1 protein early growth response protein 1. Medical search. Frequent questions

Hier sind EGR1 Proteine mit einem spezifischen Protein-Typ zu finden. (antikoerper-online.de)
In this study, we report a central role of the transcription factor, early growth response-1 (EGR1), in the regulation of HDAC inhibitor-induced apoptotic cell death in synovial sarcoma. (nature.com)
EGR-1 (Early growth response protein 1) also known as ZNF268 (zinc finger protein 268) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene . (wikipedia.org)
These MAPKs increase the expression or activity of several transcription factors such as early growth response protein 1 (EGR1) cJUN cFOS and activating Bay 65-1942 transcription factor 2 (ATF2) mediating and synthesis (28). (immune-source.com)
Nucleolar function of EGR1 is strictly linked to the expression of nucleolar proteins such as nucleophosmin (B23) and alternative reading frame (p14ARF). (biomedcentral.com)

Several immediate-early genes have been shown to be induced in the rodent circadian pacemaker, the suprachiasmatic nucleus, by retinal illumination at night. (nih.gov)
We found that the acidic domain of MZF-1 and the heparin-binding domain of Elk-1 facilitate the heterodimeric interaction between the two genes before the complex formation binds to the PKCα promoter. (oncotarget.com)
This abrogated expression of the decidual marker genes, insulin like growth factor binding protein 1 ( IGFBP1 ) and prolactin ( PRL ), and prevented adoption of decidual cell morphology. (bioone.org)
In response FOXO1 modulates genes associated with autophagy cell cycle and DNA repair (9-13). (immune-source.com)
Background: Healthy individuals on the lower end of the insulin sensitivity spectrum also have a reduced gene expression response to exercise for specific genes. (elsevierpure.com)
Both genes are highly conserved, and their proteins are thought to have 2 functions: (1) formation of a bridge or scaffold between the DNA-binding transcription factors and the RNA polymerase II complex and (2) serving as histone acetyltransferases that open the chromatin structure, a process essential for gene expression. (medscape.com)
The expression levels of genes involved in neuronal and oligodendrocyte maturation, and angiogenic and transport functions were al-tered, reflecting enhanced brain maturation in response to IGF-1 treatment. (lu.se)
Treatment had no effect on Iba1 + microglia or regional brain weights and did not affect motor development or the expression of genes related to IGF-1 signaling. (lu.se)
To reduce the risk of analyzing cell line- pathway can be divided into distinct stages based on the specific features, we used several representative cell lines for recombination status of the Ig genes and on the expression each of four major stages in B cell development: pro-B, pre-B, pattern of surface markers and the presence of intracellular proteins [1- 6]. (lu.se)

NFAT2, as an important transcriptional promoter, regulates expression of TNF-α, myc proto-oncogene protein (c-myc), cyclooxygenase-2 (COX-2), Fas ligand (FasL) and also generates crosstalks with ERK/MAPK pathway and AKT/GSK3b signaling, which achieves its control of the cell fate [7-12]. (researchsquare.com)
CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms. (uams.edu)
The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells. (uams.edu)
The fermentation stress response protein Aaf1p/Yml081Wp regulates acetate production in Saccharomyces cerevisiae. (1library.org)
The TRAP enzyme primarily regulates the activity of a protein called osteopontin, which is produced in bone cells called osteoclasts and in immune cells. (medlineplus.gov)

The function of the protein is not completely understood, but WDCP has been identified in a fusion protein with anaplastic lymphoma kinase found in colorectal cancer. (wikipedia.org)
WDCP protein domains include two tryptophan-aspartic acid repeat sites, multiple phosphorylation sites, and a domain that interacts with the hemopoietic cell kinase. (wikipedia.org)
Recent reports demonstrate that the expression of protein kinase C alpha (PKCα) in triple-negative breast cancer (TNBC) correlates with decreased survival outcomes. (oncotarget.com)
The mitogen-activated protein kinase homolog, WNK lysine deficient protein kinase 1 (WNK1), is activated downstream of epidermal growth factor receptor during decidualization. (bioone.org)
gene transcription primarily by signaling through protein kinase C (PKC) (28). (immune-source.com)
PKC activates Bay 65-1942 several mitogen activated protein kinase (MAPK) cascades resulting in the phosphorylation and activation of p38 cJun N-terminal kinases (JNK) and extracellular-signal regulated kinases (ERK) (29). (immune-source.com)
Generally, these receptors explain their function on the cell membrane where, after the binding with growth factors or neuregulin undergo to homo or hetero oligomerization with the activation of the intrinsic tyrosine kinase activity and the subsequent recruitment of proteins involved in the cytoplasmic signalling pathways. (biomedcentral.com)

At last, the mRNA and protein expression of NFAT2, Egr2, FasL, COX-2 and c-myc in carcinoma and adjacent tissues was investigated. (researchsquare.com)
Furthermore, NFAT2 participates in the early growth response factor 2 (Egr2)-regulated anergic phenotype which impairs the migration and invasion of leukaemia cells [16]. (researchsquare.com)
Recently, we have shown that the transcription factor Early Growth Response 2 (Egr2) is critical in controlling the anergic state by regulating the expression of DGK-α and -ζ. (bmj.com)
Gene expression profiling and Egr2 ChIP-Seq analysis revealed multiple Egr2-driven cell surface proteins in T cell anergy, including LAG-3, CRTAM, and 4-1BB. (bmj.com)
In this study we used Egr2 targets as well as other previously defined molecules of T cell dysfunction, PD-1 and TIM-3, to characterize T cells in the context of the murine B16.SIY melanoma model. (bmj.com)
FACS and qPCR revealed subpopulations of CD8+ TILs expressing Egr2 in which PD-1 and LAG-3 are enriched. (bmj.com)

It is a nuclear protein and functions as a transcriptional regulator. (antikoerper-online.de)
The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies. (nature.com)
Here we compare transcriptional responses to physiological DNA breaks with responses to genotoxic DNA damage induced by ionizing radiation. (biomedcentral.com)
We identified a central lymphocyte-specific transcriptional response common to both physiologic and genotoxic breaks, which includes many lymphocyte developmental processes. (biomedcentral.com)
Comparing these transcriptional responses provides a greater understanding of the mechanisms cells use in the differentiation between types of DNA damage and the potential consequences of different sources of damage. (biomedcentral.com)
These genome wide transcriptional responses are very tightly regulated and complex. (biomedcentral.com)
While it is known that genotoxic agents, such as IR, activate transcriptional programs involved in maintaining the integrity of the genome, we also want to investigate whether or not the genotoxic breaks could affect lymphocyte-specific maturation transcriptional responses similar to those we observed following RAG-induced physiological DSBs. (biomedcentral.com)
By comparing the transcriptional responses to both types of DNA damage, we can compare the similarities in the responses to damage as well as the differences induced by genotoxic damage. (biomedcentral.com)
CBP and EP300 are ubiquitously expressed homologous proteins that act as transcriptional co-activators. (medscape.com)

During ribosomal RNA processing, ribosomal proteins are incorporated into the pre-ribosomal subunits to form the mature 40S and 60S subunits. (biomedcentral.com)

The liver is a major site for synthesis, storage and redistribution of carbohydrates, proteins and lipids. (aging-research.group)
These studies suggest that FOXO1 suppresses gonadotropin synthesis impartial of direct DNA binding likely through protein complex formation with transcription factors important for gonadotropin synthesis such as paired-like homeodomain. (immune-source.com)
Here, Neuregulin 1 mediated proliferative stimuli, promotes ErbB3 relocalization from the nucleolus to the cytoplasm and increases pre-rRNA synthesis. (biomedcentral.com)
Thus, the control of ribosome assembly and protein synthesis is essential for the survival of cancer cells. (biomedcentral.com)
Akt pathways have effects on apoptosis, protein synthesis, metabolism and cell cycle. (springer.com)
AMPK pathways inhibit biosynthetic pathways with energy consumption, such as protein, fatty acid and glycogen synthesis. (springer.com)
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men. (dashofeast.com)
This response does not require de novo protein synthesis, but involves early events in canonical brassinolide signaling. (cas.cz)
Brain protein synthesis was measured using in vivo. (lu.se)
Brain protein synthesis was measured using in vivo labeling with [2H5] phenylalanine. (lu.se)
Cerebellar protein synthesis was increased by 19% at day 5 and 14% at day 9 after IGF-1 treatment. (lu.se)

Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation. (uams.edu)
Region-spe-cific quantification of IHC labeling showed that IGF-1 treatment promoted neuronal differentiation, increased subcorti-cal myelination, and attenuated synaptogenesis in a region-dependent and time-dependent manner. (lu.se)
Exposures to environmental contaminants early in life are of particular importance, because the reproductive system is undergoing an intricately orchestrated process of growth and differentiation. (cdc.gov)

WDCP exhibits increased protein expression in endocrine tissues, and well as the kidney and urinary bladder. (wikipedia.org)
1996). Expression of Egr-1 correlates with the transformed phenotype and the type of viral latency in EBV genome positive lymphoid cell lines. (nature.com)
EGR-1 has also been found to regulate the expression of VAMP2 (a protein important for synaptic exocytosis ). (wikipedia.org)
This study shows that the expression of both myeloid zinc finger 1 (MZF-1) and Ets-like protein-1 (Elk-1) correlates with PKCα expression in TNBC. (oncotarget.com)
FOXO1 protein Bay 65-1942 has been recognized in murine and rat gonadotrope cells (30 33 While FOXO1 protein expression has not been characterized in human pituitary FOXO1 mRNA levels were found to be decreased seven fold in human null cell and gonadotrope pituitary tumors (34). (immune-source.com)
My primary focus has been on the regulatory elements that support the expression of neuropeptides such as Substance-P and Galanin in regions of the nervous system that include the dorsal root ganglia, the hypothalamus and the amygdala where these peptides are known to regulate the inflammatory response, nutrient selection and mood respectively. (elsevierpure.com)
Conclusions: These results indicate that transcription factor gene expression responses to exercise depend highly on insulin sensitivity in healthy people. (elsevierpure.com)
Other transcription factors, such as Mohawk ( Mkx ) or early growth response ( Egr ), maintain Scx expression and extracellular matrix formation during fibrillogenesis. (techscience.com)
The inhibition of wingless and int-related protein signaling is necessary and sufficient to induce the expression of Scx . (techscience.com)
Our results suggest that the co-expression of LAG-3, PD-1, 4-1BB, and perhaps CRTAM may identify a critical subpopulation of dysfunctional TILs that are specific for tumor antigens and contribute to an immune suppressive tumor microenvironment. (bmj.com)
E) Expression of pqbp1 and ncam mRNA in the neural plate of early neurula embryos. (xenbase.org)

An early growth response transcription factor that has been implicated in regulation of CELL PROLIFERATION and APOPTOSIS. (harvard.edu)
EGR-1 is a mammalian transcription factor . (wikipedia.org)
EGR-1 is an important transcription factor in memory formation. (wikipedia.org)
The role of the early growth response-1 (EGr-1) transcription factor is thought to be essential for ethanol-induced fatty liver injury in mice. (medscape.com)
FOXO1 was also expressed in immortalized murine gonadotrope-derived cell lines: ?T3-1 cells which only express CGA and represent an immature gonadotrope lineage and in L?T2 cells which express CGA LHB and FSHB (30 33 35 36 In gonadotrope cells FOXO1 overexpression suppressed transcription of both human and rodent basal and GnRH stimulated Bay 65-1942 and (30-32). (immune-source.com)

Our functional analysis revealed that the molecular signature of En2 -/- cerebellum and hippocampus shares convergent pathological pathways with ASD, including abnormal synaptic transmission, altered developmental processes and increased immune response. (biomedcentral.com)
Genotoxic damage causes robust alterations to pathways associated with B cell activation and increased proliferation, suggesting that genotoxic damage initiates not only the normal B cell maturation processes but also mimics activated B cell response to antigenic agents. (biomedcentral.com)
Although the presence of tumor-infiltrating lymphocytes (TILs) indicates an endogenous anti-tumor response, immune regulatory pathways can subvert the effector phase and enable tumor escape. (bmj.com)
A fetus is vulnerable not only because of the rapid development and growth that are occurring, but also because it possesses immature and underdeveloped excretion pathways, low levels of chemicalbinding proteins, and an underdeveloped blood-brain barrier that is unable to protect the nervous system from toxic exposures. (cdc.gov)

WDCP protein isoform 1 is 721 amino acids in length. (wikipedia.org)
Compositional analysis of WDCP Isoform 1 shows no extremely high or low levels of particular amino acids. (wikipedia.org)
The human EGR-1 protein contains (in its unprocessed form) 543 amino acids with a molecular weight of 57.5 kDa , and the gene is located on the chromosome 5 . (wikipedia.org)

Several members of the Epidermal Growth Factor Receptor (EGFR) family, have been identified in the nucleus and nucleolus of many cancer cells, but their function in these compartments remains unexplored. (biomedcentral.com)

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. (oncotarget.com)

This may be related to mitochondrial proteins that regulate apoptosis and necrosis and that are shown to be induced in mouse fatty liver models. (medscape.com)
Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma. (uams.edu)

OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration. (1library.org)

Blocking the formation of the heterodimer by transfection of MZF-1 60-72 or Elk-1 145-157 peptide fragments at the MZF-1 / Elk-1 interface decreases DNA-binding activity of the MZF-1 / Elk-1 complex at the PKCα promoter. (oncotarget.com)
The activity of this enzyme is under the control of two main factors, UBF and SL1 both components of the complex that stabilizes RNA Pol I on rDNA promoter [ 1 , 2 ]. (biomedcentral.com)

Preliminary data suggest that DP cells could suppress T cell proliferation in vitro and promote tumor growth in vivo. (bmj.com)

The WDCP isoform 1 is encoded by mRNA-WD repeat and coiled-coil containing, transcript variant 1. (wikipedia.org)
The protein sequence for WDCP Protein Isoform 1 is shown below. (wikipedia.org)
Protein sequence of WDCP protein isoform 1. (wikipedia.org)

Myelinating Schwann cells form a myelin sheath around a single axon and express high levels of myelin-related proteins and messenger RNA (mRNA). (medscape.com)

Rapid growth and division of cells in tumors are correlated with intensive nucleolar metabolism as a response to oncogenic factors overexpression. (biomedcentral.com)

Consistent with this notion, SIY-Kb pentamer staining revealed that the vast majority of CD8+ T cells specific for this model antigen expressed LAG-3, PD-1, and 4-1BB. (bmj.com)
Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma. (uams.edu)

WD Repeat and Coiled-coiled containing protein (WDCP) is a protein which in humans is encoded by the WDCP gene. (wikipedia.org)

NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses. (uams.edu)
Spondyloenchondrodysplasia with immune dysregulation (SPENCDI) is an inherited condition that primarily affects bone growth and immune system function. (medlineplus.gov)
In addition, affected individuals often have abnormal immune cells that cannot grow and divide in response to harmful invaders such as bacteria and viruses. (medlineplus.gov)
As a result, osteopontin is abnormally active, prolonging bone breakdown by osteoclasts and triggering abnormal inflammation and immune responses by immune cells. (medlineplus.gov)
An overactive immune system leads to increased susceptibility to autoimmune disorders and impairs the body's normal immune response to harmful invaders, resulting in frequent infections. (medlineplus.gov)

Exposure of both hamsters and mice to light pulses early and late in the subjective night caused increased ZIF268 immunoreactivity in the region of the suprachiasmatic nucleus that receives retinal innervation. (nih.gov)
Beside its function in the nervous system, there is significant evidence that EGR-1 along with its paralog EGR-2 is induced in fibrotic diseases has key functions in fibrinogenesis and is necessary for experimentally induced fibrosis in mice. (wikipedia.org)
1-dimensional version of the nasal passages have the same inspira- carcinogen in rats and mice. (cdc.gov)
2000. The effect of raloxifene on the uterine weight response in immature mice exposed to 17- estradiol, 1,1,1-trichloro-2,2- bis ( p -chlorophenyl)ethane, and methoxychlor. (cdc.gov)

The second most common form of CMT1 (CMT1B) and some cases of Déjerine-Sottas syndrome were found to be associated with mutations in the myelin protein zero ( MPZ ) gene on chromosome 1. (medscape.com)
For instance, myelin protein zero mutations are associated CMT1B, Déjerine-Sottas syndrome, and the axonal CMT2 phenotype. (medscape.com)
Diagnostic analysis of the Rubinstein-Taybi syndrome: five cosmids should be used for microdeletion detection and low number of protein truncating mutations. (medscape.com)

GnRH binds to the GnRH receptor (GnRHR) a G-protein coupled receptor around the cell surface of gonadotropes (27). (immune-source.com)
More recently, my lab has also studied the effects of regulatory polymorphisms on the regulation of the cannabinoid-1 receptor gene (CNR1) with a view to gaining a better understanding of cannabinoid pharmacogenomics. (elsevierpure.com)
Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2. (uams.edu)
We showed that the IGF-1 receptor was widely distributed in the brain and largely coexisted with immature neurons. (lu.se)

1998). p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. (nature.com)
2004). Inhibition of cell growth by EGR-1 in human primary cultures from malignant glioma. (nature.com)
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo. (uams.edu)

EGR-1 recruits the TET1 protein that initiates a pathway of DNA demethylation . (wikipedia.org)

In SSc, pulmonary disease can exist as a heterogeneous combination of pulmonary fibrosis and pulmonary arterial hypertension (PAH), but the pathogenic mechanisms that induce different pulmonary responses are poorly understood. (ersjournals.com)

The origins of the fibroblasts and their activation remain debated and are probably multiple ( fig. 1 ) [ 8 ]. (ersjournals.com)
Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival. (uams.edu)

The crystal structure of DNA bound by the zinc finger domain of EGR-1 was solved in 1991, which greatly aided early research in zinc finger DNA-binding domains. (wikipedia.org)

The prevalence of Rubinstein-Taybi syndrome in the general population is approximately 1 case per 300,000 persons and is as high as 1 case per 10,000 live births. (medscape.com)

1,3 Genetics is shown to have a strong influence in the development of schizophrenia. (psychiatrist.com)

Cancerous growth is characterized as the uncontrolled multiplication and spread of the body's particular cells causing infection and addresses one of the greatest medical care issues for humanity and requests a proactive procedure for fix. (researchsquare.com)
These subsequent effects are reversed by transfection with full-length PKCα, confirming that the MZF-1/Elk-1 heterodimer is a mediator of PKCα in TNBC cells. (oncotarget.com)
Here we compare the response of developing B cells to both physiologic and genotoxic DSBs. (biomedcentral.com)
As a continuation of this line of research, and given the putative role of brain glial cells in mediating antidepressant responses the present study investigated early effects of vortioxetine on hippocampal microvasculature and Vascular Endothelial Growth Factor (VEGF) and astrocytes and microglia cells. (au.dk)
They have proinflammatory functions: they produce effector molecules (reactive oxygen and nitrogen intermediates) and inflammatory cytokines (IL-1 β , TNF α , and IL-6) and participate as inducer and effector cells in polarized Th1 responses. (hindawi.com)
2000. A metabolite of methoxychlor, 2,2-bis( p hydroxyphenyl)-1,1,1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme. (cdc.gov)

They contribute to homeostatic tissue remodelling during foetal life [ 1 , 2 ] and in several tissues in the adult. (hindawi.com)

[ 10 , 11 ] This duplication is believed to be in the peripheral myelin protein 22kD ( PMP22 ) gene, and overexpression of the gene product appears to be causative, since a gene dosage effect has been demonstrated. (medscape.com)
Now a large and ever increasing number of genetic subtypes has been described, and major advances in molecular and cellular biology have clarified the understanding of the role of different proteins in the physiology of peripheral nerve conduction in health and in disease. (medscape.com)

Early Growth Response Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)

Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis. (uams.edu)

23(1): 441, 2023 Oct 31. (bvsalud.org)
42(1): 25, 2023 Nov 02. (bvsalud.org)

ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma. (uams.edu)
A hormone-responsive C1-domain-containing protein At5g17960 mediates stress response in Arabidopsis thaliana. (1library.org)

These results suggest genotoxic damage may induce a unique cancer-prone phenotype and processes mimicking activated B cell response to antigenic agents, as well as the normal B cell maturation processes. (biomedcentral.com)
Título: "6-(4-metil-pent-3-enil)-1,4-naftoquinona induce efectos antiproliferativos mediados por la producción de ros en células de cáncer de mama. (anid.cl)

In response to environmental cues they display a proinflammatory (M1) or an alternative anti-inflammatory (M2) phenotype. (hindawi.com)
The locus of Rubinstein-Taybi syndrome is located on band 16p13.3, which includes a gene encoding a binding protein for cyclic adenosine monophosphate-response element binding protein (CBP) ( CREBBP or CBP gene) that is responsible for the phenotype of Rubinstein-Taybi syndrome. (medscape.com)

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. (antikoerper-online.de)
The DNA-binding domain of EGR-1 consists of three zinc finger domains of the Cys 2 His 2 type. (wikipedia.org)
The amino acid structure of the EGR-1 zinc finger domain is given in this table, using the single letter amino acid code. (wikipedia.org)

Indeed, several human diseases are characterized by attenuated repair responses and imbalances in the inflammatory response with increased number of infiltrating macrophages [ 3 - 5 ]. (hindawi.com)

Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma. (uams.edu)
Pigs were treated with 2.25 mg/kg/d recombinant human IGF-1/IGF binding protein-3 complex from birth until day 5 or 9 before the collection of brain samples for quantitative immunohistochemistry (IHC), RNA sequencing, and quantitative PCR analyses. (lu.se)

[ 1 ] and by Tooth in England. (medscape.com)

[ 1 ] Tripodi et al reported that in nonalcoholic fatty liver disease (NAFLD), a procoagulant imbalance progresses from steatosis to metabolic cirrhosis, which may be caused by an increase in factor VIII and a reduction of protein C. (medscape.com)
Data from animal studies and clinical studies support the role of proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) in the early stages of fatty liver, as well as in alcoholic steatohepatitis. (medscape.com)
Polyglutamine-binding protein 1 ( PQBP1 ) is an RNA-splicing factor that, when mutated, in humans causes Renpenning syndrome, an X-linked intellectual disability disease characterized by severe cognitive impairment, but also by physical defects that suggest PQBP1 has broader functions in embryonic development. (xenbase.org)
Very preterm infants show low levels of insulin-like growth factor-1 (IGF-1), which is associated with postnatal growth restriction and poor neurologic outcomes. (lu.se)

Macrophages participate in all the different phases of tissue repair: they can promote phagocytosis of cellular debris and apoptotic neutrophils and produce cytokines that may help orchestrate the healing response. (hindawi.com)
Using cesarean-delivered preterm pigs as a model of preterm infants, we investi-gated the effects of supplemental IGF-1 on motor function and on regional and cellular brain development. (lu.se)

We compared spontaneous and light-evoked levels of the immediate-early gene protein ZIF268 (NGFI-A) in the Syrian hamster and C57BL/6J mouse suprachiasmatic nucleus. (nih.gov)

In conclusion, the data show that supplemental IGF-1 promotes brain maturation in newborn preterm pigs. (lu.se)

Chemicals and Drugs8

Phenomena and Processes2

Egr15

Genes9

Regulates5

Kinase7

EGR26

Transcriptional9

Ribosomal proteins1

Synthesis11

Differentiation3

Expression11

Transcription5

Pathways4

Amino Acids3

Epidermal growth f1

20221

Apoptosis2

Extracellular1

Promoter2

Proliferation1

Isoform3

MRNA1

Metabolism1

Antigen2

Humans is encoded1

Immune5

Mice4

Mutations3

Receptor4

Inhibition3

Pathway1

Pulmonary1

Activation2

19911

Prevalence1

Genetics1

Cells6

Tissues1

Peripheral2

MeSH1

Tumor growth1

20232

Mediates2

Induce2

Phenotype2

Zinc3

Inflammatory response1

Recombinant2

Tooth in England1

Factor4

Cellular2

ZIF2681

Maturation1