Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.Neisseria gonorrhoeae: A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.Pharyngeal Diseases: Pathological processes involving the PHARYNX.Sexually Transmitted Diseases, Bacterial: Bacterial diseases transmitted or propagated by sexual conduct.Chlamydia Infections: Infections with bacteria of the genus CHLAMYDIA.Sexually Transmitted Diseases: Diseases due to or propagated by sexual contact.Cefixime: A third-generation cephalosporin antibiotic that is stable to hydrolysis by beta-lactamases.Penicillin G Procaine: Semisynthetic antibiotic prepared by combining penicillin G with PROCAINE.Riots: A form of violent crowd behavior which expresses the emotional release of resentments and prejudices, usually relevant to grievances toward the social system.Urethritis: Inflammation involving the URETHRA. Similar to CYSTITIS, clinical symptoms range from vague discomfort to painful urination (DYSURIA), urethral discharge, or both.Syphilis: A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.Firesetting Behavior: A compulsion to set fires.Sex: The totality of characteristics of reproductive structure, functions, PHENOTYPE, and GENOTYPE, differentiating the MALE from the FEMALE organism.Rectal Diseases: Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).Urethra: A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.Ceftriaxone: A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Spectinomycin: An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.Sexual Behavior: Sexual activities of humans.Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.Homosexuality: The sexual attraction or relationship between members of the same SEX.Chlamydia trachomatis: Type species of CHLAMYDIA causing a variety of ocular and urogenital diseases.Trichomonas Infections: Infections in birds and mammals produced by various species of Trichomonas.Prostitution: The practice of indulging in sexual relations for money.Trichomonas Vaginitis: Inflammation of the vagina, marked by a purulent discharge. This disease is caused by the protozoan TRICHOMONAS VAGINALIS.San FranciscoHomosexuality, Male: Sexual attraction or relationship between males.Urethral Diseases: Pathological processes involving the URETHRA.ColoradoLigase Chain Reaction: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.Heterosexuality: The sexual attraction or relationship between members of the opposite SEX.Hospitals, Military: Hospitals which provide care for the military personnel and usually for their dependents.Injections, Intramuscular: Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.Cephalosporins: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.Uterine Cervical Diseases: Pathological processes of the UTERINE CERVIX.Microbial Sensitivity Tests: Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).Cefotaxime: Semisynthetic broad-spectrum cephalosporin.Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.Trichomonas vaginalis: A species of TRICHOMONAS that produces a refractory vaginal discharge in females, as well as bladder and urethral infections in males.Shame: An emotional attitude excited by realization of a shortcoming or impropriety.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.United StatesContact Tracing: Identification of those persons (or animals) who have had such an association with an infected person, animal, or contaminated environment as to have had the opportunity to acquire the infection. Contact tracing is a generally accepted method for the control of sexually transmitted diseases.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Cervix Uteri: The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal.Chlamydia: A genus of the family CHLAMYDIACEAE whose species cause a variety of diseases in vertebrates including humans, mice, and swine. Chlamydia species are gram-negative and produce glycogen. The type species is CHLAMYDIA TRACHOMATIS.WashingtonAnti-Infective Agents: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.Sentinel Surveillance: Monitoring of rate of occurrence of specific conditions to assess the stability or change in health levels of a population. It is also the study of disease rates in a specific cohort such as in a geographic area or population subgroup to estimate trends in a larger population. (From Last, Dictionary of Epidemiology, 2d ed)Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.Condoms: A sheath that is worn over the penis during sexual behavior in order to prevent pregnancy or spread of sexually transmitted disease.BaltimoreNonoxynol: Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.Sexual Partners: Married or single individuals who share sexual relations.Mass Screening: Organized periodic procedures performed on large groups of people for the purpose of detecting disease.Pelvic Inflammatory Disease: A spectrum of inflammation involving the female upper genital tract and the supporting tissues. It is usually caused by an ascending infection of organisms from the endocervix. Infection may be confined to the uterus (ENDOMETRITIS), the FALLOPIAN TUBES; (SALPINGITIS); the ovaries (OOPHORITIS), the supporting ligaments (PARAMETRITIS), or may involve several of the above uterine appendages. Such inflammation can lead to functional impairment and infertility.Vaginal Diseases: Pathological processes of the VAGINA.Ophthalmia Neonatorum: Acute conjunctival inflammation in the newborn, usually caused by maternal gonococcal infection. The causative agent is NEISSERIA GONORRHOEAE. The baby's eyes are contaminated during passage through the birth canal.Contraceptive Devices, Male: Contraceptive devices used by males.Space-Time Clustering: A statistically significant excess of cases of a disease, occurring within a limited space-time continuum.Private Practice: Practice of a health profession by an individual, offering services on a person-to-person basis, as opposed to group or partnership practice.Epidemiologic Factors: Events, characteristics, or other definable entities that have the potential to bring about a change in a health condition or other defined outcome.