Imaging of endolymphatic and perilymphatic fluid after intravenous administration of single-dose gadodiamide.
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To visualize endolymph as bright signal after intravenous injection of single-dose gadodiamide, we shortened the inversion time of heavily T(2)-weighted 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) to 2050 ms. In 14 patients with suspected Meniere's disease, we observed high signal of vestibular endolymph in all ears, including 6 ears without vestibular endolymphatic hydrops. We observed high signal of cochlear endolymph in 17 ears with cochlear endolymphatic hydrops but not 11 ears without cochlear endolymphatic hydrops. (+info)
Perilymph pharmacokinetics of markers and dexamethasone applied and sampled at the lateral semi-circular canal.
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Imaging of Meniere's disease by subtraction of MR cisternography from positive perilymph image.
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To visualize endolymph, perilymph, and bone separately in a single image after intravenous injection of single-dose gadodiamide, we generated a HYDROPS2 image (subtraction of MR cisternography from heavily T(2)-weighted 3-dimensional fluid-attenuated inversion recovery image) in 12 patients with suspected Meniere's disease. The contrast-to-noise ratio of endo- and perilymph did not differ significantly between the HYDROPS2 and previously reported HYDROPS (hybrid of reversed image of positive endolymph signal and native image of positive perilymph Signal) images, and scan time was 40% shorter for the HYDROPS2 than HYDROPS. (+info)
Cochlear pharmacokinetics of cisplatin: an in vivo study in the guinea pig.
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