Impaired fasting tolerance among Alaska native children with a common carnitine palmitoyltransferase 1A sequence variant. (57/80)

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Brazilian urban population genetic structure reveals a high degree of admixture. (58/80)

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Unusual presentation of hepatitis B serological markers in an Amerindian community of Venezuela with a majority of occult cases. (59/80)

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Piloting the CANRISK tool in Vancouver Coastal Health. (60/80)

INTRODUCTION: Vancouver Coastal Health Authority's Healthy Living Program implemented this pilot study to test and validate the Canadian Diabetes Risk Assessment Questionnaire (CANRISK) developed by the Public Health Agency of Canada as a screening tool for undiagnosed type 2 diabetes mellitus (DM) and prediabetes. Key objectives were to test the feasibility and acceptability of screening urban ethnic groups using the CANRISK, increase awareness of risk factors for DM and preDM and develop resources for lifestyle change. METHODS: The study recruited participants through community groups and churches, intraorganizational emails, primary care clinics and word of mouth. They completed the CANRISK and an oral glucose tolerance test (OGTT) either individually or as part of a group. Groups received a brief diabetes prevention information session. Documents to support lifestyle change were distributed to all participants. RESULTS: Participants (n = 556) were recruited among East Asian, Caucasian, South Asian and Latin American ethnic groups. Of these, 17% had OGTT results in the preDM range and 3% in the DM range. Over 90% of participants reported that the CANRISK wording was clear and that they had received useful information about lowering their diabetes risk. CONCLUSION: The benefit of using an OGTT was in identifying 11% of the sample of participants who had impaired glucose tolerance (IGT) and did not show abnormal fasting plasma glucose (FPG) results. All participants with abnormal laboratory results were provided with follow-up educational interventions in their own language.  (+info)

Ancestral components of admixed genomes in a Mexican cohort. (61/80)

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Exposure to secondhand smoke at home and at work in California. (62/80)

OBJECTIVES: We estimated self-reported secondhand smoke (SHS) exposure in California at home and at work. METHODS: We used data from the 2005 and 2007 California Health Interview Surveys (n=109,809) for home exposure analysis, and we used data from the 2002 and 2005 California Tobacco Surveys (n=12,883) for workplace exposure analysis. Differences in exposure by age, race/ethnicity, and socioeconomic characteristics were assessed using Chi-square tests and multivariate logistic regression analyses. RESULTS: In the home, children had the lowest rates of SHS exposure (3.4%), followed by adolescents (4.7%) and adults (6.0%). For all age groups, Hispanic people had the lowest exposure to SHS at home, and black people of all ages had higher exposure rates than white people. In the workplace, 12.9% of Californians were exposed to SHS. Men had higher rates of exposure than women, and rates declined with age. Hispanic people had the highest rates of SHS exposure at work (19.5%), followed by Asian/Pacific Islanders (10.5%), black people (10.4%), and white people (9.7%). Workplace exposure rates were highest for people who worked in stores or warehouses, followed by plants or factories, restaurants or bars, and vehicles. CONCLUSIONS: Despite many years of tough tobacco-control policies in California, people continue to be exposed to SHS at home and in the workplace. The policies that are already in place, such as smoke-free workplace laws, need to be fully enforced. Interventions for reducing SHS exposure should be targeted to the groups with the greatest exposure rates, including Hispanic people, black people, young adults, and those who work in high-exposure settings.  (+info)

Hypercontrols in genotype-phenotype analysis reveal ancestral haplotypes associated with essential hypertension. (63/80)

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Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. (64/80)

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