AutoimmunityAutoantigensAutoantibodiesSelf ToleranceAutoimmune DiseasesClonal DeletionB-LymphocytesLymphocyte ActivationT-LymphocytesMice, TransgenicImmune ToleranceMice, Inbred NODB-Lymphocyte SubsetsCD4-Positive T-LymphocytesMice, Inbred MRL lprLupus VulgarisDiabetes Mellitus, Type 1Receptors, Antigen, B-CellClonal AnergyAntibodies, AntinuclearMice, Inbred C57BLEncephalomyelitis, Autoimmune, ExperimentalPeripheral ToleranceThymus GlandAdoptive TransferHybridomasLupus Erythematosus, SystemicClone CellsReceptors, Antigen, T-CellT-Lymphocyte SubsetsMyelin Basic ProteinHistocompatibility Antigens Class IISpleenMice, KnockoutAntigen-Presenting CellsEpitopes, T-LymphocyteMice, Inbred NZBMice, Inbred BALB CCD8-Positive T-LymphocytesFlow CytometryReceptors, Antigen, T-Cell, alpha-betaMyelin-Oligodendrocyte GlycoproteinT-Lymphocytes, RegulatoryThymocytesComplementarity Determining RegionsUveitisMyelin Proteolipid ProteinB-Cell Activating FactorMyelin ProteinsGlutamate DecarboxylaseImmunoglobulin Heavy ChainsCell DifferentiationImmunoglobulin MIslets of LangerhansMyelin-Associated GlycoproteinAntigen PresentationMultiple SclerosisPeptide FragmentsH-2 AntigensLymphopeniaCentral ToleranceCells, CulturedImmunoglobulin Variable RegionMice, Inbred StrainsCytokinesImmunoglobulin DLymphocyte CooperationHLA-DR4 AntigenAntigens, CD8snRNP Core ProteinsImmunoglobulin GEpitopes, B-LymphocyteLymphocyte DepletionT-Lymphocytes, Helper-InducerDendritic CellsMajor Histocompatibility ComplexEpitopesAmino Acid SequenceModels, ImmunologicalCD40 LigandAntigens, CD95Molecular Sequence DataDisease Models, AnimalInterleukin-21 Receptor alpha SubunitRats, Inbred LewAntigens, CD4Interferon-gammaDesmoglein 3Antibodies, MonoclonalImmunologic MemoryTh1 CellsPrecursor Cells, B-LymphoidRetinol-Binding ProteinsLupus NephritisLymphocyte CountAntigensGene Rearrangement, B-LymphocyteImmunophenotypingMice, CongenicThymectomy