Neuregulin-1NeuregulinsReceptor, Epidermal Growth FactorReceptor, erbB-3Epidermal Growth FactorReceptor, erbB-2Genes, erbBQuinazolinesTransforming Growth Factor alphaSignal TransductionPhosphorylationOncogene Proteins v-erbBCell Line, TumorTyrphostinsBreast NeoplasmsCell LineCell DivisionAntineoplastic AgentsProtein Kinase InhibitorsIntercellular Signaling Peptides and ProteinsAntibodies, Monoclonal, HumanizedTumor Cells, CulturedGenes, erbB-2Protein-Tyrosine KinasesEnzyme ActivationCells, CulturedTransforming Growth FactorsGrowth SubstancesTyrosineAntibodies, MonoclonalLung NeoplasmsGenes, erbB-1Cell ProliferationMolecular Sequence DataImmunohistochemistryMutationProto-Oncogene ProteinsRNA, MessengerTransfectionBlotting, WesternProto-Oncogene Proteins c-aktLigandsMitogen-Activated Protein KinasesPhosphatidylinositol 3-KinasesCarcinoma, Squamous CellAmino Acid SequenceGene Expression Regulation, NeoplasticMice, NudeProtein BindingPhosphotyrosineReceptors, Cell SurfaceExtracellular Signal-Regulated MAP KinasesEnzyme InhibitorsMAP Kinase Signaling SystemCarcinoma, Non-Small-Cell LungMitogen-Activated Protein Kinase 3Down-RegulationKineticsGene AmplificationDrug Resistance, NeoplasmCell MovementEpithelial CellsMitogen-Activated Protein Kinase 13T3 Cellssrc-Family Kinasesras ProteinsCell Transformation, NeoplasticRecombinant ProteinsDose-Response Relationship, DrugBase SequenceAdenocarcinomaEndocytosisProtein Structure, TertiaryReceptor Protein-Tyrosine KinasesApoptosisAdaptor Proteins, Signal TransducingRecombinant Fusion ProteinsCell MembraneProto-Oncogene Proteins c-cblFibroblastsKeratinocytesTumor Markers, BiologicalGRB2 Adaptor ProteinCOS CellsRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionPrecipitin TestsTime FactorsXenograft Model Antitumor AssaysReceptors, EstrogenDimerizationImmunoblottingModels, BiologicalTetradecanoylphorbol AcetateGene ExpressionCell SurvivalPeptidesMembrane ProteinsNeoplasm InvasivenessDrug Synergism