Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.
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Runx1/Cbfbeta2 complexes are required for lymphoid tissue inducer cell differentiation at two developmental stages.
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CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells.
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Core binding factor beta functions in the maintenance of stem cells and orchestrates continuous proliferation and differentiation in mouse incisors.
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miR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies.
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The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.
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Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFbeta-dependent expression of the Wnt antagonist, sclerostin.
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Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells.
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