Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase.
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Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing.
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The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila.
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PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.
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Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency.
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ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1.
(78/339)
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Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes.
(79/339)
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Targeting histone demethylases in cancer therapy.
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