Interacting effects of genioglossus stimulation and mandibular advancement in sleep apnea.
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Morphological changes in the mandible of male mice associated with aging and biomechanical stimulus.
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Titrated mandibular advancement versus positive airway pressure for sleep apnoea.
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An orthodontic-surgical approach to Class II subdivision malocclusion treatment.
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Comparison of mandibular advancement splint and tongue stabilizing device in obstructive sleep apnea: a randomized controlled trial.
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STUDY OBJECTIVES: To compare the efficacy of a mandibular advancement splint (MAS) and a novel tongue stabilizing device (TSD) in the treatment of obstructive sleep apnea (OSA). DESIGN: A randomized crossover design was used. PATIENTS: Twenty-seven patients (20 male, 7 female), recruited from a tertiary hospital sleep clinic. MEASUREMENTS AND RESULTS: The apnea-hypopnea index (AHI) was reduced with MAS (11.68 +/- 8.94, P = 0.000) and TSD (13.15 +/- 10.77, P = 0.002) compared with baseline (26.96 +/- 17.17). The arousal index decreased for MAS (21.09 +/- 9.27, P = 0.004) and TSD (21.9 +/- 10.56, P = 0.001) compared with baseline (33.23 +/- 16.41). Sixty-eight percent of patients achieved a complete or partial response with MAS, compared with 45% with TSD. The Epworth Sleepiness Scale (ESS) score was decreased with MAS (P = < 0.001) and TSD (P = 0.002). Subjective improvements in snoring and quality of sleep were reported, with a better response for MAS than TSD. Compliance was poorer for TSD, and the side effect profiles of the 2 modalities were different. All patients were satisfied with MAS compared to TSD, and 91% of patients preferred the MAS. CONCLUSION: Objective testing showed the MAS and TSD had similar efficacy in terms of AHI reduction. Patients reported improvements with both devices; however, better compliance and a clear preference for MAS was apparent when both devices were offered. Longer term studies are needed to clarify the role of TSD. (+info)
A randomized prospective long-term study of two oral appliances for sleep apnoea treatment.
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Comparative evaluation of the breaking strength of a simple mobile mandibular advancement splint.
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Maintenance of a deep bite prior to surgical mandibular advancement.
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