Enamel and dentine remineralization by nano-hydroxyapatite toothpastes.
(57/97)
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Modifications of bone material properties in postmenopausal osteoporotic women long-term treated with alendronate.
(58/97)
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Biomimetic approach for root caries prevention using a proanthocyanidin-rich agent.
(59/97)
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Non-destructive clinical assessment of occlusal caries lesions using near-IR imaging methods.
(60/97)
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Nondestructive monitoring of the repair of enamel artificial lesions by an acidic remineralization model using polarization-sensitive optical coherence tomography.
(61/97)
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Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible.
(62/97)
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Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength.
(63/97)
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Remineralization of demineralized enamel via calcium phosphate nanocomposite.
(64/97)
Secondary caries remains the main problem limiting the longevity of composite restorations. The objective of this study was to investigate the remineralization of demineralized human enamel in vitro via a nanocomposite containing nanoparticles of amorphous calcium phosphate (NACP). NACP were synthesized by a spray-drying technique and incorporated into a dental resin. First, caries-like subsurface enamel lesions were created via an acidic solution. Then, NACP nanocomposite or a commercial fluoride-releasing control composite was placed on the demineralized enamel, along with control enamel without a composite. These specimens were then treated with a cyclic demineralization/remineralization regimen for 30 days. Quantitative microradiography showed typical enamel subsurface demineralization before cyclic demineralization/remineralization treatment, and significant remineralization in enamel under the NACP nanocomposite after the demineralization/remineralization treatment. The NACP nanocomposite had the highest enamel remineralization (mean +/- SD; n = 6) of 21.8 +/- 3.7%, significantly higher than the 5.7 +/- 6.9% for fluoride-releasing composite (p < 0.05). The enamel group without composite had further demineralization of -26.1 +/- 16.2%. In conclusion, a novel NACP nanocomposite was effective in remineralizing enamel lesions in vitro. Its enamel remineralization was 4-fold that of a fluoride-releasing composite control. Combined with the good mechanical and acid-neutralization properties reported earlier, the new NACP nanocomposite is promising for remineralization of demineralized tooth structures. (+info)