AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
RNA CleavageRNAEndoribonucleasesRNA, CatalyticRNA, ViralRNA, Small InterferingBase SequenceMolecular Sequence DataNucleic Acid ConformationRNA Processing, Post-TranscriptionalRNA, RibosomalDNA, CatalyticRNA-Induced Silencing ComplexRNA SplicingRNA EditingRNA, MessengerRNA, BacterialRNA, Double-StrandedRibonucleasesDNA-Directed RNA PolymerasesRNA InterferenceRibonuclease HSubstrate SpecificityRNA StabilityRibonuclease IIIRibonuclease, PancreaticAmino Acid SequenceRNA Polymerase IIOligoribonucleotidesRNA PrecursorsHydrolysisRNA, FungalRNA, Ribosomal, 28SCatalysisBinding SitesTranscription Factors, GeneralKineticsArgonaute ProteinsTranscriptional Elongation FactorsDNA CleavageRNA VirusesEscherichia coliTranscription, GeneticMutationModels, MolecularTemplates, GeneticPoly ARNA FoldingBase PairingRNA-Binding ProteinsCleavage Stage, OvumRNA HelicasesHeLa CellsRNA, AntisenseProtein BiosynthesisProtein BindingProtein Structure, TertiaryRNA, TransferCations, DivalentRNA, Small NuclearSequence Homology, Amino AcidRecombinant ProteinsRNA, UntranslatedCatalytic DomainRNA CapsNucleic Acid HybridizationManganeseDNA PrimersSequence Analysis, RNAConserved SequenceRNA, PlantMagnesiumCell LineSaccharomyces cerevisiaeEndopeptidasesRNA, ProtozoanDNAMicroRNAsProtein Processing, Post-TranslationalRNA ReplicaseRNA Ligase (ATP)RNA, NeoplasmCrystallography, X-RaySaccharomyces cerevisiae ProteinsDEAD-box RNA HelicasesRNA, GuideRNA Polymerase IIIPlasmidsPeptide FragmentsmRNA Cleavage and Polyadenylation FactorsRNA, Ribosomal, 18SRNA Polymerase IRNA, NuclearCaspasesMolecular WeightElectrophoresis, Polyacrylamide GelFurinProtein PrecursorsSerine EndopeptidasesRNA, Ribosomal, 23S

Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage. (25/95)

 (+info)

Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. (26/95)

 (+info)

Motoneurons secrete angiogenin to induce RNA cleavage in astroglia. (27/95)

 (+info)

Kinetic analysis of aptazyme-regulated gene expression in a cell-free translation system: modeling of ligand-dependent and -independent expression. (28/95)

 (+info)

Inhibition of HIV-1 Integrase gene expression by 10-23 DNAzyme. (29/95)

HIV Integrase (IN) is an enzyme that is responsible for the integration of the proviral genome into the human genome, and this integration step is the first step of the virus hijacking the human cell machinery for its propagation and replication. 10-23 DNAzyme has the potential to suppress gene expressions through sequence-specific mRNA cleavage. We have designed three novel DNAzymes, DIN54, DIN116, and DIN152, against HIV-1 Integrase gene using Mfold software and evaluated them for target site cleavage activity on the in vitro transcribed mRNA. All DNAzymes were tested for its inhibition of expression of HIV Integrase protein in the transiently transfected cell lines. DIN116 and DIN152 inhibited IN-EGFP expression by 80 percent and 70 percent respectively.  (+info)

A strategy for developing a hammerhead ribozyme for selective RNA cleavage depending on substitutional RNA editing. (30/95)

 (+info)

A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity. (31/95)

 (+info)

Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing. (32/95)

 (+info)