Carbodiimide cross-linking reagent.

Carbodiimides are chemical compounds containing two nitrogen atoms and one carbon atom, often used in biochemistry for the formation of amide bonds, particularly in peptide synthesis and cross-linking of proteins or other biomolecules.

CME-Carbodiimide, also known as 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide, is a heterocrosslinking agent used in the modification of biomolecules for various research and medical applications, facilitating the formation of amide bonds between carboxylic acid and amine groups.

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.

A carbodiimide that is used as a chemical intermediate and coupling agent in peptide synthesis. (From Hawley's Condensed Chemical Dictionary, 12th ed)