Effect of herbal medicine achillea millefolium on plasma nitrite and nitrate levels in patients with chronic kidney disease: a preliminary study. (25/31)

INTRODUCTION: Increased plasma nitric oxide concentration has been supposed as one of the possible mechanisms of bleeding tendency in patients who suffer chronic kidney disease. Nitric oxide-scavenging properties have been reported with some Achillea species. This study was designed to find any possible effect of Achillea millefolium on plasma nitric oxide concentration in these patients. MATERIALS AND METHODS: Thirty-one chronic kidney disease patients were included in this randomized controlled trial, of whom16 received 1.5 g of powdered A millefolium flower 3 days a week for 2 months, and 15 received placebo for the same period. Plasma samples were collected before and after the study period to estimate the effect of A millefolium on plasma nitric oxide metabolites (nitrite and nitrate). RESULTS: Although not statistically significant, plasma nitrite and nitrate concentrations decreased after 2 months' administration of A millefolium (0.82 +/- 0.51 micromol/L to 0.63 +/- 0.42 micromol/L and 50.55 +/- 17.92 micromol/L to 44.09 +/- 17.49 micromole/L, respectively). These concentrations were slightly increased in the placebo group after the study period. CONCLUSIONS: Countercurrent to the placebo group, plasma nitric oxide metabolites were marginally decreased after A millefolium administration in chronic kidney disease patients. Higher doses or longer duration of plant administration may make these changes more significant.  (+info)

Inter- and intra-specific genetic diversity of Iranian yarrow species Achillea santolina and Achillea tenuifolia based on ISSR and RAPD markers. (26/31)

Cultivation and preservation of yarrow has recently attracted wide attention due to its beneficial properties; however, genetic variation of Achillea species is still relatively unknown. We used RAPD and ISSR markers to assess genetic diversity in 16 accessions of yarrow belonging to two species native to Iran. Seven ISSR and nine RAPD primers generated 187 amplified fragments, of which 159 were polymorphic. The similarity coefficient among Achillea tenuifolia accessions ranged from 61 to 86%, and from 40 to 84% among A. santolina accessions. A low similarity was observed between these two species (mean similarity = 0.36%). This low similarity is consistent with their geographical distribution. According to the results of cluster and PCA analyses, the two species completely separated from each other. These markers will aid in the identification of elite genotypes for domestication and breeding programs.  (+info)

Insecticide activity of essential oils of Mentha longifolia, Pulicaria gnaphalodes and Achillea wilhelmsii against two stored product pests, the flour beetle, Tribolium castaneum, and the cowpea weevil, Callosobruchus maculatus. (27/31)

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The effect of hydro-ethanolic extract of Achillea millefolium on muscarinic receptors of guinea pig tracheal smooth muscle. (28/31)

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Mechanisms for success after long-term nutrient enrichment in a boreal forest understory. (29/31)

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Differential growth inhibitory effects of highly oxygenated guaianolides isolated from the Middle Eastern indigenous plant Achillea falcata in HCT-116 colorectal cancer cells. (30/31)

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Polyphenolic composition, antioxidant and antibacterial activities for two Romanian subspecies of Achillea distans Waldst. et Kit. ex Willd. (31/31)

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