• Transcription factor 7-like 2 ( TCF7L2 ) variants have been associated with type 2 diabetes mellitus (T2DM) in multiple ethnic groups. (medscape.com)
  • There was no significant difference in allele and genotype frequencies of +276G>T between type T2DM patients and controls. (who.int)
  • Type 2 diabetes mellitus (T2DM) is one of the common metabolic diseases in the world. (frontiersin.org)
  • Type 2 diabetes mellitus (T2DM) is a progressive metabolic disease characterized by pancreatic β-cell dysfunction and peripheral insulin resistance, leading to defects in glucose metabolism and chronic low-grade inflammation. (frontiersin.org)
  • The global prevalence of Type 2 Diabetes Mellitus (T2DM) has been on the rise over the last four decades and is expected to rise further. (easychair.org)
  • August 1, 2014 - The FDA has approved Jardiance (empagliflozin) tablets in conjunction with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus (T2DM). (pharmacytimes.com)
  • To assess the efficacy and safety of berberine in the treatment of type 2 diabetes mellitus (T2DM). (hindawi.com)
  • Type 2 diabetes mellitus (T2DM) is the most common form of diabetes. (hindawi.com)
  • Initial therapy for treating T2DM includes diet and exercise, followed by the use of oral hypoglycemic agents and potentially subcutaneous insulin injections [ 1 , 2 ]. (hindawi.com)
  • Type 2 diabetes mellitus (T2DM)-related cognitive decline is associated with neuroimaging changes. (frontiersin.org)
  • Type 2 diabetes mellitus (T2DM) is a systemic metabolic disease, resulting in severe complications of multiple systems. (frontiersin.org)
  • Eighty-two adult subjects with diagnosed T2DM were recruited from the Diabetes Mellitus Outpatient Clinic of the 3rd Department of Internal Medicine, situated at Papageorgiou General Hospital, Thessaloniki, Greece, and divided into two groups according to the presence or absence of DPN. (springer.com)
  • Objective: In China, a low-fat diet (LFD) is mainly recommended to help improve blood glucose levels in patients with type 2 diabetes mellitus (T2DM). (mdpi.com)
  • This study investigated differences in suicide and all-cause mortality from ICD-9-CM comorbid major depressive disorder (MDD) and type 2 diabetes mellitus (T2DM) depending on which was diagnosed first. (psychiatrist.com)
  • Patients with newly diagnosed T2DM were identified and further classified into 3 groups: (1) MDD before T2DM, (2) T2DM without any diagnosis of MDD (from which matched controls were selected), and (3) MDD after T2DM, based on the sequential occurrence dates between incident T2DM and MDD. (psychiatrist.com)
  • Individuals with severe mental illness or type 2 diabetes mellitus (T2DM) have increased levels of peripheral immune-inflammatory biomarkers, which may contribute to neurocognitive and social deficits, according to a study recently published in the Frontiers of Neurology . (medicalxpress.com)
  • We analyzed the association between adherence of a MeDiet in patients with type 2 diabetes mellitus (T2DM) and levels of HbA1c. (nuthealth.org)
  • The aim of this study was therefore to evaluate the plasma levels of FABP3 at different stages of estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes mellitus (T2DM). (medsci.org)
  • Background: In China, traditional Chinese medicine (TCM) has been used to treat type 2 diabetes mellitus (T2DM) for centuries. (benthamscience.com)
  • Introduction Type 2 diabetes mellitus (T2DM) is a highly prevalent chronic disease in the Spanish population. (bmj.com)
  • Background: The complex disease of diabetes mellitus type 2 (T2DM) requires a high standard of quality of care. (eur.nl)
  • Clinical practice guidelines define norms for diabetes care that ensure regular monitoring of T2DM patients, including annual diagnostic tests. (eur.nl)
  • As the burden of disease from diabetes rises to epidemic proportions, RGA's Heather Lund asks in On the Risk whether the possibility of remission for Type 2 diabetes mellitus (T2DM) signals an opportunity to escape a major public health traffic jam. (rgare.com)
  • But in recent years, despite initial scanty evidence, there is mounting data that suggests some reversibility in established Type 2 diabetes mellitus (T2DM), particularly in those with short duration. (rgare.com)
  • Despite earlier evidence suggesting remission is possible, it is only as recent as 2016 that reference to T2DM reversal was added to the World Health Organization (WHO) Global Report on Diabetes. (rgare.com)
  • BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is a chronic disease that affects millions of people, and according to the International Diabetes Federation, 46.5% of people have undiagnosed diabetes. (galileo-training.com)
  • The reported prevalence of low testosterone among men with type 2 diabetes mellitus (T2DM) is high. (samj.org.za)
  • In a cross-sectional observational study, androgen deficiency symptoms in men with T2DM attending two outpatient diabetes clinics in Durban, KwaZulu-Natal Province, SA, were assessed using the Ageing Males' Symptoms Scale (AMS) questionnaire and direct enquiry. (samj.org.za)
  • Objective: To determine whether inflammatory macrophages contribute to neuropathic pain associated with type 2 diabetes-mellitus (T2DM). (atsbio.com)
  • We investigated the association between alterations in regular physical activity (PA) and the risk of developing AF in patients with type 2 diabetes mellitus (T2DM) and the optimal PA range based on energy expenditure. (diabetesjournals.org)
  • Type 2 diabetes mellitus (T2DM) is a chronic disease that can cause adverse effects if not managed effectively. (researchprotocols.org)
  • The prevalence of T2DM will continue to rise every year, and data from the International Diabetes Federation show that the number of patients diagnosed with T2DM in Indonesia is predicted to increase from 10.3 million in 2017 to 16.7 million in 2045. (researchprotocols.org)
  • Type 2 diabetes mellitus (T2DM) is a frequent co-morbidity, and a negative prognostic risk factor in patients with heart failure and reduced left ventricle ejection fraction (HFrEF), [ 1 ]. (biomedcentral.com)
  • Most pediatric patients with type 2 diabetes belong to minority communities. (medscape.com)
  • One of the first steps in the management of patients with type 2 diabetes mellitus is setting glycemic goals. (nih.gov)
  • Jardiance provides an additional treatment option for the care of patients with type 2 diabetes,' said Curtis J. Rosebraugh, MD, MPH, director of the Office of Drug Evaluation II in the FDA's Center for Drug Evaluation and Research. (pharmacytimes.com)
  • There is dearth of data on the prevalence of latent tuberculosis infection among patients with type 2 diabetes. (ersjournals.com)
  • Metformin is widely accepted as first-line pharmacotherapy for patients with type 2 diabetes mellitus when glycemic control cannot be achieved by lifestyle interventions alone. (cmaj.ca)
  • For most patients with type 2 diabetes that is inadequately controlled with metformin monotherapy, the addition of a sulphonylurea represents the most cost-effective second-line therapy. (cmaj.ca)
  • 8 As part of a larger initiative to determine optimal prescribing of antihyperglycemic agents, we sought to determine the incremental cost-effectiveness of treatment with alternative second-line agents added to metformin in patients with type 2 diabetes no longer adequately controlled by metformin monotherapy. (cmaj.ca)
  • As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in patients with type 2 diabetes mellitus and no history of cardiovascular events. (springer.com)
  • Mortality of patients with type 2 diabetes in Taiwan: a 10-year nationwide follow-up study. (psychiatrist.com)
  • Major depressive disorder in patients with type 2 diabetes mellitus: prevalence and clinical characteristics. (psychiatrist.com)
  • Marta Garés-Caballer et al, Immune-Inflammatory Biomarkers Predict Cognition and Social Functioning in Patients With Type 2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: A 1-Year Follow-Up Study, Frontiers in Neurology (2022). (medicalxpress.com)
  • Methods: We conducted a prospective case-control study in which we inclu ded 200 subjects divided into 100 patients with type 2 diabetes and 100 controls in apparent good health. (scirp.org)
  • Adherence to the mediterranean diet in patients with type 2 diabetes mellitus and HbA1c Level. (nuthealth.org)
  • What is recommended for optimal glycemic control in patients with type 2 diabetes at diagnosis and obviously as they progress? (medicaleconomics.com)
  • Acute Effects of a Whole Body Vibration Session on the Vibration Perception Threshold in Patients with Type 2 Diabetes Mellitus. (galileo-training.com)
  • As previously stated, patients with type 2 diabetes mellitus can usually be differentiated from those with type 1 disease on the basis of history and physical examination findings and through simple laboratory tests. (medscape.com)
  • Patients with type 2 diabetes are generally obese, and may have acanthosis nigricans and/or hirsutism in conjunction with thick necks and chubby cheeks. (medscape.com)
  • Nutrients and Dietary Approaches in Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease: A Narrative Review. (scienceplay.com)
  • The guidelines recommend insulin treatment in all patients who present with ketosis or extremely high blood glucose levels because it may not be clear initially whether these patients have type 2 or type 1 diabetes. (medscape.com)
  • Type 2 diabetes occurs when your body's cells resist the normal effect of insulin, which is to drive glucose in the blood into the inside of the cells. (harvard.edu)
  • The symptoms of diabetes are related to high blood glucose levels. (harvard.edu)
  • Diabetes describes a group of metabolic diseases in which the person has high blood glucose because insulin production is inadequate, or because the body 's cells do not respond properly to insulin, or both. (bartleby.com)
  • However, over time your pancreas is not able to keep up and can not make enough insulin to keep your blood glucose at normal levels(www.diabetes.org). (bartleby.com)
  • The individualization of HbA(1c) targets has gained more traction after recent clinical trials in older patients with established type 2 diabetes mellitus failed to show a benefit from intensive glucose-lowering therapy on cardiovascular disease (CVD) outcomes. (nih.gov)
  • The use of Jardiance--a sodium glucose co-transporter 2 inhibitor--blocks the reabsorption of glucose by the kidneys, increasing glucose excretion and lowering the blood glucose level in patients with diabetes who have an elevated blood glucose level. (pharmacytimes.com)
  • Because combination treatment has been shown to be superior to metformin alone for decreasing A1C levels, weight, and blood pressure, adding a sulfonylurea, thiazolidinedione, or sodium glucose cotransporter-2 (SGLT-2) or dipeptidyl peptidase-4 (DPP-4) inhibitor can be considered when additional oral treatment is being discussed. (aafp.org)
  • Metformin monotherapy is widely recommended as first-line pharmacotherapy, 1 , 2 given its favourable effects in controlling blood glucose and body weight, low risk of hypoglycemia, low cost and association with mortality benefit. (cmaj.ca)
  • To accomplish ideal glucose control, complex treatment anticipates individuals with type-2 diabetes may include day by day blood glucose testing and checking, fittingly endorsed solutions, for example, oral hypoglycemic agents and/or insulin infusion, nutrition treatment and standard exercise 3 - 5 . (scialert.net)
  • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. (bmj.com)
  • QUESTION: In patients with impaired glucose tolerance, is a lifestyle intervention programme effective for preventing type 2 diabetes mellitus? (bmj.com)
  • Pre-diabetes (impaired glucose regulation) is known to be reversible. (rgare.com)
  • Prediabetes is defined by a fasting blood glucose level of 100-125 mg/dL or a 2-hour post-oral glucose tolerance test (post-OGTT) glucose level of 140-200 mg/dL. (medscape.com)
  • Metabolic syndrome, thought to be due to insulin resistance, can occur in patients with overtly normal glucose tolerance, prediabetes, or diabetes. (medscape.com)
  • Prevention of hypoglycaemia is an important part of diabetes mellitus management and strategies include patient education, glucose monitoring, appropriate adjustment of diet and medications in relation to everyday circumstances including physical exercise, and the application of new technologies such as real-time continuous glucose monitoring, modified insulin pumps and the artificial pancreas. (nature.com)
  • The term diabetes includes several different metabolic disorders that all, if left untreated, result in abnormally high concentrations of a sugar called glucose in the blood. (wikipedia.org)
  • The treatment goals are related to effective control of blood glucose, blood pressure and lipids, to minimize the risk of long-term consequences associated with diabetes. (wikipedia.org)
  • Quality of measurement properties of medication adherence instruments in cardiovascular diseases and type 2 diabetes mellitus: a systematic review and meta-analysis. (bvsalud.org)
  • We used the United Kingdom Prospective Diabetes Study Outcomes Model to forecast diabetes-related complications, quality-adjusted life-years and costs of alternative second-line therapies available in Canada for adults with type 2 diabetes inadequately controlled by metformin. (cmaj.ca)
  • We used the United Kingdom Prospective Diabetes Study Outcomes Model 9 to conduct an incremental cost-utility analysis comparing alternative second-line therapies for adults with type 2 diabetes inadequately controlled by metformin. (cmaj.ca)
  • The objective of the study was to explore the views and experiences of adults with type 2 diabetes mellitus on a nutrition education programme. (ajol.info)
  • The study subjects were adults with type 2 diabetes mellitus ( n = 41, aged 40-70 years) participating in a nutrition education intervention (one-year randomised controlled trial). (ajol.info)
  • The aim is to assess adherence to anti diabetic drug therapy and self management practice among type-2 diabetic patient in Ethiopia. (nih.gov)
  • A cross-sectional review of randomly selected 384 case notes of type-2 diabetic patient that attend diabetes mellitus clinic over 3 month and cross-sectional interview, with pre tested adherence and self management and monitoring tool questioner of 347 consecutive patients that attend in Jimma university specialized hospital diabetic clinic. (nih.gov)
  • Guideline adherence was measured by comparing structure and process indicators of care with recommendations in the national diabetes care guideline. (eur.nl)
  • Conclusions: Guideline adherence in Dutch general practices offering diabetes care was not optimal. (eur.nl)
  • Medication adherence has a major impact on reducing mortality and healthcare costs related to the treatment of cardiovascular diseases and diabetes mellitus . (bvsalud.org)
  • This study aims to critically assess, compare and synthesize the quality of the measurement properties of patient-reported outcome measures to assess medication adherence among patients with cardiovascular diseases and/or type 2 diabetes mellitus . (bvsalud.org)
  • Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. (medscape.com)
  • 2 WHO, WHO/IDF report of consultation: Definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia , Geneva, World Health Organization, 2006. (who.int)
  • Evidence abound that the most important predictor of reduction of morbidity and mortality due to diabetes complication is the level of glycemic control achieved. (nih.gov)
  • Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and has been associated with cardiovascular disease, the leading cause of mortality in diabetes. (springer.com)
  • Depression and mortality in type 2 diabetes mellitus. (psychiatrist.com)
  • Diabetes constitutes one of the major independent cardiovascular risk factors, and patients with this disease suffer from premature cardiovascular morbidity and mortality. (scirp.org)
  • Patients with CKD are at a high risk of cardiovascular disease and mortality and are associated with increased treatment costs [ 2 ]. (medsci.org)
  • Diabetes causes significant morbidity and premature mortality. (rgare.com)
  • Physical inactivity increases all causes of mortality, doubles the risks of cardiovascular diseases, type 2 Diabetes and obesity. (who.int)
  • Diagnosis, classification, and pathogenesis of diabetes mellitus. (jabfm.org)
  • Insulin supersensitivity and normoinsulinaemic hypoglycaemia might play a role in clinical manifestation and pathogenesis of type 2 DM. (bmj.com)
  • International Diabetes Federation (IDF) estimates the global prevalence of diabetes to be 425 million. (easychair.org)
  • According to the latest figures from the International Diabetes Federation (IDF), the number of individuals with diabetes in 2011 has reached a staggering 366 million, causing 4.6 million deaths each year. (hindawi.com)
  • The World Health Organization and the International Diabetes Federation (IDF) jointly carried out other actions to contribute to it. (who.int)
  • Methods and analysis A multicentre quasi-experimental design comparing a group of individuals taking part in the intervention (intervention group (IG)) with a similar group receiving standard diabetes care (comparison group (CG)) is planned. (bmj.com)
  • Material and research methods: We for the period from January, 01.2017 to December, 31, 2017 year 102 patients with type 1 and type 2 diabetes mellitus were examined. (endocrine-abstracts.org)
  • Materials and Methods: The study was done as a cross‑sectional study in a tertiary care medical college hospital for 2 years among 218 adults patients of both sexes with type 2 diabetes mellitus. (who.int)
  • The treatment of type 2 diabetes also can produce symptoms. (harvard.edu)
  • The use of the term diabetes "remission" is preferred, as it best reflects the improved symptoms and biochemical status. (rgare.com)
  • A 60-year-old man with uncontrolled type 2 diabetes mellitus (DM) (glycated haemoglobin 11%) had the unusual symptoms of palpitations and sweating after drinking an excessive amount of soft drinks. (bmj.com)
  • The association of NAFLD in type 2 diabetes mellitus patients with symptoms of angina according to modified rose and ECG changes using Minnesota codes was studied. (who.int)
  • The person living with diabetes can experience symptoms from such comorbidities which may impact function, emotional well-being, and quality of life as well as morbidity from complications that may limit work productivity, increase absenteeism, and lead to premature loss of employment. (cdc.gov)
  • Famines in the Last 100 Years: Implications for Diabetes. (medigraphic.com)
  • Increased use of newer, more costly agents, along with the rising incidence of type 2 diabetes, carries significant budgetary implications for health care systems. (cmaj.ca)
  • The review summarised the techniques that have proven to be effective for the Published: 29 May 2023 self-management of type 2 diabetes. (who.int)
  • Only 5% of people with diabetes have this form of the disease. (bartleby.com)
  • It is a burden on health care systems and costly to treat - with international figures showing medical costs for people with diabetes are two-to-threefold greater, when compared with those without diabetes. (rgare.com)
  • Participants also recommended the programme to other people with diabetes mellitus. (ajol.info)
  • Whereas coma and seizures are well-recognized neurological sequelae of hypoglycaemia, much interest is currently focused on the potential for hypoglycaemia to cause dangerous and life-threatening cardiac complications, such as arrhythmias and myocardial ischaemia, and whether recurrent severe hypoglycaemia can cause permanent cognitive impairment or promote cognitive decline and accelerate the onset of dementia in middle-aged and elderly people with diabetes mellitus. (nature.com)
  • Received: 14 Nov. 2022 improving self-management of type 2 diabetes, especially in a South African context. (who.int)
  • Type 2 diabetic patients attending medical outpatient clinic in a Specialist Hospital in Nigeria and apparently healthy controls matched for age and sex were recruited.Socio demographic and clinical data were obtained through a pro forma. (ersjournals.com)
  • The limited available evidence suggests that near-normal glycemic targets should be the standard for younger patients with relatively recent onset of type 2 diabetes mellitus and little or no micro- or macrovascular complications, with the aim of preventing complications over the many years of life. (nih.gov)
  • We're now in a different world where we have diabetes drugs that can lower macrovascular disease. (medicaleconomics.com)
  • Persons with prediabetes are at increased risk for macrovascular disease, as well as diabetes. (medscape.com)
  • Once a diagnosis of type 2 diabetes is confirmed, lifestyle modification and metformin treatment should be initiated. (medscape.com)
  • GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 diabetes (T2D). (lu.se)
  • The prevalence of diabetes is currently estimated to be about 6.4% worldwide, 1 and in the past two decades alone there has been a dramatic increase in the diagnosis of type 2 diabetes. (bmj.com)
  • For correspondence: Professor J Tuomilehto, National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Mannerheimintie 166, FIN-00300 Helsinki, Finland. (bmj.com)
  • We conducted this analysis to determine the relative costs, benefits and cost-effectiveness of options for second-line treatment of type 2 diabetes. (cmaj.ca)
  • In contrast, treatment of type 2 diabetes consists of lifestyle measures and a variety of other medications, with insulin introduced if those prove inadequate. (medscape.com)
  • Type-2 diabetes mellitus and its complication are becoming more prevalent in Ethiopia. (nih.gov)
  • Diabetic peripheral neuropathy (DPN) is the most prevalent neuropathy in diabetes and a common cause of morbidity. (springer.com)
  • If glycemic control needs to be improved with medication in persons with type 2 diabetes, metformin should be prescribed because it can efficiently lower glycemic levels, is linked to losing weight and fewer occurrences of hypoglycemia, and is generally less expensive than other options. (aafp.org)
  • These therapies provide reasonable durable glycemic control but are unable to arrest the natural progression of diabetes or the eventual need for insulin. (bvsalud.org)
  • Exposures were demographic, socioeconomic, health behavior, and clinical risk factors before the onset of type 2 DM. (ajmc.com)
  • Topics in the Prevention, Treatment and Complications of Type 2 D. (intechopen.com)
  • Obesity greatly increases the risk of diabetes. (harvard.edu)
  • However, somewhat higher targets should be considered for older patients with long-standing type 2 diabetes mellitus and evidence of CVD (or multiple CVD risk factors). (nih.gov)
  • Summary estimates showed that greater intake of green leafy vegetables was associated with a 14% (hazard ratio 0.86, 95% confidence interval 0.77 to 0.97) reduction in risk of type 2 diabetes (P=0.01). (bmj.com)
  • Conclusion Increasing daily intake of green leafy vegetables could significantly reduce the risk of type 2 diabetes and should be investigated further. (bmj.com)
  • 12 13 Diabetes is a strong independent risk factor for cardiovascular disease, 14 and often the conditions exist together, sharing common modifiable risk factors. (bmj.com)
  • 15 As yet no firm conclusions have been made as to whether increasing intake of fruit and vegetables can decrease the risk of type 2 diabetes itself, given the abundance of conflicting evidence within the literature. (bmj.com)
  • Diabetes risk factors are well known. (scirp.org)
  • These outbreaks prompted the Hepatitis Vaccines Work Group of the Advisory Committee on Immunization Practices (ACIP) to evaluate the risk for HBV infection among all adults with diagnosed diabetes. (cdc.gov)
  • Based on the Work Group findings, on October 25, 2011, ACIP recommended that all previously unvaccinated adults aged 19 through 59 years with diabetes mellitus (type 1 and type 2) be vaccinated against hepatitis B as soon as possible after a diagnosis of diabetes is made (recommendation category A). Data on the risk for hepatitis B among adults aged ≥60 years are less robust. (cdc.gov)
  • Therefore, ACIP recommended that unvaccinated adults aged ≥60 years with diabetes may be vaccinated at the discretion of the treating clinician after assessing their risk and the likelihood of an adequate immune response to vaccination (recommendation category B). This report summarizes these recommendations and provides the rationale used by ACIP to inform their decision making. (cdc.gov)
  • The population risk for HBV infection among adults with diagnosed diabetes was estimated from 865 confirmed cases of acute HBV infection reported during 2009-2010 from eight Emerging Infections Program (EIP) sites constituting approximately 17% of the U.S. population. (cdc.gov)
  • Compounds in cocoa and chocolate have established cardiovascular benefits, including beneficial effects on insulin resistance, a risk factor for type 2 diabetes mellitus. (umaine.edu)
  • Type 2 diabetes is a chronic non-transmissible disease, acquired and modifiable with lifestyle factors, despite having an important genetic risk factor. (scienceplay.com)
  • Strong evidence shows that unhealthy diet and insufficient physical activity are among the major causal risk factors in coronary heart disease, cerebrovascular strokes, several forms of cancer, type 2 diabetes, hypertension, obesity, osteoporosis, dental caries, and other conditions. (who.int)
  • Physical activity is essential for preventing and controlling risk factors and chronic diseases, such as diabetes, high blood pressure (HBP), cardiovascular disease (CVD), obesity, cancer, and depression (1). (cdc.gov)
  • Some studies indicate that proximity to green spaces is linked to a lower risk of HBP, improved diabetes outcomes, and reduced obesity (4-8). (cdc.gov)
  • Novel biomarkers of risk, such as apolipoprotein (Apo) A1 and ApoB (2), and the inflammatory markers C-reactive protein (CRP), fibrinogen, and homocysteine (3-5), have been proposed. (cdc.gov)
  • While aging and exposure to loud noise and other ototoxic substances are well-known risk factors for hearing loss, research conducted over the past several decades has brought attention to sensorineural hearing loss among individuals with other health problems such as diabetes. (cdc.gov)
  • For those born in 2000, the estimated lifetime risk for developing diabetes is 32.8% for males and 38.5% for females, and the risk is even higher in certain minority groups. (cdc.gov)
  • Risk factors for type 2 diabetes are complex and include genetic predisposition, lifestyle issues such as insufficient exercise, diet and smoking, as well as environmental components. (cdc.gov)
  • This chapter gives a brief overview of the evidence for prevention of Type 2 Diabetes (behavioural and pharmacological) and describes various approaches to screening, from an international perspective, together with their relative advantages and disadvantages. (intechopen.com)
  • for the Finnish Diabetes Prevention Study Group. (bmj.com)
  • Randomised (allocation concealed * ), unblinded, * controlled trial with mean follow up of 3.2 years (the Finnish Diabetes Prevention Study). (bmj.com)
  • The present strategy urges Member States to evaluate the magnitude of diabetes and identify and improve areas of intervention in terms of primary, secondary and tertiary prevention activities. (who.int)
  • This document examines the situation of diabetes (Type 2) in the African Region and proposes a strategy for its prevention and control. (who.int)
  • This trend is a serious threat to public health, as diabetes is associated with severe and potentially fatal complications and comorbidities, such as cardiovascular disease, kidney disease, visual impairment, neuropathies, and infectious complications. (cdc.gov)
  • The incidence of non insulin dependent diabetes is 3-7 times greater in over weight as compared to average weight adults , amendment in lifestyle also denoted as behavioral weight control includes three basic factors: diet, exercise and behavior therapy. (bartleby.com)
  • Type 1 diabetes can be managed by using insulin therapy and other treatments to help those infected maintain insulin to convert sugars, starches and foods into energy(www.diabetes.org). (bartleby.com)
  • However, uncertainty exists regarding the optimal second-line therapy for patients whose diabetes is inadequately controlled by metformin monotherapy. (cmaj.ca)
  • 4 In light of current therapeutic uncertainty, the large proportion of patients requiring second-line therapy over time 3 , 6 and the increasing prevalence of type 2 diabetes, 7 the utilization and cost of second-line therapy are likely to continue to grow. (cmaj.ca)
  • The American Diabetes Association (ADA) thresholds (last updated in 2009) for pre-diabetes and diabetes are used, respectively, for partial and complete remission in the absence of active anti-diabetic therapy. (rgare.com)
  • To evaluate clinical outcomes in patients with diabetes, treated by cardiac resynchronization therapy with a defibrillator (CRT-d), and glucagon-like peptide 1 receptor agonists (GLP-1 RA) in addition to conventional hypoglycemic therapy vs. CRTd patients under conventional hypoglycemic drugs. (biomedcentral.com)
  • We investigated the 12-months prognosis of CRTd patients with diabetes, previously treated with hypoglycemic drugs therapy (n 271) vs. a matched cohort of CRTd patients with diabetes treated with GLP-1 RA in addition to conventional hypoglycemic therapy (n 288). (biomedcentral.com)
  • GLP-1 RA drugs in addition to conventional hypoglycemic therapy may significantly reduce systemic inflammation and circulating BNP levels in CRTd patients with diabetes, leading to a significant improvement of LVEF and of the 6 min walking test, and to a reduction of the arrhythmic burden. (biomedcentral.com)
  • Type 1 diabetes is an autoimmune destruction of pancreatic B-cells and subsequent dependence upon insulin therapy. (cdc.gov)
  • Objective To investigate the independent effects of intake of fruit and vegetables on incidence of type 2 diabetes. (bmj.com)
  • Study selection Prospective cohort studies with an independent measure of intake of fruit, vegetables, or fruit and vegetables and data on incidence of type 2 diabetes. (bmj.com)
  • There has been a focus on the role of carbohydrates and fibre, 2 3 but the relation between fruit and vegetable intake and incidence of type 2 diabetes is not fully understood. (bmj.com)
  • Because type 2 diabetes in children and adolescents is strongly associated with obesity and sedentary lifestyle, any intervention designed to increase physical activity and improve dietary habits should be encouraged. (medscape.com)
  • The hazards of overweight and obesity to the health of individuals and populations were demonstrated in a recent WHO report.1 Besides changes in body weight, diet and physical activity are linked to noncommunicable diseases through other mechanisms such as links between type of fat and low-density lipoprotein cholesterol, and between salt intake and blood pressure, often in people whose body weight is within normal range. (who.int)
  • Finding epigenetic evidence of the relationship between maternal malnutrici n and the development of type two diabetes mellitus is achieved not only decrease the incidence rate of the disease, preventing maternal malnutrition, but also progress in treatment studies towards of the problem target as for epigenetics it is discussed. (medigraphic.com)
  • Liraglutide, a glucagonlike peptide-1 (GLP-1) agonist, is the first noninsulin drug approved to treat type 2 diabetes in pediatric patients since metformin was approved for pediatric use in 2000. (medscape.com)
  • Metformin should be the first medication prescribed for diabetes when an oral agent is required. (aafp.org)
  • Type 2 diabetes mellitus, which occurs in up to 95% of persons with diabetes, is typically managed with lifestyle modifications (e.g., diet, exercise) and medication (e.g., oral drugs). (aafp.org)
  • For this reason, the ACP has released updated guidelines for the management of type 2 diabetes with oral medication. (aafp.org)
  • The Dietary Supplement and Prescription Medication section of the Sample Person (SP) Questionnaire collects information on: 1) dietary supplements, 2) nonprescription antacids, 3) prescription medications, and 4) preventive aspirin use. (cdc.gov)
  • Type 2 Diabetes Mellitus (DM2) is associated to cognitive and functional deficits and, one of the tools, which can be used to assess executive functions, is the WCST. (bvsalud.org)
  • The cause of type 2 diabetes is directly related to overweight, sedentary lifestyle, elevated triglycerides, hypertension, altered lipid profile, polycystic ovary syndrome, and inadequate eating habits. (scienceplay.com)
  • The early life origin theory in the development of cardiovascular disease and type 2 diabetes. (medigraphic.com)
  • Simplified scheme for the pathophysiology of type 2 diabetes mellitus. (medscape.com)
  • To improve our understanding of the aetiological factors and molecular processes driving the occurrence of GDM, including the extent to which these overlap with T2D pathophysiology, the GENetics of Diabetes In Pregnancy (GenDIP) Consortium assembled genome-wide association studies (GWAS) of diverse ancestry in a total of 5485 women with GDM and 347 856 without GDM. (lu.se)
  • Individuals were diagnosed for T2D according to the criteria given by the American Diabetes Association (ADA) 2011. (scirp.org)
  • Individuals with type-2 diabetes work proactively to optimize their conditions and well being as well as to reduce complications by using herbs and supplements which are known as complementary and alternative medicine (CAM) treatments 8 . (scialert.net)
  • However, individuals diagnosed with diabetes prior to the nutritional assessment consumed lower amounts of chocolate at the time of the dietary assessment. (umaine.edu)
  • individuals with type 2 diabetes. (who.int)
  • Self-management is the foundation of diabetes management because individuals actively to r t ead online. (who.int)
  • Its fundamental importance in energy balance and weight control and in reducing the risks of coronary heart disease, stroke, hypertension, diabetes, colon cancer, breast cancer, and depression has been widely recognized. (who.int)
  • Studies have identified the existence of a connection between Diabetes Mellitus and (DM) and dementia. (bvsalud.org)