Purification, crystallization and preliminary x-ray crystallographic studies of RAIDD Death-Domain (DD).
(17/30)
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A cut above the other caspases.
(18/30)
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Characterization of cytoplasmic caspase-2 activation by induced proximity.
(19/30)
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Identification and analysis of dominant negative mutants of RAIDD and PIDD.
(20/30)
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In vitro reconstitution of the interactions in the PIDDosome.
(21/30)
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Activation of caspase-9, but not caspase-2 or caspase-8, is essential for heat-induced apoptosis in Jurkat cells.
(22/30)
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LBH589, a deacetylase inhibitor, induces apoptosis in adult T-cell leukemia/lymphoma cells via activation of a novel RAIDD-caspase-2 pathway.
(23/30)
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Genetic mapping and exome sequencing identify variants associated with five novel diseases.
(24/30)
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