Colitis
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Nitrobenzenes
Colon
Peroxidase
Anilino Naphthalenesulfonates
Intestinal Mucosa
Disease Models, Animal
Rats, Sprague-Dawley
Mice, Inbred BALB C
Picryl Chloride
Molecular Structure
Stereoisomerism
Carboxylic Acids
Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.
Structure-Activity Relationship
Rats, Wistar
Cinnamates
Cinnamates are organic compounds that contain a cinnamic acid moiety, widely used in pharmaceutical and cosmetic industries as esters, with various applications ranging from UV absorbers to local anesthetics and antimicrobial agents.
Glycyrrhetinic Acid
Triterpenes
Dose-Response Relationship, Drug
Hydrogen-Ion Concentration
Magnetic Resonance Spectroscopy
Benzoic Acid
Caffeic Acids
A class of phenolic acids related to chlorogenic acid, p-coumaric acid, vanillic acid, etc., which are found in plant tissues. It is involved in plant growth regulation.
ortho-Aminobenzoates
Benzoic acids, salts, or esters that contain an amino group attached to carbon number 2 or 6 of the benzene ring structure.
Esters
Chlorogenic Acid
Coumaric Acids
Ipomoea batatas
Inhibitory Concentration 50
Chromatography, High Pressure Liquid
Amination
Chemistry Techniques, Synthetic
Indicators and Reagents
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Tumor Necrosis Factor-alpha
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.