Synchronous carotid body and thoracic paraganglioma associated with a germline SDHC mutation. (41/77)

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Important observations made managing carotid body tumors during a 25-year experience. (42/77)

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A case of carotid body paraganglioma and haemangioblastoma of the spinal cord in a patient with the N131K missense mutation in the VHL gene. (43/77)

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Head-and-neck paragangliomas are associated with sleep-related complaints, especially in the presence of carotid body tumors. (44/77)

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Contiguous bilateral head and neck paragangliomas in a carrier of the SDHB germline mutation. (45/77)

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Current concepts in the management of carotid body tumours. (46/77)

OBJECTIVE: To review the current management of carotid body tumours and examine our own experience at the Singapore General Hospital. STUDY DESIGN: Retrospective review. SUBJECTS AND METHODS: Case note review of patients treated by the Department of Otolaryngology Head and Neck Surgery, Singapore General Hospital over a period of nine years from January 1999 to December 2007. RESULTS: There were a total of ten patients. Eight patients underwent surgery with no mortality or major surgical morbidity. Mean follow-up was 3 years and 5 months with no evidence of recurrence. One patient had bilateral tumours and is under surveillance. The last patient had inoperable disease and received radiotherapy. CONCLUSION: Our series has shown that carotid body tumours can be safely removed surgically. If the internal carotid artery needs to be resected, we prefer the use of a Pruitt-Inahara shunt. Radiotherapy is reserved for large inoperable cases or patients not fit for surgery.  (+info)

Imaging carotid body chemodectomas with (6)(8)Ga-DOTA-NOC PET-CT. (47/77)

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Carotid body tumor as a reversible cause of syncope. (48/77)

The causes of syncope are diverse and extensive; carotid body tumors are an extremely rare cause of syncope. These rare neoplasms represent less than 0.5% of all head and neck tumors. The authors present a case of a woman with syncope who was found to have a right-sided carotid body tumor. After surgical resection was performed, she did not have any additional syncopal or near-syncopal events. The authors provide a review of the literature on the natural history, presentation, and preferred management of carotid body tumors. With modern diagnostic tools and treatment options, most patients with this diagnosis can expect to recover fully.  (+info)