Guanine Nucleotide Exchange Factorsras Guanine Nucleotide Exchange Factorsras ProteinsDiglyceridesSon of Sevenless ProteinsSOS1 ProteinLeukemia, Mast-CellDiacylglycerol KinasePhorbol EstersTetradecanoylphorbol AcetateKeratin-10ThymocytesGTP-Binding Protein alpha Subunit, Gi2Signal TransductionEF Hand MotifsProtein TransportReceptors, Antigen, T-CellDNA-Binding Proteinsrap1 GTP-Binding ProteinsPhospholipase C gammaExtracellular Signal-Regulated MAP KinasesMastocytosisProtein Kinase Crap GTP-Binding ProteinsMice, KnockoutThymus GlandMAP Kinase Signaling SystemEnzyme ActivationCell LinePrecursor T-Cell Lymphoblastic Leukemia-LymphomaCell MembraneCell DegranulationBryostatinsT-LymphocytesPhorbol 12,13-DibutyrateReceptors, Antigen, B-CellProtein Kinase C-deltaEpidermisLymphocyte ActivationJurkat CellsMitogen-Activated Protein Kinase 1Genes, rasProto-Oncogene Proteins p21(ras)PropidiumKidney Tubules, DistalMitogen-Activated Protein KinasesMitogen-Activated Protein Kinase 3Oncogene Protein p21(ras)AutoimmunityNIH 3T3 CellsProto-Oncogene Proteins c-vavCell ProliferationAmino Acid SequenceZAP-70 Protein-Tyrosine KinaseLymphopoiesisMast CellsKeratinocytesProtein Structure, TertiaryImmunoglobulin IsotypesSkin NeoplasmsPhosphorylationEmbryo Culture TechniquesMolecular Sequence DataGuanosine TriphosphateMutationCommon Variable ImmunodeficiencyCell DifferentiationB-LymphocytesGene Knockout TechniquesMice, Inbred C57BLRecombinant Fusion ProteinsCell Cycle CheckpointsPregnancy Complications, CardiovascularMice, TransgenicCarcinogensMice, Mutant StrainsElectrophoresisDNA, ComplementaryMicroscopy, FluorescenceImmunoprecipitationModels, BiologicalTransfectionType C PhospholipasesSequence Homology, Amino AcidCHO CellsMAP Kinase Kinase 4ChickensAlternative SplicingReverse Transcriptase Polymerase Chain ReactionBlotting, WesternDown-RegulationReceptors, IgERNA, Small InterferingProtein BindingCD8-Positive T-LymphocytesImmunoblottingCricetinaeFluorescent Antibody TechniqueFlow CytometryTransgenes