Tarmpolypos
Utveckling av tarmpolyper. Såväl neoplastiska (adenom och carcinom) som icke-neoplastiska (hyperplastiska, slemhinnepolyper, inflammatoriska och andra) typer finns.
Tarmpolyper
APC-gener
Adenomatös tjocktarmspolypos
Adenomatös tjocktarmspolyposprotein
Adenomatous polyposis coli (APC) protein is a tumor suppressor protein that plays a crucial role in regulating cell growth and division in the colon. In a single sentence, Adenomatous Polyposis Coli (APC) protein can be defined as a vital protein product of the APC gene, whose normal function involves preventing excessive cell proliferation and promoting programmed cell death, but mutations in this gene can lead to the development of numerous adenomatous polyps in the colon, significantly increasing the risk of colorectal cancer.