The act of killing oneself.

The unsuccessful attempt to kill oneself.

Provision (by a physician or other health professional, or by a family member or friend) of support and/or means that gives a patient the power to terminate his or her own life. (from APA, Thesaurus of Psychological Index Terms, 8th ed).

Genes that are used transgenically, i.e., via GENE TRANSFER TECHNIQUES to induce CELL DEATH.

A risk factor for suicide attempts and completions, it is the most common of all suicidal behavior, but only a minority of ideators engage in overt self-harm.

Small-arms weapons, including handguns, pistols, revolvers, rifles, shotguns, etc.

Behavior in which persons hurt or harm themselves without the motive of suicide or of sexual deviation.

A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.

The killing of one person by another.

Disruption of structural continuity of the body as a result of the discharge of firearms.

Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.

A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.

Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

The act or practice of killing or allowing death from natural causes, for reasons of mercy, i.e., in order to release a person from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)

Conceptual response of the person to the various aspects of death, which are based on individual psychosocial and cultural experience.

Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Physicians appointed to investigate all cases of sudden or violent death.

An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Toxic asphyxiation due to the displacement of oxygen from oxyhemoglobin by carbon monoxide.

The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.

Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.

The state of not being engaged in a gainful occupation.

Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.

An ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

The act or practice of killing for reasons of mercy, i.e., in order to release a person or animal from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)

An enzyme that catalyzes the conversion of ATP and thymidine to ADP and thymidine 5'-phosphate. Deoxyuridine can also act as an acceptor and dGTP as a donor. (From Enzyme Nomenclature, 1992) EC 2.7.1.21.

The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.

An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE.

Active euthanasia of a patient at the patient's request and/or with the patient's consent.

The right of the patient or the patient's representative to make decisions with regard to the patient's dying.

Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.

Refers to the whole process of grieving and mourning and is associated with a deep sense of loss and sadness.

Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.

A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.

Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.

Permanent roads having a line of rails fixed to ties and laid to gage, usually on a leveled or graded ballasted roadbed and providing a track for freight cars, passenger cars, and other rolling stock. Cars are designed to be drawn by locomotives or sometimes propelled by self-contained motors. (From Webster's 3d) The concept includes the organizational and administrative aspects of railroads as well.

The interrelationship of psychology and religion.