Genome-wide gene-gene interaction analysis using single nucleotide polymorphisms (SNPs) is an attractive way for identification of genetic components that confers susceptibility of human complex diseases. (biomedcentral.com)
We performed genotyping of 19 single nucleotide polymorphisms (SNPs) by Sequenom MassARRAY. (hindawi.com)
Previous study found that single nucleotide polymorphisms (SNPs) in nucleotide excision repair (NER) are associated with progression-free survival, including ERCC1, ERCC6, POLD2, POLE, and XPA [ 15 , 16 ]. (hindawi.com)
For each candidate gene, solitary nucleotide polymorphisms (SNPs) have been recognized centered on its functional (n = dos,663) and you can physical annotation (n = 10,649). (costavergel.com.ar)
20223
2022). Molecular Basis Of Specificity And Deamidation Of Eif4a By Burkholderia Lethal Factor 1. (ukm.my)
2022 May 1, In: Journal of Lipid Research. (lu.se)
Adults from the 2022, the number of reported TB cases increased to 52 ( 1 ). (cdc.gov)
Nucleoside1
Synthesis of 8-hydroxy and 8-mercapto derivatives of acyclic adenine nucleoside and nucleotide analogs. (cas.cz)
Sequences3
More generally, RNA design addresses the generation of sequences of nucleotides targeting a given biological function. (dagstuhl.de)
Phylogenetic analysis of virus protein 1 sequences indicated emergence of a new topotype within serotype O, East Africa 4. (blogspot.com)
10. Wayan Suardana I. Analysis of Nucleotide Sequences of the 16S rRNA Gene of Novel Escherichia coli Strains Isolated from Feces of Human and Bali Cattle. (ijcrr.com)
Gene4
Deletions in the 5′-end of this construct showed that the elements responsible for cAMP responsiveness lie within a 242-base-pair fragment of the gene promoter (nucleotides −236/+6 relative to transcription start). (aspetjournals.org)
This de novo assembly of a red clover transcriptome from leaf material of droughted and non-droughted plants provides a rich source for gene identification, single nucleotide polymorphisms (SNP) and short sequence repeats (SSR). (biomedcentral.com)
The gene EXO1 (exonuclease 1) was located at the 1q42 to q43 chromosomal region, a RAD2 nuclease family and encoding 846-amino acid protein [ 17 ]. (hindawi.com)
Single Nucleotide Polymorphisms in the Allene Oxide Synthase 2 Gene Are Associated With Field Resistance to Late Blight in Populations of Tetraploid Potato Cultivars. (mpg.de)
Sequence4
We defined a core genome multilocus sequence typing scheme comprising 2,038 loci and demonstrated its congruence with whole-genome single-nucleotide polymorphism variation. (cdc.gov)
Sequence-dependent coordination of alkali ions to the nucleotide bases in the minor groove of AT-tract B-DNA has recently been inferred from X-ray crystallography, solution NMR and computer simulations. (lu.se)
Author Manuscript genomic DNA sequence of interest that lies next to a protospacer adjacent motif (PAM) matching the sequence NGG5-12, 14 (Supplementary Fig. 1). (cdc.gov)
Anisotropic rotation of amino groups in canonical nucleotide bases. (org.ua)
Topological features of potential energy hypersurface of canonical nucleotide bases. (org.ua)
Single3
We have previously reported that a single nucleotide polymorphism (SNP) in leptin receptor (LEPR), present in up to 50% of people, influenced CDI-induced neutrophil CXCR2 expression and tissue neutrophilia. (frontiersin.org)
To mitigate these problems, we have designed an algorithmic approach called MetaGenomicAssembly by Merging (MEGAMerge) to recursively utilize a number of different Kmer based assemblies and combine the results into a single, merged contig set ( Figure 1 ). (nature.com)
Single nucleotide polymorphism (SNP) genotyping as basis for developing a PCR-based marker highly diagnostic for potato varieties with high resistance to Globodera pallida pathotype Pa2/3. (mpg.de)
Protein2
Phylogenetic analysis of the virus protein (VP) 1 region of FMD viruses has been used extensively to investigate the molecular epidemiology of the disease worldwide. (blogspot.com)
Hypothetical Protein Identifies A Remote Ortholog Of Burkholderia Lethal Factor 1. (ukm.my)
20201
1. Chen S, Cooper N, Müller M, Bein G, Sachs UJ (2020) Piperacillin-dependent anti-platelet antibodies are a relevant, easy to confirm differential diagnosis in patients with rapid-onset thrombocytopenia. (uni-giessen.de)
Amino2
Accession M0001 Systematic name Allele 1: g.31469G>T, c.1279G>T, p.E381X Systematic name Allele 2: g.IVS18+1G>A Original code BHC Description Allele 1: point mutation in the exon 11 leading to a Description premature stop codon Description Allele 2: point mutation in the intron 18 leading to an Description amino acid change and an inframe deletion of 28 amino acids Date 29-Jan-2003 (Rel. (lu.se)
Accession M0003 Systematic name Allele 1 and 2: g.31734T>C, c.1544T>C, p.L469P Original code SaE Description Allele 1 and 2: point mutation in the exon 11 leading to Description an amino acid change in the NACHT domain Date 31-Jan-2003 (Rel. (lu.se)
Genetic1
Despite the limited nucleotide polymorphism of PvMSP4, significant genetic differentiation among the three major parasite populations was detected. (psu.edu)
Resistance3
The choice of [HA535 trade name] to treat antiretroviral-experienced patients with HIV-1 infection should be based on individual viral resistance testing and/or the treatment history of the patient. (who.int)
4 While men and women, 2 with higher rates of 7.7% and 10.8% resistance to azithromycin has also increased global y, 1 among men who have sex with men at two different sites resistance to the dual therapy remains low. (who.int)
1 The WHO a Antimicrobial Resistance Surveillance Reference Laboratory, Research Institute for Tropical Medicine, Muntinlupa, Philippines. (who.int)
Infection5
however, the protection conferred by vaccination or infection is usually serotype specific and sometimes incomplete within a serotype (1-3). (blogspot.com)
Here, we used felid alphaherpesvirus 1 (FHV-1), a close relative of human alphaherpesvirus 1 (HHV-1) that similarly causes ocular herpes, to characterize the host-targeted effects of raltegravir on corneal epithelial cells during an alphaherpesvirus infection. (microbiologyresearch.org)
Oral lactoferrin prevents body weight loss and increases cytokine responses during herpes simplex virus type 1 infection of mice. (microbiologyresearch.org)
HA535 trade name] is indicated in combination with other antiretroviral medicinal products for the treatment of human immunodeficiency virus (HIV-1) infection in patients weighing 30 kg or more. (who.int)
Consideration should be given to official guidelines for prevention and treatment of HIV-1 infection (e.g. issued by WHO). (who.int)
Exon2
The majority of the haplotype diversity was restricted to the two short tetrapeptide repeat arrays in exon 1 and 2, respectively. (psu.edu)
Selection and neutrality tests indicated that exon 1 and the entire coding region of PvMSP4 were under purifying selection. (psu.edu)
Viral1
It has a high mutation rate because the viral RNA-dependent RNA polymerase lacks proofreading ability, resulting in 7 immunogenically distinct serotypes (O, A, C, Southern African Territories [SAT] 1, SAT 2, SAT 3, and Asia 1) and numerous and constantly evolving variants showing a spectrum of antigenic diversity. (blogspot.com)
Metabolism1
2-year data releases planned for the metabolism (1,5,6). (cdc.gov)
Derivatives1
In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat). (microbiologyresearch.org)
Molecular2
In sum, our data indicate that IL-1β is a key molecular mediator that communicates between gastro-intestinal tract (i.e. site of CDI) and bone marrow (i.e. primary neutrophil reservoir) and regulates the intensity of CDI-induced tissue neutrophilia by modulating CXCR2 expression. (frontiersin.org)
1. Atlas R. M., Sayler G., Burlage R. S., and Bej A. K. Molecular approaches for environmental monitoring of microorganisms. (ijcrr.com)
Activation1
Germline mutations resulted in lung cancer pathogenesis by the constitutive activation of proto-oncogenes, such as the members of the EGFR (ERBB), MYC, and RASfamilies, PIK3CA, NKX2-1, and ALK [ 11 , 14 ]. (hindawi.com)
Results1
Although CDC recommends broth-based methods for routine first-line DST of MTBC isolates, the results obtained by the reference agar proportion method (except for pyrazinamide, in which MGIT was performed) are shown in Table 1. (cdc.gov)
Journal1
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 59 (1): 102712. (uni-giessen.de)
Data2
Assembly of metagenomic samples is a very complex process, with algorithms designed to address sequencing platform-specific issues, (read length, data volume, and/or community complexity), while also faced with genomes that differ greatly in nucleotide compositional biases and in abundance. (nature.com)
The rapidly evolving state of Next Generation Sequencing (NGS) data has led to the development of a multitude of de novo and reference-based assembly tools 1 . (nature.com)
Laboratory1
The participants were asked to indicate the primary classification of their laboratory (Figure 1). (cdc.gov)
Nutritional1
Osteoporosis, a provide information on the health and acid-base balance, osmotic pressure, and disease affecting more than 28 million nutritional status of the civilian, normal water balance (1,4,6-8). (cdc.gov)
Type1
The major forms of MD include Duchenne MD (DMD), Becker MD (BMD), limb-girdle MD (LGMD), facioscapulohumeral dystrophy (FSHD), myotonic dystrophy type 1 (DM1), myotonic dystrophy type 2 (DM2), congenital MD (CMD), oculopharyngeal MD (OPMD), distal MD (DMD), and Emery-Dreifuss MD (EDMD). (medscape.com)
12 nucleotides located in the 3' end of the 20 nt gRNA targeting region. (cdc.gov)
Diseases3
This is believed to increase susceptibility to diseases of the crown, such as crown rot [ 1 ]. (biomedcentral.com)
The fact that, for several complex diseases, the recurrence risk ratio decreases quicker than 1/2 as the relatedness decreases implies the involvement of non-additive interactions in their etiology [ 2 , 3 ]. (biomedcentral.com)
Lung cancer is one of the most common diseases and one of the leading causes of cancer-related mortality in the world [ 1 ]. (hindawi.com)
Models1
Given the, recently established, NP-Hardness of the problem, even for minimal energy models [1], many of those algorithmic predictions are either heuristics, exponential-time or based on a variety of machine learning techniques. (dagstuhl.de)