Antitreponemal Agents: Agents used to treat infections with bacteria of the genus TREPONEMA. This includes SYPHILIS & YAWS.Treponema pallidum: The causative agent of venereal and non-venereal syphilis as well as yaws.Treponemal Infections: Infections with bacteria of the genus TREPONEMA.Neurosyphilis: Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)Syphilis Serodiagnosis: Serologic tests for syphilis.Syphilis: A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.