Segmental phenolization for the treatment of ingrown toenails: technique report, follow up of 146 patients, and review of the literature.
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BACKGROUND: Ingrown toenail is a common problem causing significant morbidity. Various procedures used for treating this painful condition were discussed in the literature. OBJETCTIVE: Through a prospective study we aimed to evaluate in a long-term follow-up the efficacy of partial nail plate avulsion combined with phenolic chemical matricectomy for the treatment of Ingrown toenails. METHODS: We recruited outpatient from January 2006 to December 2009; all treated by phenol matricectomy and assured a regular follow up. RESULTS: Consecutive 146 patients with a total of 171 Ingrown toenails were enrolled. There was no significant morbidity and the procedure was tolerated well by all patients. The short-term results were excellent. No severe complications occurred during the 21-month follow-up period. The overall recurrence was 2.7 %. CONCLUSION: Phenol cauterization compared with other surgical ablation techniques may be the treatment of choice of Ingrown toenails. It's an effective technique for the treatment of Ingrown toenails accompanied by less morbidity and lower recurrence rates. (+info)
Comparative studies on the detoxification of aflatoxins by sodium hypochlorite and commercial bleaches.
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Cultures of Aspergillus flavus and aflatoxins were destroyed by a commercial bleach (Clorox; active ingredient, NaOCl) or analytical reagent grade NaOCl at 7.0 x 10(-3) M NaOCl in 5 days. Addition of Clorox or NaOCl at 2.8 x 10(-3) M to the fungal growth medium prior to inoculation completely inhibited the fungal growth. Aflatoxin production was inversely proportional to the logarithm of NaOCl concentration and time of treatment. Clorox and NaOCl were equally effective on aflatoxins, but fungal cells were lysed more readily by Clorox than by NaOCl. Mycelia older than 8 days lysed more readily than younger ones. Most conidia survived concentrations below 1.4 x 10(-3) M. The lowest effective concentration for a 2-hr treatment was 8.8 x 10(-3) M which is well below the Clorox concentration recommended for routine laboratory decontamination of aflatoxins. Mice and rats injected with aflatoxins and aflatoxins incompletely destroyed by Clorox died within 72 hr and had typical liver and kidney damage caused by aflatoxins. However, animals injected with NaOCl or Clorox or Clorox-destroyed aflatoxin extracts survived and showed no obvious liver or kidney damage. (+info)
Corrosive injury to oro-pharynx and esophagus. Eighty-five consecutive cases.
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In 85 consecutive cases of ingestion of caustic material, 70 patients had oral burns, 29 incurred esophageal burns, and in three esophageal stricture developed, requiring repeated dilatation. Management involves early endoscopy to determine the extent of mucosal injury, antibiotics to reduce local or mediastinal infection, and steroids to prevent the chance for esophageal stricture. (+info)
Surgical management of corrosive gastric injuries.
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Four cases of extensive corrosive gastric injury requiring surgical treatment are presented. Appropriate management of this life-threatening entity requires an awareness of its subtle presentation plus a well planned surgical approach. (+info)
Potential occupational health hazards in the microelectronics industry.
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The microelectronics industry is a major user of a wide variety of chemicals and other toxic materials. In the recent past semiconductor manufacturers have located in many countries and brought a new set of challenging clinical problems to occupational physicians. California, an area with a significant history in the statistical study of health and safety in the microelectronics industry, presents some evidence of potential health hazards in the semiconductor manufacturing process. The Semiconductor Industry Study done in California in 1981 explains the application of many toxic materials in the semiconductor manufacturing process, including a variety of solvents, acids, and metals such as arsenic. The Study documents the extensive use of dopant gases, primarily arsine, phosphine and diborane. Further study is necessary to assure the health and safety of microelectronics workers, particularly in the application of dopant gases. (+info)
Caustic burns and carcinoma of the esophagus.
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A history of caustic injury was obtained in 12 of 846 patients with squamous cell carcinoma of the esophagus. The average age was 52.8 years; the interval from injury to development of carcinoma was 45.8 years. Nine of the 12 carcinomas were in the midthoracic segment. Resection was possible in nine patients, with two surviving over ten years. A survey of reported series with this association confirms the increased resection rate and probability of long survival compared with the usual carcinoma of the esophagus. (+info)