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Frustration: The motivational and/or affective state resulting from being blocked, thwarted, disappointed or defeated.Anger: A strong emotional feeling of displeasure aroused by being interfered with, injured or threatened.Irritable Mood: Abnormal or excessive excitability with easily triggered anger, annoyance, or impatience.Temperament: Predisposition to react to one's environment in a certain way; usually refers to mood changes.Protein Folding: Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.Thermodynamics: A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)Qualitative Research: Any type of research that employs nonnumeric information to explore individual or group characteristics, producing findings not arrived at by statistical procedures or other quantitative means. (Qualitative Inquiry: A Dictionary of Terms Thousand Oaks, CA: Sage Publications, 1997)Attitude of Health Personnel: Attitudes of personnel toward their patients, other professionals, toward the medical care system, etc.Focus Groups: A method of data collection and a QUALITATIVE RESEARCH tool in which a small group of individuals are brought together and allowed to interact in a discussion of their opinions about topics, issues, or questions.Physician-Patient Relations: The interactions between physician and patient.Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Interviews as Topic: Conversations with an individual or individuals held in order to obtain information about their background and other personal biographical data, their attitudes and opinions, etc. It includes school admission or job interviews.