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Pulmonary vein stenosis complicating ablation for atrial fibrillation: clinical spectrum and interventional considerations. (41/87)

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Cautious epoprostenol therapy is a safe bridge to lung transplantation in pulmonary veno-occlusive disease. (42/87)

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First locus for primary pulmonary vein stenosis maps to chromosome 2q. (43/87)

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Idiopathic pulmonary veno-occlusive disease. (44/87)

We report a case of idiopathic pulmonary veno-occlusive disease (PVOD). The patient experienced progressively worsening dyspnea. Heart catheterization revealed severe pulmonary hypertension. High-resolution computed tomography (HRCT) showed diffuse, poorly identified centrilobular ground-glass opacities. Surgical lung biopsy led to the diagnosis of PVOD. A microscopic examination revealed occlusions of pulmonary veins and venules over a wide area with prominent loop-like capillary dilatations. These pathological findings may be correlated with the radiological characteristics of HRCT in this case.  (+info)

Sutureless pericardial repair of total anomalous pulmonary venous connection in patients with right atrial isomerism. (45/87)

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Pulmonary veno-occlusive disease: a case report. (46/87)

The authors present the case of a 22-year-old female patient, white, referred to the cardiovascular outpatient clinic in November 2006 for pulmonary arterial hypertension. Complementary diagnostic exams revealed elevated pulmonary arterial pressure, normal capillary wedge pressure and a reduced cardiac index on invasive hemodynamic study. A high-resolution pulmonary CT scan identified a diffuse ground-glass opacity with a centrilobular pattern, and a marked decrease in CO diffusion on respiratory function assessment. An open lung biopsy was accordingly performed in January 2007, which was compatible with pulmonary arterial hypertension with associated venous lesions: pulmonary veno-occlusive disease. Therapy was begun with oxygen support, warfarin and bosentan (62.5 mg twice a day) Monthly follow-up was maintained, but her clinical and functional status progressively worsened and one year after the diagnosis the patient was admitted to our heart failure clinic for acute right heart failure. She was stabilized with inotropic therapy and diuretics and was subsequently referred to an international pulmonary transplantation center. The authors highlight the diagnostic challenge of this entity and its poor response to medical therapy and dismal prognosis.  (+info)

Pulmonary veno-occlusive disease: recent progress and current challenges. (47/87)

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Pulmonary veno-occlusive disease misdiagnosed as idiopathic pulmonary arterial hypertension. (48/87)

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