Efficient cross-coupling of secondary alkyltrifluoroborates with aryl chlorides--reaction discovery using parallel microscale experimentation.
(73/261)
Highly stereoselective synthesis of cis-alkenyl pinacolboronates and potassium cis-alkenyltrifluoroborates via a hydroboration/protodeboronation approach.
(75/261)
Effects of arginine residue introduction upon interaction and complexation behavior of peptide ribonucleic acids (PRNAs) with RNA: synthesis and properties of alpha-containing arginine.
(77/261)
Development and application of a capillary electrophoretic method for the composition analysis of a typical heteropolysaccharide from Codonopsis pilosula NANNF.
(78/261)
A simple capillary electrophoretic method based on 1-phenyl-3-methyl-5-pyrazolon (PMP) derivatization has been developed for simultaneous separation and determination of nine aldoses (xylose, arabinose, glucose, rhamnose, fucose, galactose, mannose, glucuronic acid and galacturonic acid). The separation of PMP-labeled monosaccharide derivatives was carried out in uncoated capillary (48.5 cm x 75 microm i.d.) and under the selected optimum conditions of pH 11.0, 200 mM borate buffer at applied voltage 15 kV and capillary temperature 20 degrees C, the nine PMP-monosaccharides could be perfectly separated from each other within 40 min. Furthermore, the developed method was firstly applied to determine the sugar composition in the polysaccharide isolated from Chinese Codonopsis pilosula. The results showed that C. pilosula polysaccharide was a typically acidic heteropolysaccharide and was composed of arabinose, glucose, rhamnose, galactose, mannose, glucuronic acid and galacturonic acid in the molar contents of 48.1, 103.5, 16.1, 48.5, 7.5, 4.2 and 119.1 microM, respectively. The assay results were satisfactory. (+info)
Micro-solvent cluster extraction using aqueous mixed solvents of ionic liquid.
(79/261)
Organic compounds (2-naphthol, phenol, 4-chlorophenol, 4-nitrophenol, and 1,3,5-naphthalenetrisulfonic acid) were sufficiently separated from mixtures during flow in a fused silica capillary tube (50 microm in i.d. and 45 cm in length) with an aqueous mixed solvent of an ionic liquid, 1-butyl-3-methylimidazolium chloride (BMIM(+)Cl(-)), without a specific separation column. The method is based on micro-solvent cluster formation in aqueous mixed solvents of ionic liquid and preferential solvation of solvent clusters to analytes. The measurement of large angle X-ray scattering (LAXS) of aqueous mixed solvents with an ionic liquid of tetrafluoroborate (BMIM(+)BF(4)(-)) indicated the formation of micro-solvent clusters of water and ionic liquid in the mixed solvent. A neutral polymer (polyvinylpyrrolidone, PVP) enhanced the separation. Polarized or ionic molecules eluted slowly. The theoretical plate numbers were 6320, 22907, 63645, and 37184 for 2-naphthol, phenol, 4-chlorophenol, and 4-nitrophenol, respectively, under the conditions of 1.0 M of BMIM(+)Cl(-) and 0.1 M of PVP; the flow rate was 1 microL min(-1). The separation mechanism is discussed from the viewpoint of the partition of analytes between micro-solvent clusters of water and organic solvent molecules. (+info)
Orthogonal reactivity in boryl-substituted organotrifluoroborates.
(80/261)