2 specifically inhibited gpcr. Medical search. Frequent questions

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Anatomy12

HEK293 Cells COS Cells Cell Line CHO Cells Cell Membrane Cells, Cultured Clathrin-Coated Vesicles Neurons Endosomes Intracellular Space Brain NIH 3T3 Cells

Organisms9

Cricetinae Cricetulus Cercopithecus aethiops Mice, Knockout Cattle Takifugu Mice, Inbred C57BL Mice, Transgenic Drosophila melanogaster

Chemicals and Drugs150

Receptors, G-Protein-Coupled Ligands Receptors, Adrenergic, beta-2 G-Protein-Coupled Receptor Kinase 2 Rhodopsin Relaxin Receptors, Peptide GTP-Binding Proteins RGS Proteins G-Protein-Coupled Receptor Kinases GTP-Binding Protein alpha Subunits Heterotrimeric GTP-Binding Proteins GTP-Binding Protein alpha Subunits, Gi-Go Adrenergic beta-2 Receptor Agonists GTP-Binding Protein alpha Subunits, Gq-G11 Adrenergic beta-2 Receptor Antagonists beta-Adrenergic Receptor Kinases Receptor, Adenosine A2A Cyclic AMP G-Protein-Coupled Receptor Kinase 3 Opsins Lysophospholipids Receptors, Cell Surface GTP-Binding Protein beta Subunits G-Protein-Coupled Receptor Kinase 5 GTP-Binding Protein gamma Subunits Calcitonin Receptor-Like Protein GTP-Binding Protein alpha Subunits, Gs Class Ib Phosphatidylinositol 3-Kinase Receptors, Lysophosphatidic Acid Receptor, PAR-1 Recombinant Fusion Proteins GTP-Binding Protein alpha Subunits, G12-G13 Receptors, Mating Factor Receptors, Formyl Peptide Guanosine 5'-O-(3-Thiotriphosphate)Receptors, Serotonin, 5-HT4 Receptor, Melatonin, MT1 Receptors, Adrenergic, beta-1 Receptors, LHRH Receptors, Lipoxin Receptor, Muscarinic M3 GTP-Binding Protein Regulators Receptors, Vasopressin Cyclic AMP-Dependent Protein Kinases Receptors, Lysophospholipid Adenosine A2 Receptor Antagonists Pertussis Toxin Sphingosine Receptor, Cannabinoid, CB1 Receptor, Muscarinic M1 Receptor, Muscarinic M2 Adenosine A2 Receptor Agonists Dynamins Receptors, GABA-B Receptors, Neurotensin Receptor, Melatonin, MT2 Receptor, Parathyroid Hormone, Type 1 Receptors, Leukotriene B4 Single-Domain Antibodies G-Protein-Coupled Receptor Kinase 1 Receptors, Adrenergic, alpha-2 Calcium Extracellular Signal-Regulated MAP Kinases Membrane Proteins Receptor Activity-Modifying Protein 2 Receptors, CXCR4 Green Fluorescent Proteins Receptors, Chemokine Inositol Phosphates Receptors, Metabotropic Glutamate Receptors, Calcitonin S-Nitrosothiols Neuropeptides Phospholipase C beta Receptor, Melanocortin, Type 4 Receptors, Opioid Peptides Receptors, Dopamine D2 Receptors, Lysosphingolipid Protein Subunits Receptors, Neuropeptide Receptor, Melanocortin, Type 3 Receptor, Cannabinoid, CB2 Thyronines G Protein-Coupled Inwardly-Rectifying Potassium Channels Fenoterol RNA, Small Interfering Receptors, Somatostatin src-Family Kinases Receptor Activity-Modifying Protein 1 Dendrimers Multiprotein Complexes Mutant Proteins Pheromones Receptor, Epidermal Growth Factor Serotonin 5-HT4 Receptor Agonists Receptors, Thyrotropin-Releasing Hormone Adenylate Cyclase Transducin Receptors, Muscarinic Propanolamines Receptors, Oxytocin RNA, Messenger Bradykinin Luminescent Proteins Clathrin Receptor, Angiotensin, Type 1 Receptors, Opioid, delta Receptors, Calcitonin Gene-Related Peptide Receptors, Thromboxane A2, Prostaglandin H2 Adaptor Protein Complex 2 Nerve Tissue Proteins Isoproterenol GTPase-Activating Proteins Mitogen-Activated Protein Kinases Receptors, Neuropeptide Y Receptors, Dopamine D3 Recombinant Proteins Receptors, Adrenergic, alpha-1 MAP Kinase Kinase 5 DNA, Complementary Peptide Fragments Phosphatidylinositol 3-Kinases Receptors, Odorant Mitogen-Activated Protein Kinase 3 Receptor, Adenosine A1 Receptors, Ghrelin Adrenergic Agonists Receptors, Melanocortin Neurotensin Protein Kinase C Frizzled Receptors Small Molecule Libraries Clozapine Proteins Mitogen-Activated Protein Kinase 7 Receptors, Glucagon Cysteine Receptors, Opioid, mu Protein Isoforms Mitogen-Activated Protein Kinase 1 Receptor, Bradykinin B2 Receptors, Opioid, kappa Muscarinic Agonists Tyrphostins Drosophila Proteins Oligopeptides Adrenergic beta-Agonists Receptors, Serotonin

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Models, Molecular Drug Design Drug Discovery Fluorescence Resonance Energy Transfer Radioligand Assay Models, Biological Sequence Alignment Molecular Docking Simulation Transfection Bioluminescence Resonance Energy Transfer Techniques Crystallography, X-Ray Molecular Dynamics Simulation Mutagenesis, Site-Directed Sequence Analysis, Protein Immunoprecipitation Amino Acid Substitution Cloning, Molecular Microscopy, Fluorescence Blotting, Western Microscopy, Confocal Drug Evaluation, Preclinical Molecular Targeted Therapy Protein Engineering Dendrimers Binding, Competitive Reverse Transcriptase Polymerase Chain Reaction Biosensing Techniques Nuclear Magnetic Resonance, Biomolecular Protein Interaction Mapping Gene Knockdown Techniques

Phenomena and Processes52

Signal Transduction Protein Binding Amino Acid Sequence Protein Structure, Tertiary Protein Conformation Protein Transport Protein Multimerization Drug Inverse Agonism Fluorescence Resonance Energy Transfer Phosphorylation Binding Sites Protein Structure, Secondary Endocytosis Dimerization Sequence Homology, Amino Acid Receptor Cross-Talk Mutation Structural Homology, Protein Transfection Allosteric Regulation Amino Acid Motifs Structure-Activity Relationship Allosteric Site Molecular Dynamics Simulation Chemotaxis Protein Stability Light Signal Transduction Enzyme Activation Amino Acid Substitution MAP Kinase Signaling System Gene Expression Regulation Molecular Conformation Protein Structure, Quaternary Dose-Response Relationship, Drug Phylogeny Lipoylation Kinetics Conserved Sequence Calcium Signaling Mutagenesis Binding, Competitive Molecular Structure Evolution, Molecular Protein Interaction Domains and Motifs Algorithms Tissue Distribution Down-Regulation Time Factors Organ Specificity Cell Movement Gene Expression Base Sequence

Disciplines and Occupations3

Drug Design Drug Discovery Computational Biology

Technology, Industry, Agriculture1

Information Science9

Amino Acid Sequence Molecular Sequence Data Molecular Docking Simulation Molecular Dynamics Simulation Phylogeny Databases, Protein Algorithms Base Sequence Computer Simulation

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science

Receptors, G-Protein-Coupled Ligands Receptors, Adrenergic, beta-2 Signal Transduction G-Protein-Coupled Receptor Kinase 2 Rhodopsin Relaxin Receptors, Peptide GTP-Binding Proteins RGS Proteins G-Protein-Coupled Receptor Kinases GTP-Binding Protein alpha Subunits Protein Binding Heterotrimeric GTP-Binding Proteins Amino Acid Sequence Models, Molecular HEK293 Cells GTP-Binding Protein alpha Subunits, Gi-Go Molecular Sequence Data Adrenergic beta-2 Receptor Agonists GTP-Binding Protein alpha Subunits, Gq-G11 Adrenergic beta-2 Receptor Antagonists COS Cells beta-Adrenergic Receptor Kinases Cell Line Protein Structure, Tertiary Protein Conformation Receptor, Adenosine A2A Protein Transport Drug Design Protein Multimerization Cyclic AMP G-Protein-Coupled Receptor Kinase 3 Opsins Lysophospholipids Receptors, Cell Surface Drug Discovery GTP-Binding Protein beta Subunits CHO Cells G-Protein-Coupled Receptor Kinase 5 Drug Inverse Agonism GTP-Binding Protein gamma Subunits Fluorescence Resonance Energy Transfer Calcitonin Receptor-Like Protein Radioligand Assay GTP-Binding Protein alpha Subunits, Gs Class Ib Phosphatidylinositol 3-Kinase Phosphorylation Cell Membrane Cricetinae Binding Sites Protein Structure, Secondary Endocytosis Models, Biological Receptors, Lysophosphatidic Acid Dimerization Receptor, PAR-1 Recombinant Fusion Proteins Cricetulus Cercopithecus aethiops GTP-Binding Protein alpha Subunits, G12-G13 Sequence Alignment Molecular Docking Simulation Sequence Homology, Amino Acid Receptors, Mating Factor Receptors, Formyl Peptide Receptor Cross-Talk Guanosine 5'-O-(3-Thiotriphosphate)Mutation Structural Homology, Protein Receptors, Serotonin, 5-HT4 Receptor, Melatonin, MT1 Transfection Allosteric Regulation Amino Acid Motifs Receptors, Adrenergic, beta-1 Bioluminescence Resonance Energy Transfer Techniques Receptors, LHRH Structure-Activity Relationship Receptors, Lipoxin Crystallography, X-Ray Receptor, Muscarinic M3 Allosteric Site GTP-Binding Protein Regulators Cells, Cultured Receptors, Vasopressin Cyclic AMP-Dependent Protein Kinases Receptors, Lysophospholipid Adenosine A2 Receptor Antagonists Pertussis Toxin Sphingosine Receptor, Cannabinoid, CB1 Molecular Dynamics Simulation Receptor, Muscarinic M1 Chemotaxis Receptor, Muscarinic M2 Adenosine A2 Receptor Agonists Dynamins Mutagenesis, Site-Directed Receptors, GABA-B

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