELs in this range are typically established for potent or toxic drugs in the pharmaceutical industry. (cdc.gov)
Liquid chromatography, most commonly used for purification in the pharmaceutical industry (10), typically employs modified silica or polymer particles as a solid phase, with water, organic solvents, or a mixture of the two as a mobile phase. (ddw-online.com)
This is a major exception, as approval of new cancer drugs for pediatric patients is typically an afterthought to their development and approval for treating adult cancers. (aacrjournals.org)
When new drugs become approved, systematic human pregnancy data are typically nonexistent. (psychiatrist.com)

The importance of such information is highlighted by the fact that stability testing data are required for a new drug or formulation to receive regulatory approval. (pittcon.org)
CVM's Office of New Animal Drug Evaluation has been proactive in helping pharmaceutical sponsors meet the statutory and regulatory standards that provide safe, effective, quality-manufactured, and properly labeled animal drugs. (avma.org)
These collections are an important tool for researchers, lawyers, journalists, advocates and the general public as they expose industry tactics around marketing campaigns, regulatory strategies, and public health policy formulation. (ucsf.edu)

In 1995 the company drew negative attention when one of its home care employees was arrested while buying illegal drugs, and press reports focused on the fact that since the company does not provide medical services, its employees are not required to be certified and may not be closely supervised. (wikipedia.org)

This draft guidance describes approaches for the designs of the animal model efficacy studies and recognizes that drug development for the sole indication of prophylaxis of inhalational anthrax is pos-sible. (centerwatch.com)
The 2002 draft stated that drugs for the prophylaxis of inhalational anthrax would be approved under the accelerated approval regulations unless the drug already carried an anthrax indication. (centerwatch.com)
A rare occurrence, it represented approval of a new cancer drug for a pediatric cancer indication without prior approval for an adult cancer indication. (aacrjournals.org)

On the 20th anniversary of its founding, April 26, 2002, the company name officially changed to Griswold Home Care. (wikipedia.org)
The 15-emmployee company just "came out" officially, at a pharmaceutical industry conference in Boston in late April, Cunningham says. (wraltechwire.com)

David Franklin, the drug company whistle-blower who has sparked federal and state investigations into the marketing of the top-selling drug Neurontin, said yesterday that he and his former colleagues engaged in a series of inappropriate tactics, including misleading doctors to persuade them to prescribe the drug for unapproved uses. (corpwatch.org)
Not only do these patients go without needed treatment but their doctors sometimes wrongly conclude that the drugs they prescribed haven't worked and prescribe yet others-thus compounding the problem. (nybooks.com)
The company "obtained a patent on the idea of combining Prilosec with antibiotics, then argued that a generic drug would infringe on that patent because doctors might prescribe it with an antibiotic. (motherjones.com)

Of those 30 drugs, only 15 acquired any labeling for pediatric use during that same 55-year period ( 1, 2 ). (aacrjournals.org)
This disparity in the number of oncology drugs labeled for use in adults versus children is a manifestation of the many challenges faced in pediatric cancer drug development. (aacrjournals.org)
So, why has pediatric drug development been the poor stepchild of cancer drug development? (aacrjournals.org)
What are the major challenges currently confronting pediatric cancer drug development? (aacrjournals.org)
How these factors intermesh to constrain new pediatric cancer drug development is outlined below. (aacrjournals.org)
With the average cost of research and development to bring one drug to market at $802 million and given that 1 in 1,000 new compounds that enter preclinical testing ever make it to human testing and only 1 in 5 agents that enter human trials receive FDA approval ( 4, 5 ), it is little wonder that pharmaceutical companies would hesitate to invest in pediatric cancer treatments. (aacrjournals.org)
This Viewpoint lists the top 3 pediatric drugs and product shortages, considers the federal government's and manufacturers' ethical duty to protect children, reviews the causes for the shortages, and suggests policy changes that could help fill in the gap. (bvsalud.org)

Americans now spend a staggering $200 billion a year on prescription drugs, and that figure is growing at a rate of about 12 percent a year (down from a high of 18 percent in 1999). (nybooks.com)

Teaching our kids to "just say no" may keep them off street drugs, but what do we do when the schools, government, and pharmaceutical companies partner to push another kind of dangerous drug? (ahrp.org)
Pharmaceutical companies say that the high price of drugs reflects the cost of R&D. What do you make of that argument? (motherjones.com)
In 2002, the top 10 American [pharmaceutical] companies in the Fortune 500 made 17 percent of their sales in profits, whereas they spent only 14 percent on R&D. The median for the other Fortune 500 companies was between 3 and 4 percent of sales. (motherjones.com)

Therefore, stability testing is a routine procedure performed on drug substances and products at each stage of product development so the company can be certain that the quality of their products will endure throughout the time they are available for supply to patients. (pittcon.org)
The International Conference on Harmonization (ICH) has long recognized the importance of stability testing in drug development and wants drugs to be made safer by having a well-defined stability profile. (pittcon.org)
The most imperatives for academia and industry collaboration were found to be: ensuring research findings solve socio-economic and development problems, the intermittent collapse of buildings, support for the local industries to produce quality materials locally to feed the construction industry, proper contract documentations and administration. (scirp.org)
These health-based limits are used to sup- impurity and degradant levels in drugs ( ICH, 1997a, port both occupational health and quality programs in 2002a,b,c, 2003 ), with acceptable amounts for residual pharmaceutical research, development and manufactur- solvents in pharmaceuticals, so-called ``permitted daily ing operations. (cdc.gov)

This study seeks to establish the imperative of academia and industry collaboration in building research in Ghana. (scirp.org)
This research would bring to light the urgent issues in the construction industry that calls for greater collaboration between the academia and industry in Ghana. (scirp.org)
Dok Yen, D. , Adinyira, E. and Dauda, A. (2018) Imperatives for Academia-Industry Collaboration in Building Construction Research in Ghana. (scirp.org)
The Ghanaian construction industry is faced with many challenges with some of the reasons being due to lack of formal collaboration between the academia and industry in the area of construction research. (scirp.org)
The objective of this research seeks to establish the imperatives for academia industry collaborative research in the construction industry which would go a long way to foster the need for stronger construction research collaboration between the academia and industry in Ghana. (scirp.org)
The Food Industry Documents Archive was created in 2018 in collaboration with the UCSF Philip R. Lee Institute for Health Policy Studies. (ucsf.edu)
The Chemical Industry Documents Archive was created in 2017 in collaboration with the UCSF Program on Reproductive Health and the Environment (PRHE) . (ucsf.edu)

S.S.R.I. stands for selective serotonin reuptake inhibitor, referring to the fact that these drugs increase levels of the neurotransmitter serotonin, a chemical in the brain involved in regulating moods. (mindfreedom.org)
A new chemical entity is a drug that contains no active moiety that has been approved by the FDA in any other application submitted under the Federal Food, Drug, and Cosmetic Act. (avma.org)
The CSSK is the first so-called biotherapeutic drug developed in India- meaning it entailed the use of antibodies, proteins and enzymes, unlike conventional chemical drugs. (livemint.com)
From 2002 to 2006, the industry commercialized 43 percent fewer new chemical-based drugs than it did in the previous five years, despite more than doubling its R&D spending. (areadevelopment.com)
Ludwig Kofler especially focused on microscopic and micro-chemical investigations of natural and synthetic drug substances. (uibk.ac.at)
IDL currently brings together materials created by the tobacco, drug, food, and chemical industries. (ucsf.edu)

The campaign was made more complicated because the Bureau of Food and Drugs at the time did not have enough resources to ensure that only good quality generics were able to enter the country. (inquirer.net)
The EMA along with the European Commission, which handles approval of marketing materials, are approving generics and brand-name drugs in about a year on average, according to the EMA. (wfdd.org)
But he stressed that the FDA pushes pending applications for drugs with no current generics to the front of the line and approved 580 generics in 2015, a record for the agency and 40 percent more than in 2014. (wfdd.org)
Retail GDR will exceed 80% within two years, so generics represent the future of the pharmaceutical industry. (drugchannels.net)

The decision by the veterinarian to use a specific approved drug or combination drug is based on factors such as the mode of antibacterial action, drug distribution in specific tissues, and the duration of effective drug levels at the site of infection. (avma.org)
In addition, animal-associated infections (caused by, for example, Toxoplasma gondii , Listeria monocytogenes ) have been reported in people at increased risk because of deficiencies in the normal immune response as a result of immunosuppressive drugs, cancer or HIV infection. (who.int)

A psychiatrist who has taken thousands of dollars in psychiatric drug company pay-offs to present promotional speeches about their products exposes some of the techniques, and promises never to behave that way again. (mindfreedom.org)
What makes this more than just a story about influence-peddling to boost profits, of course, is the harm psychiatric drugs can do to the intended users, in this case, our nation's children. (ahrp.org)

To provide healthcare workers and healthcare facilities information on identifying hazardous drugs so that proper handling can be performed to reduce worker exposures. (cdc.gov)
The drug industry has been at the vanguard of the healthcare revolution that has powered improved life expectancy over the past 70-odd years, but that does not automatically make it a good future investment. (pharmatimes.com)

In 2002, while still known as Special Care, the company had 5 offices in the Philadelphia area run out of the corporate offices, with offices elsewhere operated as franchises. (wikipedia.org)
2 As a spokeswoman for one company explained, "Price increases are not uncommon in the industry and this allows us to be able to invest in R&D." 3 In 2002, the average price of the fifty drugs most used by senior citizens was nearly $1,500 for a year's supply. (nybooks.com)
In 2002, when generic drugs were judged "inferior, substandard quality" and "pang mahirap" by many, RiteMed was launched as a proudly generic company. (inquirer.net)
Back in 1992, a pharmaceutical company sales colleague of David Cunningham's approached him and said, "I had a dream you came up with an idea to get rid of cases of drug samples and still have samples. (wraltechwire.com)
The company agreed to pay the NIH only 0.5% in royalties for the drug. (motherjones.com)
The SmartScreen Consortium will transfer cutting edge Nuclear Magnetic Resonance technology for drug screening and drug design from the Host (UNIFRANMR) to three Industrial Partners, a large pharmaceutical company and a start-up company. (europa.eu)
The company was founded in San Francisco to develop and to commercialize drugs to treat immune system cancers and autoimmune and inflammatory diseases, a costly, time-consuming, and risky undertaking for a start-up biotechnology company. (encyclopedia.com)

When Medicare was enacted in 1965, people took far fewer prescription drugs and they were cheap. (nybooks.com)

His talks were on Neurontin, a drug that was approved for epilepsy but that my friend had found helpful for bipolar disorder in his practice. (mindfreedom.org)

Hence, poor aqueous solubility has become the leading hurdle for formulation, and scientists are concerned in improving oral delivery of insoluble drug candidates. (dovepress.com)
Nowadays, crystalline nanosuspensions (nanocrystals) are considered a valuable formulation for drugs that have a poor dissolution rate and/or aqueous solubility. (dovepress.com)

Although originally invented by Tswett as a purification technique, chromatography has evolved into one of the most widely used analytical technologies in the pharmaceutical industry. (ddw-online.com)
It has a powerful partner in the FDA, which over the past year has conducted widely publicized seizures of prescription drugs shipped into the U.S. from Canada, Mexico and elsewhere that it maintains could be harmful to consumers. (cnn.com)
This white to slight yellowish crystalline powder is very soluble in water, hygroscopic and has been widely used in industry and construction. (who.int)

The Truth Tobacco Industry Documents (TTID) archive (formerly known as the Legacy Tobacco Documents Library) was created in 2002 and is our largest archive with over 14 million items. (ucsf.edu)
TTID was built to house and provide permanent access to tobacco industry internal corporate documents produced during litigation between US States and the seven major tobacco industry organizations and other sources. (ucsf.edu)
Directive 2002/10, excise duties cise was just 12 euro in Latvia, 21 cline in overall tobacco use levied on cigarettes should account euro in Lithuania, and 26 euro in (Chaloupka, Straif, & Leon, 2011). (who.int)
Cases of tobacco taxation policy in pean Commission database (Euro- consumption in the EU were com- the Baltic countries were presented pean Commission, 2012) and re- missioned by the Philip Morris In- by the tobacco industry sponsored ports as well as from the national ternational. (who.int)
The industries must inform the type of tobacco used, the constituents and additives used in the manufacturing of each brand. (who.int)

Mixed in with the pitches for a particular drug-usually featuring beautiful people enjoying themselves in the great outdoors-is a more general message. (nybooks.com)

The guidance provides recommendations on maintaining a balance between eliminating the collection of data that will not be useful and collecting sufficient data to allow adequate characterization of the safety profile of a drug in scenarios where selec-tive safety data collection is appropriate. (centerwatch.com)
In the February 16, 2016 Federal Regis-ter , the FDA announced the availability of a draft guidance for industry titled "Anthrax: Developing Drugs for Prophylaxis of Inha-lational Anthrax. (centerwatch.com)
The purpose of this draft guidance is to assist sponsors in the devel-opment of new drugs to be administered to persons who have inhaled Bacillus anthracis spores, but who have not yet manifested clini-cal evidence of disease, to prevent develop-ment of inhalational anthrax disease. (centerwatch.com)
This draft guidance states that drugs developed for prophylaxis of inhalational anthrax will be considered for approval under the animal rule regulations. (centerwatch.com)
In December 2013, FDA rolled out Guidance for Industry No. 213 asking drug sponsors to align with GFI No. 209, FDA's judicious use principles for antimicrobials. (avma.org)

The increase in drug spending reflects, in almost equal parts, the facts that people are taking a lot more drugs than they used to, that those drugs are more likely to be expensive new ones instead of older, cheaper ones, and that the prices of the most heavily prescribed drugs are routinely jacked up, sometimes several times a year. (nybooks.com)
However, reducing the evidence to a letter reflects neither the quantity or quality of the data nor how a particular medication compares to other drugs used for similar indications. (psychiatrist.com)

One of them is Lipitor, the expensive, heavily marketed cholesterol-lowering drug developed by Pfizer. (cnn.com)

G.O.P. Congressman Dan Burton who represents Indiana, where drug giant Eli Lilly employs thousands of voters has accused the industry of "raping the American people. (cnn.com)

NIOSH identified 44 drugs as potentially hazardous for review by the peer reviewers. (cdc.gov)
In evaluating mutagenicity for potentially hazardous drugs, responses from multiple test systems are needed before precautions can be required for handling such agents. (cdc.gov)
One covert laboratory dismantled there last year was an industrial-scale facility set up to produce ketamine and potentially other drugs, the report said. (metro.us)

A Congressional investigation of the money that drug companies give as supposed educational grants has found that the payments are growing rapidly and are sometimes steered by marketing executives to doctors and groups who push unapproved uses of drugs. (corpwatch.org)
In February, JAVMA News talked with the director of the Food and Drug Administration's Center for Veterinary Medicine, Dr. Bernadette Dunham, about drug issues and the investigation into adverse health effects associated with jerky pet treats. (avma.org)
The UCSF Industry Documents Library (IDL) is a portal to aid investigation about cross-industry corporate practices that are detrimental to public health. (ucsf.edu)

TeenScreen has a false-positive rate of 84%-thereby ensuring that the market for psychotropic drugs will expand far and wide beyond children with actual mental abnormalities who might conceivably be helped. (ahrp.org)
The majority of the new products the industry puts out, says Angell, are "me-too" drugs: ones that are almost identical to current treatments but "no better than drugs already on the market to treat the same condition. (motherjones.com)
She discusses Prisolec maker Astra-Zeneca, which filed multiple lawsuits against generic drug makers to prevent them from entering the market when the company's exclusive marketing rights expired. (motherjones.com)
If and when the drug reaches the market, it could offer an affordable alternative to expensive thrombolytic drugs used to treat patients of myocardial infarction or heart attacks, and other severe heart conditions like deep vein thrombosis. (livemint.com)
Chennai-based Shasun Chemicals and Drugs in 2009 launched recombinant streptokinase for around $50 per dose in the open market. (livemint.com)
Idec began the long and difficult journey of taking a drug from discovery to market in 1985. (encyclopedia.com)
It takes about $800 million and 12 to 15 years to bring a new drug to market, according to the Pharmaceutical Research and Manufacturers of America. (areadevelopment.com)
Another worry is the high number of recent or pending patent expirations, which will allow other companies to flood the market with less expensive generic drugs. (areadevelopment.com)
IMS Health, a market research firm that tracks pharmaceutical sales, projects worldwide drug sales in 2008 will grow 5 to 6 percent and that U.S. and top European markets will grow about 4 to 5 percent. (areadevelopment.com)
In Egypt, atenolol is significant gastrointestinal, cardiac, dominated by the local generic industry, marketed as Tenormin (Innovator), renal, hepatic or haematological abnor- which has become a major export hub manufactured under license, and three malities and whose clinical laboratory for the regional market [2,3]. (who.int)

All drugs have toxic side effects, but some exhibit toxicity at low doses. (cdc.gov)

Angell's goal is to reform the industry, whose top ten companies make more in profits than the other Fortune 500 companies combined. (motherjones.com)
Until last year, [they were] the number one industry in the U.S. in terms of profits, and by a long shot. (motherjones.com)
Ms. Jaeger's background implies that she understands the true economics of the PBM business today, such as the fact that the majority of a PBM's profits come from dispensing generic drugs from their own mail-order pharmacies while retail network spreads are a comparatively small source of profits. (drugchannels.net)

Nanosuspensions consist of stabilized submicron sized crystalline drug particles in liquid medium, usually water. (dovepress.com)

We coded creatives for manifest content and adherence to federal regulations and industry codes. (cdc.gov)
Author Manuscript ads as noncompliant with federal regulations and 38 with industry codes. (cdc.gov)

ironically, older drugs that have received years of study including sizable numbers of pregnant women followed prospectively, with even inconsistent reports of worrisome outcomes, may be placed in a category that strikes fear in patient and clinician hearts-notably the C or D that most psychotropics have received, even if the risk/benefit for a particular patient is in favor of using the drug. (psychiatrist.com)
Work on the drug began seven years ago under a partnership between the CSIR's Institute of Microbial Technology (IMTECH), Chandigarh, and Nostrum Pharmaceuticals LLC of the US. (livemint.com)
Many patients were in the dark about EpiPen price increases until insurers started shifting more of the cost onto consumers a few years ago, and getting approval for a generic that's both a drug and a device is more complicated than getting approval for a drug alone, he said. (wfdd.org)
The 1.008 billion tablets - which would weigh about 91 tons altogether - were part of a regionwide haul of almost 172 tons of methamphetamine in all forms, and was seven times higher than the amount seized 10 years earlier, the U.N. Office on Drugs and Crime said in a report. (metro.us)
Industry experts have estimated that generic competition will wipe out more than $60 billion from U.S. industry sales over the next five years, as more than three dozen drugs lose patent protection. (areadevelopment.com)

It already claims the top 12 companies in the pharmaceutical industry as clients. (wraltechwire.com)
That's the way we can speak with our money to the drug companies to treat us more fairly. (cnn.com)
Individual scientists, academic labs and small drug firms are currently the main promoters of pharmaceutical research, because large drug companies have traditionally been reserved with regard to the cost and the political problems associated with marketing marijuana as medicine. (420magazine.com)
In her new book, "The Truth About Drug Companies," the former editor of the New England Journal of Medicine contends that the industry has become a "vast marketing machine" which produces few innovative drugs and is dependent on monopoly rights and public-sponsored research. (motherjones.com)
At least a third of the drugs marketed by industry leaders were discovered by universities or small biotech companies, writes Angell, but they're sold to the public at inflated prices. (motherjones.com)
Drug companies face further pressure from large private insurers that want them to lower prices. (areadevelopment.com)
As a result, the economic interests of companies within the U.S drug channel-pharmacies, wholesalers, and PBMs-are diverging from brand-name drug manufacturers. (drugchannels.net)

Angell writes that around 75% of new drugs approved by the FDA are me-too drugs, such as more pills for heartburn or allergies that can be less effective than current drugs, as long as they're more effective than a placebo. (motherjones.com)

Intriguingly, GPhA often aligned with the Pharmaceutical Care Management Association (PCMA), which represents the pharmacy benefit management (PBM) industry. (drugchannels.net)
NRF represents an industry with more than 1.6 million U.S. retail establishments, more than 24 million employees -about one in five American work ersand 2005 sales of $4.4 trillion. (cdc.gov)
As the industry umbrella group, NRF also represents more than 100 state, national, and international retail associations. (cdc.gov)

By the end of 2002, the nutritional situation had improved, but with an estimated four million people displaced, a destroyed infrastructure, a landscape littered with millions of land mines (7 aid workers and patients, including 4 MSF staff, were killed in a landmine accident in December), inadequate mine-clearing activities, and continuing government intransigence, the desperate struggle for Angolans is far from over. (doctorswithoutborders.org)
One of Asia's biggest-ever drug busts was made in Laos last October, with police there seizing more than 55.6 million methamphetamine pills in a single raid. (metro.us)

In his State of the Union address last week, President Bush hailed the passage of the Medicare bill that will give seniors "the modern medicine they deserve" and touted the new drug-discount card that the Administration says will save them 10% to 25% on pharmaceuticals. (cnn.com)
An approved New Animal Drug Application ensures the veterinarian is providing quality medicine to patients. (avma.org)
As of 2002, the Pharmaceutical Care extension projects started to guarantee a rational and safe pharmacotherapy for the medicine users. (bvsalud.org)

We are requesting that as a peer reviewer, you review the list of drugs that NIOSH suggests be added to the list or not added to the list and provide your evaluations and comments on the Word document provided. (cdc.gov)

Drug Channels reaches an engaged, loyal and growing audience of more than 75,000 subscribers and followers. (drugchannels.net)

However, Burger especially focused on the area of drug preformulation, thus contributing with practical and theoretical papers to a better understanding of the importance of physicochemical properties of drug substances. (uibk.ac.at)

The effort to develop an affordable, safe clot-busting drug in India dates back to 2002 when Cadila Pharmaceuticals Ltd commercialized the first clot- buster drug and sold it for about $20 per dose. (livemint.com)
Other off-patent drugs with rising prices and no generic competition have also drawn scrutiny, including Turing Pharmaceuticals' Daraprim, for toxoplasmosis, and Valeant's cardiovascular drugs Isuprel and Nitropress. (wfdd.org)

But generic drugs turn pharmaceutical channel economics upside down. (drugchannels.net)
ABSTRACT Concerns have been raised regarding the postmarketing quality of generic drugs. (who.int)

On average, name-brand prescription drugs in Canada cost an estimated 40% less than they do in the U.S. (cnn.com)

On a trip last November, Clark did even better than that, buying a six-month supply of medications for a little more than $1,000, a cache that she estimates would have cost about $3,000 in Maine for the same drugs. (cnn.com)
She cites Taxol, the cancer drug discovered by the National Institutes of Health, but sold by Bristol-Myers Squibb for $20,000 a year, reportedly 20 times the manufacturing cost. (motherjones.com)
Drugs and Society: The True Cost to You! (ojp.gov)
According to Douglas, when he first worked in the region in 2002-2007, a meth tablet cost five to six times what it costs now. (metro.us)

All noxious and unintended responses to a medicinal product related to any dose should be considered adverse drug reactions (from US FDA Guideline for Industry, Clinical Safety Data Management: Definitions and Standards for Expedited Reporting). (cdc.gov)

Mossinghoff is a former assistant secretary of commerce, commissioner of patents, and president of the American Pharmaceutical industry trade group, PhRMA. (wraltechwire.com)

He adds that manufacturers like it because it pulls everything through the normal distribution chain that delivers drugs to pharmacists and does not require special packaging or bookkeeping. (wraltechwire.com)
Drug Channels delivers timely analysis and provocative opinions from Adam J. Fein, Ph.D., the country's foremost expert on pharmaceutical economics and the drug distribution system. (drugchannels.net)

The FDA has also been slow in approving new drugs - a cautious reaction, no doubt, to Merck's recall of Vioxx in 2004. (areadevelopment.com)

Antimicrobial Drugs3

Pharma4

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Developmental1

Industry's5

ORGANIZATION2

Advertising by the pharmaceutical industry1

Guidelines1

Workplace1

Medicines5

Classification1

Specialty2

Innovation3

Marcia Angell1

Food and Drug Admin10

Approvals2

Typically4

Regulatory3

19951

Indication3

Officially2

Prescribe3

Pediatric7

19991

Pharmaceutical companies3

Development4

Collaboration7

Chemical6

Generics4

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Particles1

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Years5

Companies7

Long1

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Medicine3

Review1

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Pharmaceuticals2

Generic drugs2

Average1

Cost4

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