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  • type 2 diabet
  • Men and women with type 2 diabetes have three- and fivefold higher cardiovascular mortality, respectively, than the nondiabetic population ( 2 ). (diabetesjournals.org)
  • The Nurses Health Study ( 3 ) showed an inverse association between nut consumption and the risk of type 2 diabetes. (diabetesjournals.org)
  • Despite the prevalence of endothelial dysfunction in diabetes and evidence that walnut consumption may improve both endothelial function and biomarkers of cardiovascular disease risk in patients with hypercholesterolemia, no studies have investigated the effect of walnut intake on endothelial function in type 2 diabetes. (diabetesjournals.org)
  • Twenty-four participants with type 2 diabetes were recruited from the Lower Naugatuck Valley in Connecticut through flyers and newspaper advertisements. (diabetesjournals.org)
  • The T2D Knowledge Portal enables browsing, searching, and analysis of human genetic information linked to type 2 diabetes and related traits, while protecting the integrity and confidentiality of the underlying data. (type2diabetesgenetics.org)
  • Please use the following citation when referring to data accessed via this portal: Type 2 Diabetes Knowledge Portal. (type2diabetesgenetics.org)
  • carrier rocket
  • Pegasus 2 was a Pegasus spacecraft, consisting of 1,450 kilograms (3,200 lb) of instruments, attached to the S-IV upper stage of the carrier rocket which had placed it into orbit. (wikipedia.org)
  • Pegasus 2 was a secondary payload on the carrier rocket, which was carrying a boilerplate Apollo spacecraft, Apollo 104 or BP-26, as part of a series of configuration tests for the Apollo program. (wikipedia.org)
  • gene
  • We identified a HIF-2-dependent gene signature in sensitive tumours. (nih.gov)
  • Sensitive tumours exhibited a distinguishing gene expression signature and generally higher levels of HIF-2α. (nih.gov)
  • resistance
  • Resistance occurred despite HIF-2 dissociation in tumours and evidence of Hif-2 inhibition in the mouse, as determined by suppression of circulating erythropoietin, a HIF-2 target and possible pharmacodynamic marker. (nih.gov)
  • Although emerging resistance mechanisms are being identified and resistant infections are on the rise, new antibiotic development has slowed considerably ( 2 ). (cdc.gov)
  • Molecular
  • As a result, 2-aminophenol has a rather high melting point compared to other compounds with a similar molecular mass such as methylphenol. (wikipedia.org)
  • resistant
  • Antibiotic-resistant infections contribute to poor health outcomes, higher health care costs, and use of more toxic treatments ( 2 ). (cdc.gov)
  • treatment
  • Both mutations preserved HIF-2 dimers despite treatment with PT2399. (nih.gov)
  • 1 - 4 The term "hemangioma" is, for example, commonly used to name different types of vascular tumors as well as vascular malformations, despite the different constitution, natural evolution, and treatment of these 2 groups of lesions. (aappublications.org)
  • 2-Phenylphenol (ortho-phenylphenol, OPP), and sodium o-phenylphenate, SOPP, were first evaluated by the 1962 JECFA for their use for the post-harvest treatment of fruits and vegetables to protect against microbial damage during storage and distribution in commerce. (wikipedia.org)
  • potential
  • The therapeutic potential of HIF-2 antagonism in renal cell carcinoma. (nih.gov)
  • CONCLUSIONS A walnut-enriched ad libitum diet improves endothelium-dependent vasodilatation in type 2 diabetic individuals, suggesting a potential reduction in overall cardiac risk. (diabetesjournals.org)
  • written
  • By the new millennium 100 million Seroxat prescriptions have been written worldwide bringing in 2 billion dollars a year. (bbc.co.uk)
  • For integers written in a numeral system based on an even number, such as decimal, hexadecimal, or in any other base that is even, divisibility by 2 is easily tested by merely looking at the last digit. (wikipedia.org)
  • Sonnet 2 is one of 154 sonnets written by the English playwright and poet William Shakespeare. (wikipedia.org)
  • Millennium 2 is a song written by Jan Nordlund, John Henrik Lagerlöf, Stefan Enberg and Daniel Bäckström, and recorded by Markoolio on his 1999 album Dikter från ett hjärta. (wikipedia.org)
  • style
  • In an even more barebones style than Covers 2, the songs are recorded simply, and feature no extras, effects or overdubs. (wikipedia.org)
  • song
  • AllMusic writes that "2 + 2" is "a frightening, visceral song that stands among the best anti-Vietnam protests. (wikipedia.org)
  • given
  • This is the mechanism by which the 2-opt swap manipulates a given route: 2optSwap(route, i, k) { 1. (wikipedia.org)
  • primary
  • The primary instrument aboard FalconSAT-2 was the Miniaturized Electrostatic Analyzer, or MESA. (wikipedia.org)
  • The primary use of 2-phenylphenol is as an agricultural fungicide. (wikipedia.org)
  • found
  • The theme of necessary procreation found in Sonnet 1 continues into Sonnet 2. (wikipedia.org)
  • Sonnet 2 is also a working of the standard 'siege' conceit found in many sonnets. (wikipedia.org)
  • 2-Phenylphenol is found in low concentrations in some household products such as spray disinfectants and aerosol or spray underarm deodorants. (wikipedia.org)
  • important
  • The number 2 is important in Judaism, with one of the earliest references being that God ordered Noah to put two of every unclean animal (Gen. 7:2) in his ark (see Noah's Ark). (wikipedia.org)
  • back
  • The glyph used in the modern Western world to represent the number 2 traces its roots back to the Brahmin Indians, who wrote "2" as two horizontal lines. (wikipedia.org)
  • Following the release of their limited edition "back to basics" cover album Covers 2 (2010), which was intended for "fans and friends" and released in a limited edition manner in a way that would only appeal to fans and friends, the duo wanted to release an album with fan participation. (wikipedia.org)
  • human
  • PT2399 dissociated HIF-2 (an obligatory heterodimer of HIF-2α-HIF-1β) in human ccRCC cells and suppressed tumorigenesis in 56% (10 out of 18) of such lines. (nih.gov)
  • Search
  • In optimization, 2-opt is a simple local search algorithm first proposed by Croes in 1958 for solving the traveling salesman problem. (wikipedia.org)
  • approach
  • Here we use a tumourgraft/patient-derived xenograft platform to evaluate PT2399, a selective HIF-2 antagonist that was identified using a structure-based design approach. (nih.gov)
  • main
  • HIF-2 has been implicated in angiogenesis and multiple other processes, but angiogenesis is the main target of drugs such as the tyrosine kinase inhibitor sunitinib. (nih.gov)
  • last
  • At 21:08 GMT, two hours after the last manoeuvre to remove it from geosynchronous orbit, GOES 2 was commanded to deactivate its communications system, preventing future ground commands being sent to it. (wikipedia.org)