A synthetic tetracycline derivative with similar antimicrobial activity.
Substances that reduce the growth or reproduction of BACTERIA.
Closely congeneric derivatives of the polycyclic naphthacenecarboxamide. (Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1117)
A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
Compounds that inhibit the enzyme activity or activation of MATRIX METALLOPROTEINASES.
A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.
Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss.
A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
Pharmacological agents destructive to nematodes in the superfamily Filarioidea.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
A member of the MATRIX METALLOPROTEINASES that cleaves triple-helical COLLAGEN types I, II, and III.
Therapy with two or more separate preparations given for a combined effect.
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.