SAR studies for a new class of antibacterial NAD biosynthesis inhibitors.
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Detection of early unfolding events in a dimeric protein by amide proton exchange and native electrospray mass spectrometry.
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Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods.
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An ancestral glutamine-dependent NAD(+) synthetase revealed by poor kinetic synergism.
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Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis.
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A protein microarray-based analysis of S-nitrosylation.
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Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins.
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A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis.
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