Toxicity Tests, Acute: Experiments designed to determine the potential toxic effects of one-time, short-term exposure to a chemical or chemicals.Toxicity Tests: An array of tests used to determine the toxicity of a substance to living systems. These include tests on clinical drugs, foods, and environmental pollutants.Toxicity Tests, Subchronic: Experiments designed to determine the potential toxic effects of mid-term (a few months) exposure to a chemical or chemicals.Toxicity Tests, Chronic: Experiments designed to determine the potential toxic effects of a long-term exposure to a chemical or chemicals.Toxicity Tests, Subacute: Experiments designed to determine the potential toxic effects of a short-term (a few weeks) exposure to a chemical or chemicals.Lethal Dose 50: The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.Morinda: A plant genus of the family RUBIACEAE. Members contain iridoid glycosides and ANTHRAQUINONES.Animal Testing Alternatives: Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated for use in place of the use of animals in research or diagnostic laboratories.Water Pollutants, Chemical: Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water.Daphnia: A diverse genus of minute freshwater CRUSTACEA, of the suborder CLADOCERA. They are a major food source for both young and adult freshwater fish.Skin Irritancy Tests: Tests or bioassays that measure the skin sensitization potential of various chemicals.Amphipoda: An order of mostly marine CRUSTACEA containing more than 5500 species in over 100 families. Like ISOPODA, the other large order in the superorder Peracarida, members are shrimp-like in appearance, have sessile compound eyes, and no carapace. But unlike Isopoda, they possess thoracic gills and their bodies are laterally compressed.Toxicology: The science concerned with the detection, chemical composition, and biological action of toxic substances or poisons and the treatment and prevention of toxic manifestations.Artemia: A genus of CRUSTACEA of the order ANOSTRACA, found in briny pools and lakes and often cultured for fish food. It has 168 chromosomes and differs from most crustaceans in that its blood contains hemoglobin.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.
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