Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation.
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(+info )The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator.
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(+info )Cyclin C and cyclin dependent kinases 1, 2 and 3 in thrombin-induced neuronal cell cycle progression and apoptosis.
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(+info )The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.
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(+info )CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.
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(+info )Revving the Throttle on an oncogene: CDK8 takes the driver seat.
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(+info )Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.
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(+info )Understanding large multiprotein complexes: applying a multiple allosteric networks model to explain the function of the Mediator transcription complex.
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