1984 embryo. Medical search. Frequent questions

Naive human pluripotent stem cells (hPSCs) can be used to generate mature human cells of all three germ layers in mouse-human chimeric embryos. (nature.com)
Here, we describe a protocol for generating mouse-human chimeric embryos by injecting naive hPSCs converted from the primed state. (nature.com)
Fig. 7: NGS quantification of human DNA in mouse-human chimeric embryos. (nature.com)
Transient inhibition of mTOR in human pluripotent stem cells enables robust formation of mouse-human chimeric embryos. (nature.com)
Researchers in Jun Wu's lab compare normal mouse embryos (left) to horse-mouse chimeric embryos (right) to identify barriers to interspecies chimerism. (the-scientist.com)

Dr. Hinrichs' laboratory produced the first cloned foal in North America and developed many of the techniques that have supported the growth of ICSI and in vitro embryo production as a clinical tool for equine reproductive management worldwide. (univet.hu)
In vitro embryo production in buffaloes: from the laboratory to the farm. (nih.gov)

Nagl (1978, 1981, 1987) has suggested the term endocycle rather than endomitosis, and D'Amato (1984) has adopted the term endomitotic and endoreduplication to distinguish between those that produce polyploid and polytene nuclei, respectively. (scielo.br)

deBelle, I. and Mak, A.S. Isolation and characterization of tropomyosin kinase from chicken embryo. (enzyme-database.org)
Montgomery, K. and Mak, A.S. In vitro phosphorylation of tropomyosin by a kinase from chicken embryo. (enzyme-database.org)

Embryonic defects are much more extreme in germline clones, where the majority of mutant embryos die during embryogenesis and do not form cuticle, implying a strong chem maternal contribution. (peerj.com)

Two years ago, Shao, a mechanical engineer with a flair for biology, was working with embryonic stem cells, the kind derived from human embryos able to form any cell type. (technologyreview.com)
The southern ground cricket, Allonemobius socius (Scudder), is an ideal animal for studying mechanisms that regulate embryonic diapause because adult females can produce either diapause or non-diapause embryos. (biologists.com)
3,4 The zygote and cells derived from the first two cellular divisions constitute the most primitive cells (totipotent cells) that are capable of forming the embryo and the embryonic annexes (e.g. placenta, amniotic membranes etc). (bvsalud.org)

That's when he landed on a website called The Virtual Human Embryo and found some microscope photos of ten-day old human embryos shortly after implantation, fused to the uterine wall. (technologyreview.com)
Rieger[ 4 ] inferred that the pre-implantation bovine embryo undergoes an intensified period of cellular synthetic processes which require appropriate substrates for production of energy and reducing equivalents in the form of nicotinamide-adenine dinucleotide phosphate. (biomedcentral.com)
ABSTRACT We carried out a prospective randomized trial on 220 couples with nontubal factor infertility to compare pregnancy rates and implantation rates after zygote intrafallopian transfer (ZIFT) and uterine embryo transfer (UET). (who.int)

1988. Antagonistic effect of zinc in lead treated developing chick embryos. (cdc.gov)
Clarke, P.G.H. (1984) Identical populations of phagocytes and dying neurons revealed by intravascularly injected horseradish peroxidase, and by endogenous glutaraldehyde-resistant acid phosphatase in the brains of chick embryos. (karger.com)
Chu-Wang, I.W., R.W. Oppenheim (1978) Cell death of motoneurons in the chick embryo spinal cord. (karger.com)
Effects of 1,1-bis (p-chlorophenyl)-2,2,2-trichloroethane (DDT) on gonadal development in the chick embryo: a histological and histochemical study. (cdc.gov)
Histological and histochemical techniques were used to examine the effects of 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane (50293) (DDT) exposure on two distinct stages in chick embryos: a period during primordial germ cell (PGC) migration (after 5 days of incubation), and the midstage of gonadal development (after 12 days of incubation). (cdc.gov)
There was no significant difference in the number of PGCs aggregating in the gonadal area of 5 day chick embryos exposed to DDT. (cdc.gov)
There was no abnormal external development of the chick embryos. (cdc.gov)

Stem cells can be coaxed to self-assemble into structures resembling human embryos. (technologyreview.com)
In this microscope movie, filmed over four days, stem cells self-organize in ways that mimic a human embryo. (technologyreview.com)
Had they somehow made a real human embryo from stem cells? (technologyreview.com)
This year, for example, researchers in Cambridge, U.K., built a convincing replica of a six-day-old mouse embryo by combining two types of stem cells. (technologyreview.com)
One result already from the Michigan team: dramatic close-up video of stem cells self-organizing into structures that mimic embryos. (technologyreview.com)

Established naive hPSCs are injected into mouse blastocysts, which produce E17.5 mouse embryos containing 0.1-4.0% human cells as quantified by next-generation sequencing of 18S ribosomal DNA amplicons. (nature.com)
The synchronization and ovulatory responses of Sangsari cross bred ewes and metabolism of energy substrates in 8-cell stage embryos to hatched blastocysts stage produced in vitro or in vivo were investigated. (biomedcentral.com)
The production of CO2 from glucose by sheep embryos has been determined[ 3 ] and results have indicated that little glucose is utilized by the embryos of sheep and that blastocysts derived from oocytes, matured and fertilized in vitro , oxidized glucose at a lower rate than those developed in vivo . (biomedcentral.com)

What's more, research on real human embryos is dogged by abortion politics, restricted by funding laws, and limited to supplies from IVF clinics. (technologyreview.com)
Beliefs about the sanctity of life lie at the heart of all the ethical debates on embryo experiments, abortion and euthanasia. (christian.org.uk)
Abortion was legalised in 1967, then in 1990 there were debates on making it legal to carry out experiments which destroy human embryos. (christian.org.uk)

Others contained embryos that had died in the egg at varying stages, possibly from chilling or desertion but, particularly in the earlier years of the programme, some of these failures may have been due to the higher levels of the three main organochlorines (DDE, HEOD and PCBs) that were often found in the eggs. (britishbirds.co.uk)
The larger embryo appeared normal, with nothing external to indicate its cause of death, although chilling and constriction of movement through proximity to its dead sibling in the latter stages are likely causes. (britishbirds.co.uk)

Although these chemicals were formerly present to some degree in all avian specimens, no developmental anomalies or mutations were detected in embryos during this period. (britishbirds.co.uk)

This ontogenetic increase in metabolism of non-diapause insects is blocked during diapause, such that metabolic rate is only 36% of the rate measured for 15 days developing embryos. (biologists.com)
Calorimetric-respirometric(CR) ratios of -353 (day 3) to -333 (day 7) kJ mol -1 O 2 are consistent with embryos that are aerobically recovering from hypoxia, but are inconsistent with an ongoing anaerobic contribution to metabolism. (biologists.com)
Surgical embryo recovery was performed on Days 4 and 6 after onset of estrus (Day 0) and recovered embryos were subjected to comparative metabolism studies with in vitro derived embryos at the same stage of development. (biomedcentral.com)
The first marked increase in the metabolism of glucose by ovine embryos was detected in compact morula stage, but there was no significant increase in the oxidation of glucose after the morula stage. (biomedcentral.com)

The protocol is suitable for studying the development of hPSCs in mouse embryos and may facilitate the generation of human cells, tissues and organs in animals. (nature.com)
Recording and contextualizing the science of embryos, development, and reproduction. (asu.edu)
Published data on the development of embryos of birds in the wild are scarce and the topic has only recently become of interest within the scientific community. (britishbirds.co.uk)
According to our findings, apoptosis seems to be the most frequently observed type of PCD, but it is not the exclusive type of morphological cell death during the development of axial structures in human embryos. (karger.com)
Gastrulation is often referred to as the 'black box' period of human development, because legal restrictions prevent the culture of human embryos in the lab beyond day 14, when the process starts. (scitechdaily.com)
Respiration rate increases 6.3-fold during 15 days of post-oviposition development in embryos of the Southern ground cricket, Allonemobius socius . (biologists.com)
In addition embryos at day 3 have high levels of lactate that decrease as development proceeds up to day 7. (biologists.com)
We've seen embryo testing developed to allow people to avoid passing on serious inherited diseases to any children they might have, the development of, and advancements in, egg freezing, and laws passed and updated to reflect the changing face of fertility medicine. (hfea.gov.uk)

While the pattern of oxidation was similar among in vitro and in vivo derived embryos, a low pyruvate to lactate ratio was the preferred substrate of embryos derived in vitro . (biomedcentral.com)

Fig. 6: Equipment and tools needed to perform embryo transfers. (nature.com)
To compare the pregnancy outcomes between physiologic saline and G-Rinse medium solution for cervical mucus washing, in fresh elective single-embryo transfers (ET) in women under the age of 37. (springer.com)

We analyzed the morphological features of dying cells in the developing axial structures of 5 human embryos between 5 and 8 weeks of postovulatory age. (karger.com)
The embryo-like structures, the team soon determined, are not complete and couldn't become a person. (technologyreview.com)

Superfusing 3-day embryos with O 2 enriched air (40% O 2 ) forces these metabolic indicators toward a more aerobic poise, but only partially. (biologists.com)

Green is posterior part similar to tail-end of an embryo, magenta is anterior part similar to developing heart cells, grey marks DNA. (scitechdaily.com)
If ligation is done somewhat later, partial embryos develop in the anterior portion suggesting that a time-dependent spreading of some factors is required for pattern formation in anterior egg regions. (silverchair.com)

In vitro studies have shown that 2-ME itself evokes no toxic responses, either in Sertoli cell culture 9 or in rat whole embryo culture, whereas MAA does. (bmj.com)

While in Rome, he also earned a doctorate at the Alphonsian Academy, devoting his dissertation to the subjects of in vitro fertilization and embryo transfer. (catholicworldreport.com)
Using physiologic saline solution can be a good alternative approach for ectocervical washing during embryo transfer in selected population because of its lower costs, easy accessibility, and common use. (springer.com)
Embryo transfer (ET) is among the final crucial steps determining the success of assisted reproductive technologies (ART). (springer.com)
therefore, embryos can stick to the wall of the transfer catheter and might be retained. (springer.com)
Synchronization of estrus followed by induction of ovulation are basic techniques in all embryo transfer programs. (biomedcentral.com)

We think that the developmental cues that exist in the pig will help to guide the human cells inside the porcine embryo. (the-scientist.com)

Our paper reviewed data from many labs on the temporal and spatial patterns of expression of homeobox genes in mouse embryos. (the-scientist.com)

In the 12 day group, DDT exposed embryos had a male/female ratio of 22:27 compared to 15:8 for controls. (cdc.gov)

During gastrulation, three distinct layers of cells are formed in the embryo that will later give rise to all the body's major systems: the ectoderm will make the nervous system, mesoderm the muscles, and endoderm the gut. (scitechdaily.com)

Some philosophers adopt a "gradualist" approach - saying that personhood begins a certain period of time after conception depending on the characteristics or functions of the embryo. (christian.org.uk)

Scientists at the ARC Institute of Animal Physiology announced their creation of sheep-goat hybrids known as geeps in 1984 (2). (the-scientist.com)
Scientists painstakingly removed tissue from one embryo and grafted it into another embryo (3). (the-scientist.com)

Current research is directed on the establishment of early pregnancy, late pregnancy and parturition as well as gamete and embryo preservation in domestic animals with main emphasis on the equine species. (univet.hu)
In 1984, the Warnock report identified the need for principles and limits to govern fertility treatment and human embryo research and recommended an independent body be created to make sure clinics operated within these boundaries. (hfea.gov.uk)

This limit was set to fall at the stage where the embryo can no longer form a twin. (scitechdaily.com)
During stage 13 (embryo is 28 days old), the trachea and lung buds become more evident as the esophagus, respiratory tract, and tracheoesophageal septum elongates. (medscape.com)

However, these models may behave differently from human embryos when the cells start to differentiate. (scitechdaily.com)

A fraction of these mutant embryos have lethal head involution or dorsal open phenotypes, and have an extended phenocritical period. (peerj.com)

Complete the form below by 1 August 1984, attach a symposium explanation of about 200 words, a list of tentative speakers and their topics and send to: David Di1cher, Department of Biology, Indiana University, Jordan Hall 033, Bloomington, IN 47405. (botany.org)

That's been difficult to do because normal embryos don't keep growing more than about a week in a lab. (technologyreview.com)

The model resembles some key elements of an embryo at around 18-21 days old and allows the researchers to observe the processes underlying the formation of the human body plan never directly observed before. (scitechdaily.com)

This rare case of twin embryos in a wild bird is discussed in the context of a wider study, which looked at the levels of organochlorines in wild birds' eggs. (britishbirds.co.uk)

Embryos with strongly disrupted apico-basal polarity do not develop, and result in lethal mutant phenotypes where only small pieces of cuticle are synthesized. (peerj.com)
Gastruloids do not have the potential to develop into a fully-formed embryo. (scitechdaily.com)

Superovulation ensures recovery of multiple embryos during one estrous cycle, thus allowing us to maximally exploit the female germ pool. (biomedcentral.com)

larger numbers were present in exposed embryos. (cdc.gov)
Ovaries of exposed embryos contained a significantly larger amount of ALP activity than controls. (cdc.gov)

The main conclusion of the Warnock Report was that human embryos should have 'special status' only after 14 days when a rudimentary nervous system ('the primitive streak') has developed. (christian.org.uk)
The report claims to be more concerned with how it is right to treat the human embryo. (christian.org.uk)

Abstract A Peregrine Falcon egg, collected from a nest in North Wales in 1980 after it failed to hatch, was found to contain two fully developed embryos. (britishbirds.co.uk)
It was found to contain two apparently full-term embryos, both covered in the usual white down, with death likely happening just one to two days from hatching. (britishbirds.co.uk)

Like the original allele, a fraction of mutant embryos die with cuticular defects, notably head involution and dorsal closure defects. (peerj.com)

The distribution and amount of acid- phosphatase (AP) and alkaline-phosphatase (ALP) were similar in exposed and control embryos at 5 days. (cdc.gov)

Mitotic activity of PGCs in DDT exposed and control embryos was not substantially different. (cdc.gov)
After 12 days, there was an absence or reduction of AP activity in the ovaries of exposed embryos. (cdc.gov)
There was no reduction in the mitotic activity of PGCs in the gonadal area of exposed embryos at 5 days. (cdc.gov)

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