Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)History, 16th Century: Time period from 1501 through 1600 of the common era.Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.History, 17th Century: Time period from 1601 through 1700 of the common era.Cemeteries: Areas set apart as burial grounds.Naval Medicine: The practice of medicine concerned with conditions affecting the health of individuals associated with the marine environment.BooksScurvy: An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs.Somalia: Somalia is located on the east coast of Africa on and north of the Equator and, with Ethiopia, Eritrea, Djibouti, and Kenya, is often referred to as the Horn of Africa. It comprises Italy's former Trust Territory of Somalia and the former British Protectorate of Somaliland. The capital is Mogadishu.Societies, Hospital: Societies having institutional membership limited to hospitals and other health care institutions.History, 19th Century: Time period from 1801 through 1900 of the common era.History, 18th Century: Time period from 1701 through 1800 of the common era.L-Gulonolactone Oxidase: An enzyme involved in the metabolism of ASCORBIC ACID and aldarate. It catalyzes the oxidation of L-gulono-1,4-lactone to L-xylo-hex-3-ulonolactone.Vitamins: Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.Starvation: Lengthy and continuous deprivation of food. (Stedman, 25th ed)Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
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