• Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid (and a lecithin) consisting of two C16 palmitic acid groups attached to a phosphatidylcholine head-group. (wikipedia.org)
  • Among the phospholipids, the most prevalent one is phosphatidylcholine (PC, or lecithin) (70-85%), which in turn is the basis of a pool of similar diacylphophatidylcholines of which 50% is dipalmitoylphosphatidylcholine or DPPC. (wikipedia.org)
  • More specifically, it has been found that phosphatidylcholine (PC) is the most abundant phospholipid (70%-85%), and that PC is primarily present as dipalmitoylphosphatidylcholine (DPPC). (wikipedia.org)
  • Dipalmitoylphosphatidylcholine (DPPC) provided additional stability for AP-MWCNTs in epithelial growth medium (BEGM). (cdc.gov)
  • Experiments on bilayers and monolayers containing lipids such as dipalmitoylphosphatidylcholine (DPPC) provide the essential target data for this project. (nih.gov)
  • A unique surface interaction for perdeuterated ethanol and 1-butanol with dipalmitoylphosphatidylcholine (DPPC)/monosialoganglioside (G M1 ) multilamellar vesicles can be detected from the fast exchange averaging of the nuclear quadrupole coupling constant of the alcohol in the free and bound states using deuterium NMR. (elsevierpure.com)
  • Raman spectra of aqueous dispersions of 1,2-dipalmitoyl-phosphatidylcholine (DPPC) have been measured as a function of pressure (up to 46 kbar) for samples incubated at 2°C and for nonincubated DPPC samples subjected to equally high pressure. (canada.ca)
  • We have modelled a flat bilayer and a liposome composed of dipalmitoylphosphatidylcholine (DPPC), using molecular dynamics simulation. (bvsalud.org)
  • In this work, the formation of aqueous lipid/nanoparticle assemblies (LNAs) consisting of hydrophobic silver-decanethiol particles (5.7 ± 1.8 nm) embedded within 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers is demonstrated as a function of the DPPC/Ag nanoparticle (AgNP) ratio. (biomedcentral.com)
  • A phospholipid membrane, consisting of 1024 dipalmitoylphosphatidylcholine (DPPC) lipids in a bilayer configuration with 23 water molecules per lipid, for a total of 121,856 atoms. (rescale.com)
  • A quantitative comparison of 1,2-dipalmitoylphosphatidylcholine (DPPC) and 1,2-dipalmitoylphosphatidylethanolamine (DPPE) shows the former to have 0.4 double gauche (gg), 0.5 end gauche (eg), and about 1.0 (kink + gtg) conformers per chain just above the gel-liquid crystal phase transition, while the more highly ordered DPPE L α phase shows about 0.2 gg, 0.1 eg, and 1.0 (kink + gtg) conformers. (researchwithrutgers.com)
  • The intensity of the progression has been used to monitor the all-trans conformational state in phospholipid aqueous phases and in various regions of the 1,2-dipalmitoylphosphatidylcholine (DPPC)/cholesterol phase diagram. (researchwithrutgers.com)
  • Phase-separation was observed in the form of domains made of dipalmitoylphosphatidylcholine (DPPC), sphingomyelin (SM), or SM/cholesterol (SM/Chl) surrounded by a fluid matrix of dioleoylphosphatidylcholine (DOPC). (ac.be)
  • Dipalmitoylphosphatidylcholine (DPPC) is the main component of lung surfactants. (who.int)
  • 2] Alsop, R. J., Maria, Schober R., and Rheinstadter, M. C. Swelling of Phospholipid Membranes by Divalent Metal Ions Depends on the Location of the Ions in the Bilayers. (sciendo.com)
  • A Phospholipase A1 which is capable of hydrolyzing a phospholipid to produce a 2-acyl lysophospholipid and is obtainable from species of the fungus Aspergillus. (justia.com)
  • Selective hydrolysis of a phospholipid substrate with a Phospholipase A1 produces a 2-acyl lysophospholipid and selective hydrolysis of a phospholipid with a Phospholipase A2 results in the production of a 1-acyl lysophospholipid. (justia.com)
  • A series of CH 2 wagging modes in the 1320-1370-cm -1 region of alkane and phospholipid IR spectra characteristic of nonplanar conformers has been used for quantitative evaluation of conformational states in disordered (phospholipid L α and H II and alkane liquid) phases. (researchwithrutgers.com)
  • The second phospholipid may be 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)2000] (DSPE-mPEG2000) or 1,2-disteroyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000] (DSPE-PEG2000-MAL). (justia.com)
  • Lasonder, E & Weringa, WD 1990, ' An NMR and DSC study of the interaction of phospholipid vesicles with some anti-inflammatory agents ', Journal of Colloid and Interface Science , vol. 139, no. 2, pp. 469-478. (northumbria.ac.uk)
  • By employing coarse-grained molecular dynamics simulations, we obtained the temperature-pressure phase diagrams of a dipalmitoylphosphatidylcholine bilayer, which exhibits a gel phase and a fluid phase, with variation of the C 60 versus lipid ratios. (rsc.org)
  • A critical area per lipid of 0.594 ± 0.002 nm 2 is obtained when the ratio of C 60 reaches 6.4% while that of the pure bilayer case is 0.572 ± 0.002 nm 2 . (rsc.org)
  • The effect of substitution on their photochromic properties and relative orientation within the lipid bilayer of dipalmitoylphosphatidylcholine large unilamellar vesicles (LUVs) has been examined. (syr.edu)
  • During the last decades, the approach to overcome the complexity of biological membranes is to use simplified biomimetic models mainly consisting of binary or ternary mixtures of lipids [ 1 , 2 ]. (hindawi.com)
  • Interactions of vesicles of dipalmitoyl phosphatidylcholine with the anti-inflammatory agents sulindac sulfide, naproxen, phenylbutazone, and indomethacin and the structurally related physiologically inactive compounds sulindac, sulindac sulfone, and 5-methoxy-2-methyl-indole-3-acetic acid were studied by differential scanning calorimetry and by the measurement of nuclear Overhauser effects (NOEs), using 1D- and 2D-NMR methods. (northumbria.ac.uk)
  • Lamellar bodies in the TYPE 2 PNEUMOCYTES produce and secrete PULMONARY SURFACTANT (e.g. (bvsalud.org)
  • In an additional example, ibuprofen permeation through a dipalmitoylphosphatidylcholine membrane was modeled. (bvsalud.org)
  • Here, we employ the phase-sensitive membrane dye di-4-ANEPPDHQ together with a variety of spectrally-resolved microscopy techniques, including 2-channel ratiometric TIRF microscopy and fluorescence lifetime imaging, to characterize membrane order at the T cell immunological synapse at high spatial and temporal resolution in live cells at physiological temperature. (ox.ac.uk)
  • Uridine diphosphate-glucuronosyltransferases (UGTs) are phase 2 conjugation enzymes mainly located in the endoplasmic reticulum (ER) of the liver and many other tissues, and can be recovered in artificial ER membrane preparations (microsomes). (mdpi.com)
  • For example, Tutorial 2: Molecular Dynamics) To change the name of your project, click on the pencil (shown in blue, below) next to the current job name in the top left corner of the window. (rescale.com)
  • Sathyanarayana, N. Gummadi Transbilayer Movement of Dipalmitoylphosphatidylcholine in Proteoliposomes Reconstituted from Detergent Extracts of Endoplasmic Reticulum / N. Gummadi Sathyanarayana, Menon Anant K. // J. Biol. (surgery.by)
  • At 20 mol % cholesterol, a phase separation region is evident from 39 to 45°C. The conversion of the "liquid-ordered" to the "liquid-disordered" phase is accompanied by the formation of 0.15 double gauche conformers/chain, as monitored from localized CH 2 wagging vibrations. (researchwithrutgers.com)
  • The shapes of the domains were found to change dramatically when a small amount (2 mol %) of cholesterol was incorporated in the monolayer. (mun.ca)
  • Among the four surfactant apoproteins identified, surfactant protein B (SP-B) and SP-C are two small hydrophobic proteins that make up 2-4% of the surfactant mass and are present in commercially available surfactant preparations. (medscape.com)
  • Stud Univ Babes-Bolyai, Biol 24(2):32-35. (cdc.gov)
  • A Phospholipase A2 hydrolyzes the 2-acyl, or central acyl, group and Phospholipases C and D, which are also known as phosphodiesterases, cleave on the two sides of the phosphodiester linkage. (justia.com)
  • Substantially more disorder is observed (∼2-2.5 gauche rotamers/chain at 50°C). The various IR measurements of acyl chain conformational order are compared. (researchwithrutgers.com)
  • Thus, the species active on CD36 have been identified to have an sn-2 acyl group that incorporates a terminal g -hydroxy (or oxo)- a , b -unsaturated carbonyl (alcohol or aldehyde group). (gerli.com)
  • The compounds generated from different precursors are similar except for the chain length of the truncated oxidized fatty acid at the sn-2 position. (gerli.com)
  • The ratio of reorientational relaxation time for Legendre polynomials of order 1 and 2 is approximately 2 for interface, intermediate, and bulk water, indicating the presence of jump dynamics in these water molecules. (iisc.ac.in)
  • 1,2-diacyl-sn-glycero-3-phosphorylcholine or phosphatidylcholine or lecithin . (gerli.com)
  • 1993. In vitro percutaneous absorption and metabolism in man of 2-chloro-4-ethylamino-6-isopropylamine-s-triazine (atrazine). (cdc.gov)
  • In animal cells, the fatty acid from the 1-position is frequently 16:0 and that from the 2-position is 18:1 or 18:2, exceptionally more unsaturated fatty acids are found. (gerli.com)
  • Although acetoxy derivatives of the 3,13- and 2,13-dienes showed almost the same mass spectra, the alcohols were distinguished by comparing the relative intensities of [M−18] + at m ⁄ z 248, indicating direct differentiation of the two positional isomers without derivatization. (go.jp)
  • The SP-B gene is on human chromosome 2, and its primary translation product is 40 kd, which is clipped to become an 8-kd protein in the type II cells before entering lamellar bodies to be cosecreted with phospholipids. (medscape.com)
  • The main transition temperature, T m , remains almost unchanged with the addition of C 60 below a ratio of 4.7%, while a 2 K decrease of T m is observed at a ratio of 6.4% under various pressures. (rsc.org)
  • These two sites are thought to differ functionally with site 1 acting as the initial starch recognition site and site 2 involved in the specific recognition of appropriate regions of starch. (unl.edu)
  • The effect of MWCNTs surface charge was also investigated in terms of amino (−NH 2 ) and carboxyl (−COOH) surface modifications. (biomedcentral.com)
  • The Journal of Physical Chemistry B 5-2- 2015b;119(5):1947-56. (sciendo.com)
  • Journal of Rare Diseases Research & Treatment 7(2), pp. 1-4. (cardiff.ac.uk)
  • Journal of Photochemistry and Photobiology A: Chemistry , 189 (2-3), 224-231. (syr.edu)
  • Results 1-2 of 2 (Search time: 0.006 seconds). (edu.au)
  • The serial images obtained using TEM are aligned and stacked, at which point software is used to render a 3-dimensional representation of the imaged tissue ( Figure 2 and Figure 19 ). (chronopause.com)
  • Figure 4 Open in a unyoke window Mean reaction times as a succeedment in behalf of explore detection as a practicality of transition probability of characters in position 3 of verse word condition in Experiment 2. (upb.ro)
  • These structures were shown to derived from phosphatidylcholine molecules having C16:0 at the sn-1 position and either C18:2n-6, C20:4n-6 or C22:6n-3 at the sn-2 position. (gerli.com)
  • MNPs are tiny needles, small enough (100 -1,000 μm) that perforate superficial layers of the skin to deliver therapeutic agent into the dermis in a relatively painless and invasive manner [1, 2]. (pulsusconference.com)
  • This work naturally follows from 1 and 2, and, ultimately, will become the primary focus of the section. (nih.gov)
  • Based on their structure CNTs are classified as either, single-wall carbon nanotubes (SWCNTs), which comprise a single layer of carbon atoms, or multi-wall carbon nanotubes (MWCNTs), comprising of multiple concentric tubes [ 2 ]. (biomedcentral.com)