Middle East: The region of southwest Asia and northeastern Africa usually considered as extending from Libya on the west to Afghanistan on the east. (From Webster's New Geographical Dictionary, 1988)Africa, Northern: The geographical area of Africa comprising ALGERIA; EGYPT; LIBYA; MOROCCO; and TUNISIA. It includes also the vast deserts and oases of the Sahara. It is often referred to as North Africa, French-speaking Africa, or the Maghreb. (From Webster's New Geographical Dictionary, 1988, p856)Far East: A geographic area of east and southeast Asia encompassing CHINA; HONG KONG; JAPAN; KOREA; MACAO; MONGOLIA; and TAIWAN.Coronavirus: A genus of the family CORONAVIRIDAE which causes respiratory or gastrointestinal disease in a variety of vertebrates.Coronavirus Infections: Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE).Oman: A sultanate on the southeast coast of the Arabian peninsula. Its capital is Masqat. Before the 16th century it was ruled by independent emirs but was captured and controlled by the Portuguese 1508-1648. In 1741 it was recovered by a descendent of Yemen's imam. After its decline in the 19th century, it became virtually a political and economic dependency within the British Government of India, retaining close ties with Great Britain by treaty from 1939 to 1970 when it achieved autonomy. The name was recorded by Pliny in the 1st century A.D. as Omana, said to be derived from the founder of the state, Oman ben Ibrahim al-Khalil. (From Webster's New Geographical Dictionary, 1988, p890; Oman Embassy, Washington; Room, Brewer's Dictionary of Names, 1992, p391)Saudi ArabiaEar, Middle: The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.QatarArabs: Members of a Semitic people inhabiting the Arabian peninsula or other countries of the Middle East and North Africa. The term may be used with reference to ancient, medieval, or modern ethnic or cultural groups. (From Random House Unabridged Dictionary, 2d ed)JordanKuwaitGermany, EastCamels: Hoofed mammals with four legs, a big-lipped snout, and a humped back belonging to the family Camelidae.Coronaviridae Infections: Virus diseases caused by CORONAVIRIDAE.LebanonIranSyriaAsia: The largest of the continents. It was known to the Romans more specifically as what we know today as Asia Minor. The name comes from at least two possible sources: from the Assyrian asu (to rise) or from the Sanskrit usa (dawn), both with reference to its being the land of the rising sun, i.e., eastern as opposed to Europe, to the west. (From Webster's New Geographical Dictionary, 1988, p82 & Room, Brewer's Dictionary of Names, 1992, p34)AfricaPhylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Egypt: A country in northern Africa, bordering the Mediterranean Sea, between Libya and the Gaza Strip, and the Red Sea north of Sudan, and includes the Asian Sinai Peninsula Its capital is Cairo.United Arab Emirates: A federation of seven states on the southeast portion of the Arabian peninsula: Abu Dhabi, Ajman, Dubai, Fujairah, Ras al-Khaimah, Sharjah and Umm al-Qaiwain. In 1820 a treaty of peace was concluded between Great Britain and native rulers. During the 19th century the rulers agreed to suppression of the slave trade and restriction of foreign relations to Great Britain. The Trucial Council was established in 1952 and defense treaties with Great Britain terminated. In 1971 an independent six-member federation was formed, with Ras al-Khaimah joining the federation in 1972. (From Webster's New Geographical Dictionary, 1988, p1250)Africa, Eastern: The geographical area of Africa comprising BURUNDI; DJIBOUTI; ETHIOPIA; KENYA; RWANDA; SOMALIA; SUDAN; TANZANIA; and UGANDA.History, Ancient: The period of history before 500 of the common era.Middle Cerebral Artery: The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.IraqGeography: The science dealing with the earth and its life, especially the description of land, sea, and air and the distribution of plant and animal life, including humanity and human industries with reference to the mutual relations of these elements. (From Webster, 3d ed)IsraelAsia, Western: The geographical designation for the countries of the MIDDLE EAST and the countries BANGLADESH; BHUTAN; INDIA; NEPAL; PAKISTAN; and SRI LANKA. (From Random House Unabridged Dictionary, 2d ed, 1993 & Webster's New Geographical Dictionary, 1988)Asia, Central: The geographical area of Asia comprising KAZAKHSTAN; KYRGYZSTAN; TAJIKISTAN; TURKMENISTAN; and UZBEKISTAN. The desert region of Kara Kum (Qara Qum) is largely in Turkmenistan and the desert region of Kyzyl Kum (Kizil Kum or Qizil Qum), is in Uzbekistan and Kazakhstan. (From Webster's New Geographical Dictionary, 1988, p233, 590, 636)Livestock: Domesticated farm animals raised for home use or profit but excluding POULTRY. Typically livestock includes CATTLE; SHEEP; HORSES; SWINE; GOATS; and others.Travel: Aspects of health and disease related to travel.Mediterranean Region: The MEDITERRANEAN SEA, the MEDITERRANEAN ISLANDS, and the countries bordering on the sea collectively.EuropeEmigration and Immigration: The process of leaving one's country to establish residence in a foreign country.Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.Simbu virus: A species in the ORTHOBUNYAVIRUS genus of the family BUNYAVIRIDAE family. Previously a large group of serotypes, most are now considered separate species.Agropyron: A plant genus of the family POACEAE. The common name of wheatgrass is also used for other plants in the family.Genetic Variation: Genotypic differences observed among individuals in a population.Ceremonial Behavior: A series of actions, sometimes symbolic actions which may be associated with a behavior pattern, and are often indispensable to its performance.Chromosomes, Human, Y: The human male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans.World Health: The concept pertaining to the health status of inhabitants of the world.Bahrain: An independent state, an archipelago in the western Persian Gulf, northwest of Qatar. It comprises low-lying islands of Bahrain (the largest), Muharraq, Sitra, and several islets. It has extensive oil fields. The name comes from the Arabic al-bahrayn, "the two seas", with reference to its lying in the middle of a bay with its "two seas" east and west of it. (From Webster's New Geographical Dictionary, 1988, p107 & Room, Brewer's Dictionary of Names, 1992, p45)Cyperus: A plant genus of the family CYPERACEAE. SESQUITERPENES are found in some of the species.Asia, Southeastern: The geographical area of Asia comprising BORNEO; BRUNEI; CAMBODIA; INDONESIA; LAOS; MALAYSIA; the MEKONG VALLEY; MYANMAR (formerly Burma), the PHILIPPINES; SINGAPORE; THAILAND; and VIETNAM.Genetics, Population: The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES.Salvadoraceae: A plant family of the order Celastrales, subclass Rosidae, class Magnoliopsida, a small family growing in the tropics. Members contain piperidine alkaloids and GLUCOSINOLATES.History, Medieval: The period of history from the year 500 through 1450 of the common era.Haplotypes: The genetic constitution of individuals with respect to one member of a pair of allelic genes, or sets of genes that are closely linked and tend to be inherited together such as those of the MAJOR HISTOCOMPATIBILITY COMPLEX.Europe, EasternPrevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Arab World: A historical and cultural entity dispersed across a wide geographical area under the administrative, intellectual, social, and cultural domination of the Arab empire. The Arab world, under the impetus of Islam, by the eighth century A.D., extended from Arabia in the Middle East to all of northern Africa, southern Spain, Sardinia, and Sicily. Close contact was maintained with Greek and Jewish culture. While the principal service of the Arabs to medicine was the preservation of Greek culture, the Arabs themselves were the originators of algebra, chemistry, geology, and many of the refinements of civilization. (From A. Castiglioni, A History of Medicine, 2d ed, p260; from F. H. Garrison, An Introduction to the History of Medicine, 4th ed, p126)Communicable Diseases, Emerging: Infectious diseases that are novel in their outbreak ranges (geographic and host) or transmission mode.Phylogeography: A field of study concerned with the principles and processes governing the geographic distributions of genealogical lineages, especially those within and among closely related species. (Avise, J.C., Phylogeography: The History and Formation of Species. Harvard University Press, 2000)Gross Domestic Product: Value of all final goods and services produced in a country in one year.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Islam: A monotheistic religion promulgated by the Prophet Mohammed with Allah as the deity.Emigrants and Immigrants: People who leave their place of residence in one country and settle in a different country.Basic Reproduction Number: The expected number of new cases of an infection caused by an infected individual, in a population consisting of susceptible contacts only.Coronaviridae: Spherical RNA viruses, in the order NIDOVIRALES, infecting a wide range of animals including humans. Transmission is by fecal-oral and respiratory routes. Mechanical transmission is also common. There are two genera: CORONAVIRUS and TOROVIRUS.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Torture: The intentional infliction of physical or mental suffering upon an individual or individuals, including the torture of animals.Dipeptidyl Peptidase 4: A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.Spike Glycoprotein, Coronavirus: A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.Gene Pool: The total genetic information possessed by the reproductive members of a POPULATION of sexually reproducing organisms.DNA, Mitochondrial: Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.International Cooperation: The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.Disease Outbreaks: Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Download our free solidary book to support research on VHL disease