AnatomyOrganismsDiseasesChemicals and DrugsPhenomena and Processes
Penicillium chrysogenumSphingosineAcyltransferasesGlycerol-3-Phosphate O-AcyltransferaseLysophospholipidsPhosphatidylcholine-Sterol O-AcyltransferaseDiacylglycerol O-AcyltransferaseSterol O-AcyltransferaseLecithin Acyltransferase Deficiency1-Acylglycerophosphocholine O-AcyltransferasePhosphotransferases (Alcohol Group Acceptor)Receptors, LysosphingolipidPropylene GlycolsAcyl Coenzyme ASphingolipids1-Acylglycerol-3-Phosphate O-AcyltransferaseCeramidesReceptors, LysophospholipidEsterificationAcylationCeramidasesCholesterol EstersSphingomyelinsCholesterolApolipoprotein A-IMicrosomesGlycerophosphatesKinetics

HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging. (25/53)

 (+info)

TMSG-1 and its roles in tumor biology. (26/53)

TMSG-1 is a newly discovered tumor metastasis suppressor gene, which plays important roles in promoting apoptosis and inhibiting invasion and metastasis of tumor cells. The inhibitory function of TMSG-1 in tumor cells may be related to vacuolar H+-ATPase and ceramide, but the underlying mechanism remains unknown. Studies on TMSG-1 are limited worldwide, and only a research group in Shanghai and our group have recently studied on it. As a new research field, the function of TMSG-1 remains to be explored. This review discusses the discovery of TMSG-1, structure of its encoded protein, its roles and possible mechanism in inhibiting tumor invasion and metastasis.  (+info)

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis. (27/53)

 (+info)

Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis. (28/53)

 (+info)

Causal modeling using network ensemble simulations of genetic and gene expression data predicts genes involved in rheumatoid arthritis. (29/53)

 (+info)

A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation. (30/53)

 (+info)

Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels. (31/53)

 (+info)

Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network. (32/53)

 (+info)