Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I. (57/119)

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A targeted mass spectrometry-based approach for the identification and characterization of proteins containing alpha-aminoadipic and gamma-glutamic semialdehyde residues. (58/119)

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Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. (59/119)

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Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells. (60/119)

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L-aspartate: evidence for a role in cone photoreceptor synaptic transmission in the carp retina. (61/119)

A number of putative neurotransmitter substances and their antagonists were applied to the carp retina while intracellular recordings from L-type cone horizontal cells were made. Of all the substances tested, L-aspartate was found to be the most potent agent in depolarizing these horizontal cells in dark-adapted, partially light-adapted, and Co2+-treated retinas. Furthermore, DL-alpha-aminoadipate, an L-aspartate antagonist, blocked the effects of both the endogenous photoreceptor transmitter and exogenously applied L-aspartate on the horizontal cells. The results suggest that L-aspartate and the natural transmitter interact with the same population of postsynaptic receptors in the horizontal cell membrane.  (+info)

A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase. (62/119)

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The measurement of urinary Delta(1)-piperideine-6-carboxylate, the alter ego of alpha-aminoadipic semialdehyde, in Antiquitin deficiency. (63/119)

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Dual-lifetime referencing (DLR): a powerful method for on-line measurement of internal pH in carrier-bound immobilized biocatalysts. (64/119)

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