Computer-aided detection of endobronchial valves using volumetric CT. (49/132)

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Study of the variability in upper and lower airway morphology in Sprague-Dawley rats using modern micro-CT scan-based segmentation techniques. (50/132)

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Headscarf pin tracheobronchial aspiration: a distinct clinical entity. (51/132)

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Chest computed tomography findings in familial dysautonomia patients: a model for aspiration. (52/132)

BACKGROUND: Lung disease in patients with familia dysautonomia is caused mainly by recurrent aspiration of gastric contents, food and liquids swallowed incorrectly. OBJECTIVE: To describe chest computed tomography findings in patients with familial dysautonomia. METHODS: A retrospective analysis of chest CT findings was performed for 34 FD patients (15 females, 19 males) with a mean age of 18 +/- 12.8 years. RESULTS: The CT revealed bronchial wall thickening (in 94% of the patients), atelectasis (in 73%), ground glass opacities (in 53%), focal hyperinflation (in 44%), fibrosis (in 29%) and bronchiectasis (in 26%). The extrapulmonary abnormalities were scoliosis (79%) and esophageal dilatation (35%). Silent fractures were noted in two vertebral bodies and one rib. CONCLUSIONS: Pulmonary changes were consistent with chronic inflammation in the bronchi and interstitial tissues. Ground glass opacities and fibrosis support the theory that these changes could be due to gastric aspiration. Bronchiectasis is less frequent. Esophageal dilatation with fluid overflow adds to aspiration. Fractures can be asymptomatic and are often missed.  (+info)

Bronchial hyperresponsiveness to methacholine in patients with primary Sjogren's syndrome. (53/132)

The prevalence of bronchial hyperresponsiveness (BHR) to methacholine inhalation in a consecutive series of 21 patients with primary Sjogren's syndrome was studied prospectively. Slight to severe BHR was seen in 12/20 (60%) of the patients. Ten of 12 patients with BHR (83%) had a non-productive cough, wheezing, or intermittent breathlessness. Bronchial hyperresponsiveness was more common in patients with extraglandular symptoms (10/14, 71%) than in those with only glandular symptoms (29%). Spirometrically 29% (6/21) of the patients had 'small airways' disease', and all those had BHR. Of 6/21 (29%) who had diffuse interstitial lung disease, two had BHR. Three of the four patients with obstructive lung function were challenged with methacholine and two of them had BHR. Only two patients with BHR had normal spirometry findings. The data showed that respiratory disease--mostly mild or moderate but even severe bronchial hyperresponsiveness--is commonly seen in patients with primary Sjogren's syndrome.  (+info)

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes. (54/132)

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Endobronchial foreign body removed by rigid bronchoscopy after 39 years. (55/132)

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A differential geometric approach to automated segmentation of human airway tree. (56/132)

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