Neuregulin directly decreases voltage-gated sodium current in hippocampal ErbB4-expressing interneurons.
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(+info )Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?
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(+info )Flecainide reduces Ca(2+) spark and wave frequency via inhibition of the sarcolemmal sodium current.
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(+info )Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation.
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(+info )Phenytoin inhibits the persistent sodium current in neocortical neurons by modifying its inactivation properties.
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(+info )Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability.
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(+info )Antagonism of lidocaine inhibition by open-channel blockers that generate resurgent Na current.
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(+info )Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties.
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