A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.

'Ethylamines' are organic compounds containing an ethyl group (two carbon atoms) bonded to an amino group (-NH2), which can vary in their complexity and properties, playing a role in various biological processes or utilized in the synthesis of numerous pharmaceuticals and chemicals.

A phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. (From Smith and Reynard, Textbook of Pharmacology,1991, p431)

A halogen with the atomic symbol Br, atomic number 36, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.

Death of cells in the KIDNEY CORTEX, a common final result of various renal injuries including HYPOXIA; ISCHEMIA; and drug toxicity.

Derivatives of orthoaminobenzoic acid that have a phenyl group bound to the orthoamino nitrogen. Members modulate ION CHANNELS and are used as ANTI-INFLAMMATORY AGENTS.

Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

The internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces.

The withholding of water in a structured experimental situation.