Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes.
Analysis of cholesterol trafficking with fluorescent probes.
A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.
Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood.
Steroids as central regulators of organismal development and lifespan.
Production of a novel steroid sulfate metabolite [4,4,24-trimethylcholesta-8,14,24(28)-trien-2 alpha,3 beta,11 alpha,12 beta-tetrol 12-acetate, 3-sulfate] by Fusarium species and its biological activity.
(62/116)A novel steroid sulfate, 4,4,24-trimethylcholesta-8,14-24(28)-trien-2 alpha,3 beta,11 alpha,12 beta- tetrol 12-acetate, 3-sulfate, was discovered in Fusarium spp. Forty Fusarium strains belonging to F. sporotrichioides, F. chlamydosporum, E. equiseti, F. acuminatum, F. sambucinum, F. culmorum, and F. graminearum produced the steroid on white corn grits at 25 degrees C for 20 days. This steroid sulfate is one of the more abundant and easily attainable microbial steroids. At a concentration of 160 micrograms/ml, it inhibited the growth of six fungi, two gram-positive bacteria, and an alga, as well as the germination of both wheat and tomato seeds. (+info)
Sterol affinity for phospholipid bilayers is influenced by hydrophobic matching between lipids and transmembrane peptides.
Influence of steroid hormone signaling on life span control by Caenorhabditis elegans insulin-like signaling.