AnatomyDiseases
Central Nervous System Bacterial InfectionsCentral Nervous SystemBacterial Infections

Pharmacokinetics of single-dose daptomycin in patients with suspected or confirmed neurological infections. (33/43)

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Spinal epidural abscess: aetiology, predisponent factors and clinical outcomes in a 4-year prospective study. (34/43)

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Strain-dependent CNS dissemination in guinea pigs after Mycobacterium tuberculosis aerosol challenge. (35/43)

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Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study. (36/43)

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Pharmacokinetics of colistin in cerebrospinal fluid after intraventricular administration of colistin methanesulfonate. (37/43)

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Review of 17 cases of neurobrucellosis: clinical manifestations, diagnosis, and management. (38/43)

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Central nervous system relapse of Whipple's disease. (39/43)

A 50-year-old man presented with a 12 kg weight loss in 8 months. Upper gastrointestinal endoscopy findings showed strong erosion and diffuse bleeding in the duodenum. Histopathological findings showed PAS staining-positive macrophages consistent with Whipple's disease. He was treated with trimethoprim-sulfamethoxazole. His condition initially improved. However, during his 6-year course of treatment he developed a central nervous system relapse. Tropheryma whipplei DNA was detected by a polymerase chain reaction in his cerebrospinal fluid. This relapse was successfully treated with ceftriaxone sodium (CTRX). We considered that as initial therapy for Whipple's disease, it would be important to administer CTRX for at least a few months, due to its high translatability to CSF.  (+info)

Neurologic complications of HIV-1 infection and its treatment in the era of antiretroviral therapy. (40/43)

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