Parasympathetic effects on cardiac electrophysiology during exercise and recovery in patients with left ventricular dysfunction.
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Segmental conduction block in a low-voltage area suppressed macro-reentrant ventricular tachycardia after surgical repair of tetralogy of Fallot.
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Macro-reentrant ventricular tachycardia (VT) developed in a 20-year-old man, 17 years after surgical repair of tetralogy of Fallot. Activation mapping of the VT revealed its counterclockwise propagation around the right ventricle, and through a critical pathway between a transannular patch and the tricuspid annulus. This critical pathway was 6 cm long and contained myocardium with a normal amplitude, while the area of low voltage was limited adjacent to the transannular patch. A linear lesion was created by radiofrequency energy delivered only to the low voltage area. After ablation, the activation wavefront through the low voltage area was blocked, and VT became non-inducible. (+info)
Intra-His bundle block in second-degree Mobitz I atrioventricular block with right bundle branch block.
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Long-term outcomes in individuals with prolonged PR interval or first-degree atrioventricular block.
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Congenital heart block not associated with anti-Ro/La antibodies: comparison with anti-Ro/La-positive cases.
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Preserved cardiac synchrony and function with single-site left ventricular epicardial pacing during mid-term follow-up in paediatric patients.
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Simultaneous assessment of pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects on atria of chronic atrioventricular block dogs.
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Pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects were simultaneously assessed using chronic atrioventricular block dogs. After application of the patch (9.8 mg/kg), pilsicainide was continuously absorbed through the skin with a C(max) of 0.49 +/- 0.13 microg/ml, while its plasma concentration was kept above the clinically reported minimum effective plasma concentration for 2 - 8 h. Inter-atrial conduction time was significantly prolonged, whereas statistically significant prolongation was not detected in the atrial effective refractory period. Prolongation of the cycle length of atrial fibrillation and anti-fibrillatory action were confirmed. Thus, pilsicainide can be absorbed transdermally to exert long-lasting electropharmacological effects leading to anti-atrial fibrillatory action. (+info)
Mechanism of paroxysmal supraventricular tachycardia with ventriculoatrial conduction block.
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