Comparison between the standardized clinical and laboratory standards institute M38-A2 method and a 2,3-Bis(2-Methoxy-4-Nitro-5-[(Sulphenylamino)Carbonyl]-2H-tetrazolium hydroxide- based method for testing antifungal susceptibility of dermatophytes.
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Dermatophyte infections in patients attending a tertiary care hospital in northern Italy.
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We studied dermatophyte infections in patients attending the Dermatology Outpatients Clinic of S. Matteo hospital Pavia, Italy, during the period 2004-2006. A total of 100 samples were collected from 95 patients; 97 dermatophytes and 3 keratinophylic fungi were isolated. Trichophyton rubrum was the most frequent dermatophyte isolated (42.3%), followed by Microsporum canis (31%), T. mentagrophytes (14.5%) and M. gypseum (9.2%). Less frequently isolated were Epidermophyton floccosum and T. violaceum. The most common dermatophyte infections included tinea corporis, tinea pedis, tinea unguium, tinea capitis and tinea cruris. Zoophilic dermatophytes were most commonly recovered from children and adolescents with tinea capitis and tinea corporis. Anthropophilic species were identified mostly in adults with tinea pedis, tinea cruris and onychomycosis. (+info)
Successful mating of a human isolate of Arthroderma simii with a tester strain of A. vanbreuseghemii.
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An isolate of Arthroderma simii was successfully mated with a tester strain of A. vanbreuseghemii cultured on the plate of simple agar with some hair on it at 27 degrees C. Confirmation of sexual reproduction was made by the detection of hybrids of two parental genotypes. The implications of this result are discussed from the viewpoint of a reevaluation of the species boundaries of dermatophytes. (+info)
Epidemiological survey of dermatophytosis in Tehran, Iran, from 2000 to 2005.
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BACKGROUND: Cutaneous fungal infections are common in Tehran, Iran, and causative organisms include dermatophytes, yeasts and non-dermatophyte molds. The prevalence of superficial mycosis infections has risen to such a level that skin mycoses now affect more than 20-25% of the world's population, making them the most frequent form of infection. AIMS: Our aim was to determine the prevalence of superficial cutaneous fungal infections especially dermatophytosis in our Medical Mycology Laboratory in the Pasteur Institute of Iran, Tehran. METHODS: A total of 17,573 specimens were collected from clinically suspected tinea corporis, tinea cruris, tinea capitis, tinea faciei, tinea pedis, tinea manuum and finger and toe onychomycosis from 2000 to 2005. Patients were referred to our laboratory for direct examination, fungal culture and identification. The incidence of each species was thus calculated. RESULTS: Dermatophytes remain the most commonly isolated fungal organisms, except from clinically suspected finger onychomycosis, in which case Candida species comprise >7% of the isolates. Epidermophyton floccosum remains the most prevalent fungal pathogen and increased incidence of this species was observed in tinea cruris. Trichophyton tonsurans continues to increase in incidence. CONCLUSION: This study identifies the epidemiologic trends and the predominant organisms causing dermatophytosis in Tehran, Iran. These data can be used to ascertain the past and present trends in incidence, predict the adequacy of our current pharmacologic repertoire and provide insight into future developments. Consideration of the current epidemiologic trends in the incidence of cutaneous fungal pathogens is of key importance to investigational effort, diagnosis and treatment. (+info)
NB-002, a novel nanoemulsion with broad antifungal activity against dermatophytes, other filamentous fungi, and Candida albicans.
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